10 patents in this list

Updated:

This page provides an overview of the latest advancements in prosthetic heart valves that incorporate annular support technology.

Prosthetic heart valves play a vital role in treating heart conditions by replacing damaged or diseased heart valves. The annular support technology used in these valves provides increased stability and durability, ensuring proper functionality and longevity. The annular support helps maintain the correct positioning of the prosthetic valve within the patient's heart, minimizing the risk of displacement or leakage. This technology also improves the overall hemodynamic performance of the valve, promoting optimal blood flow and reducing the strain on the heart.

The development of prosthetic heart valves with annular support involves various technological challenges. Designing a support structure that is biocompatible, strong, and flexible enough to withstand the dynamic nature of the heart is crucial. The annular support must be able to provide sufficient anchorage and stability without impeding the natural movement of the heart. Furthermore, ensuring that the prosthetic valve fits securely within the annular support, