54 patents in this list

Updated:

Traditional sugar alternatives like sugar alcohols and artificial sweeteners can cause significant gastrointestinal distress, with up to 70% of consumers reporting adverse effects including bloating, gas, and osmotic diarrhea when consuming more than 20-30g per day. Meanwhile, natural high-intensity sweeteners often present bitter aftertastes that limit their practical application in food products.

The core challenge lies in developing sweetener systems that deliver sugar-like taste and functionality while maintaining gut microbiome health and avoiding digestive side effects.

This page brings together solutions from recent research—including oligosaccharide compositions with specific polymerization degrees, colloid-stabilized sugar alcohol formulations, and hybrid systems combining resistant fiber with natural sweeteners. These and other approaches focus on creating practical alternatives that food manufacturers can implement while maintaining product quality and consumer acceptance.

1. Sweetener Composition with Allulose, Erythritol, Soluble Corn Fiber, and Salt

Andrew Barninger, Lucas Scheider, 2024

A nonnutritive sweetener composition having improved physical properties for use in food and beverages. The sweetener composition contains a blend of allulose, erythritol, soluble corn fiber, and salt. The specific ratios of the ingredients are optimized to provide a sweetener that closely matches the taste, texture, and functionality of sucrose (table sugar) without the negative metabolic impacts of sucrose. The sweetener can replace sucrose in recipes without needing to make other ingredient substitutions.

2. Sweetener Composition with Erythritol, Allulose, Enzyme-Treated Stevia, and Monk Fruit Extract in Specified Proportions and Particle Size

INTAKE CO LTD, 2023

Low-calorie sweetener composition that can replace sugar 1:1 and provides similar sweetness and taste to sugar. The composition contains erythritol, allulose, enzyme-treated stevia, and Monk fruit extract. The amounts are 30-50% allulose, 0.3-3.0% enzyme-treated stevia, and 0.01-0.03% Monk fruit extract based on erythritol weight. The average particle size is 150-250 µm. This composition provides a sweet taste similar to sugar without the disadvantages of sugar alcohols like diarrhea and bitter aftertaste.

3. Sweetener Composition with Thunbergia Vine Extracts and Camellia Sinensis Caffeoylquinic Acids

GIVAUDAN S A, GIVAUDAN SA, 2023

Using extracts or fractions from the Thunbergia vine and caffeoylquinic acids from Camellia sinensis to improve sweetness, mouthfeel, and mask off-flavors in low-calorie sweeteners. These extracts and acids enhance sweetness perception, roundness, and fullness of sweeteners like Reb A, sucralose, and stevia. They also reduce licorice-like aftertaste and persistent sweetness. Adding them to sweetened products improves the taste profile and sensory experience compared to using the sweeteners alone.

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4. Sweetener Liquid Composition with Food Colloids and Sugar Alcohols for Modulating Gastrointestinal Absorption

ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD., 2023

A sweetener liquid for preventing and relieving intestinal sugar alcohol intolerance that contains specific types and amounts of food colloids like low-esterification pectin, κ-carrageenan, and locust bean gum, along with xylitol, maltitol, and sorbitol. The formulation in combination with the colloids helps slow the absorption of sugar alcohols in the gastrointestinal tract, balancing osmotic pressures and preventing diarrhea caused by excessive sugar alcohol ingestion.

5. Sweetener Syrup Composition with High Soluble Indigestible Maltodextrin and Reduced Mono and Disaccharides Content

Archer Daniels Midland Company, 2023

Reduced-sugar sweetener syrups that contain a high percentage of soluble indigestible maltodextrin and a low percentage of mono and disaccharides. The syrups are used to make low-sugar, high fiber food products like snack bars, pudding, and ketchup.

6. Sweetener Composition of Glucose and Purified Hemicellulose from Lignocellulosic Biomass

Comet Biorefining Inc., 2023

Sweetener composition comprising glucose and purified hemicellulose from lignocellulosic biomass. The hemicellulose components include xylose, xylo-oligosaccharides, and xylan. The glucose is derived from cellulose and the hemicellulose is obtained from plant sources. The composition provides a lower calorie and lower glycemic index sweetener option that can be used in foods, beverages, pharmaceuticals, and supplements.

7. Steviol Glycoside Compositions Incorporating Minor Glycosides for Sugar Taste Mimicry

PURECIRCLE USA INC., 2023

Natural sugar substitute compositions that mimic the taste of sugar, using steviol glycosides derived from the Stevia rebaudiana plant. The compositions contain lower levels of the major approved steviol glycosides but also include minor steviol glycosides. These less purified compositions surprisingly provide sweetness and flavor similar to higher purity extracts, allowing more efficient and cost-effective production of natural sweeteners.

8. Sweetener and Flavor Enhancer Composition with Plant-Derived Compounds

アナリティコン ディスカバリー ゲーエムベーハー, ブレイン アーゲー, ANALYZE CON DISCOVERY GAME M BEHER, 2023

Sweeteners and flavor enhancers for use in foods and beverages that provide a sweet taste and enhance the sweetness of other sweeteners. The sweeteners are compounds found in plants like Momordica grosvenori (Kewra) and extracts from plants like Stevia, Momordica, and Siraitia. They can be used as standalone sweeteners or added to other sweeteners to enhance their sweetness. The compounds include neohesperidin dihydrochalcone, naringin dihydrochalcone, stevioside, steviobioside, rebaudioside A-M, dulcoside, and rhodoside.

9. Compositions of Oligosaccharide Mixtures with Defined Polymerization Degrees and Ratios

CAMBRIDGE GLYCOSCIENCE LTD, 2023

Food, cosmetic and nutraceutical compositions containing mixtures of oligosaccharides with specific degrees of polymerization for use as sugar substitutes. The compositions can provide bulk, sweetness, and other functional properties of sugar while being lower in calories. The compositions comprise specific ratios of cell- and xylo-oligosaccharides with varying chain lengths. The oligosaccharide mixtures can be produced from cellulose using enzymes.

10. Powdered Sweetener Composition with High-Intensity Sweetener, Non-Sucrose Bulk Sweetener, and Low-Digestible Carbohydrate Polymer

BAYN SOLUTIONS AB, 2023

A low-calorie sweetener composition that mimics the taste and mouthfeel of sucrose but has fewer calories, a lower glycemic index and is easier to handle in food manufacturing. The composition is a powder made of particles containing a high-intensity sweetener, a non-sucrose bulk sweetener, and a low-digestible carbohydrate polymer like dextrin. The high-intensity sweetener provides the sweetness, the bulk sweetener provides the body, and the low-digestible carbohydrate provides the mouthfeel. The particles are formed by mixing the sweeteners with water and then mixing that with the polymer powder and drying the mixture.

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11. Sweetener Composition with Specific Ratios of Stevia Extract, Citric Acid, Erythritol, and Trifoliate Glycerin

HUNAN NUTRAMAX INC, 2023

A composition containing stevia extract, citric acid, erythritol, and trifoliate glycerin in specific ratios for use as a sweetener in food applications. The composition provides a sweet taste without calories and improves taste compared to pure stevia extract. The ratios of the ingredients are: 20 parts stevia extract, 2-3 parts citric acid, 31-35 parts erythritol, and 30-40 parts trifoliate glycerin.

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12. Sweetener Compositions Combining Cellulose-Derived Glucose and Purified Hemicellulose from Lignocellulosic Biomass

Comet Biorefining Inc., 2022

Sweetener compositions for foods and beverages with reduced calories and glycemic index compared to regular sugars. The compositions are made by combining glucose derived from cellulose with purified hemicellulose derived from lignocellulosic biomass. The sweeteners have similar sweetness to sugar but contain soluble fiber components and are derived from plant biomass.

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13. Natural Sweetener Composition with Steviol Glycosides, Mogrosides, and Glycine Components

Franco Cavaleri, 2022

Reduced carbohydrate natural sweeteners made from extracts of stevia, monk fruit and gymnema sylvestre. The sweeteners contain specific components including steviol glycosides from stevia, mogrosides from monk fruit, glycine, and optionally gymnemic acid from gymnema sylvestre. The sweeteners are designed to provide a low carbohydrate, natural alternative to sugar that doesn't cause gastrointestinal distress.

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14. Natural Sweetener Composition with D-Allulose, Cane Sugar, and Monk Fruit Extract

Loren Miles, 2022

A 50% reduction in calorie natural sweetener composition for baking and food/beverage products that tastes like sugar but has significantly fewer calories. The composition contains a blend of three ingredients: D-allulose, cane sugar, and monk fruit extract. The exact ratios can vary within certain ranges, but a preferred composition has 55.5% D-allulose, 44.4% cane sugar, and 0.1% monk fruit extract. This provides a natural sweetener that mimics the taste, texture, and functionality of sugar in baking, while cutting the calories in half.

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15. Oligosaccharide Compositions with Mixed Polymerization Degrees from Enzymatic Polysaccharide Processing

Cambridge Glycoscience Ltd, 2022

Oligosaccharide compositions that are sugar substitutes in food, cosmetics, and nutraceuticals. The compositions contain mixtures of oligosaccharides with varying degrees of polymerization, like cello-oligosaccharides, xylo-oligosaccharides, mixed-linkage glucan oligosaccharides, and manno-oligosaccharides. The compositions have improved properties like taste, texture, solubility, and mouthfeel compared to single oligosaccharides. They can be produced using enzymatic reactions on inexpensive polysaccharide starting materials.

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16. Sugar Substitute Composition with Digestion Resistant Soluble Fiber, Luo Han Guo Extract, and Flavor Masking Agent

SweetScience LLC, 2022

A natural sugar substitute that contains digestion resistant soluble fiber, Luo Han Guo extract, and a flavor masking agent. The fiber is derived from various sources and provides low-calorie sweetness with prebiotic effects. It tastes like sugar without the bitter aftertaste of other natural sweeteners.

17. Syrup Composition with Enzymatically Hydrolyzed and Deglucosated Lactose Containing Tagatose, Galactose, and Glucose

INALCO S.R.L., 2021

A syrup containing tagatose, galactose, and glucose as a low-cost sweetener and prebiotic. The syrup is made by enzymatically hydrolyzing lactose to glucose and galactose, then deglucosating it to remove most of the glucose. The resulting solution is further processed to concentrate and purify the tagatose and galactose.

18. Sugar Substitute Composition with Digestion-Resistant Soluble Fibers and Natural Extracts

SWEETSCIENCE LLC, 2021

Sugar substitute derived from natural ingredients like digestion-resistant soluble fibers that provides similar properties and characteristics as sugar without the calories and glycemic index. The sugar substitute compositions include ingredients like digestion-resistant soluble fibers derived from tapioca, natural fruit extracts like Luo Han Guo, and flavor masking agents. These compositions can be used as sugar alternatives in food and beverages.

19. Granular Composition with Predominant Xylitol Content and Extrusion Granulation Process

AMOREPACIFIC CORPORATION, 2021

A granular composition with high sugar alcohol content that can be used to make functional foods with good taste and texture. The composition contains sugar alcohols like xylitol and erythritol, with xylitol content higher than erythritol. It may also contain dietary fiber, lactic acid bacteria, citric acid, lactose, and fragrance. Granules with improved preference can be prepared using an extrusion granulation process.

20. Sweet Composition with Low Glycemic Index Sugars Excluding Fructose and Artificial Sweeteners

Seattle Gummy Company, 2021

A low glycemic index sweet composition for food and drinks that is safe for diabetics and provides a natural sweet taste without artificial sweeteners. The composition is made of low GI sugars like psicose, sorbose, tagatose, isomaltulose, and trehalose, which have minimal impact on blood sugar levels. It is free of fructose and sugar substitutes. The composition can also contain fibers, proteins, vitamins, minerals, antioxidants, and flavorings.

21. Non-Digestible Oligosaccharides with Monosaccharide Unit Incorporation

22. Oligosaccharide Composition from Cellobiose, Xylo-Oligosaccharides, Mixed-Linkage Glucan Oligosaccharides, and Manno-Oligosaccharides

23. Composition with Enhanced Gastrointestinal Tolerance for Low-Digestible Sweetener Products

24. Enzymatic Conversion of Carbohydrates in Liquid Nutrient to Altered Carbohydrates

25. Sweetener Composition Comprising Isomaltulose, Beet Sugar, and Monk Fruit Extract

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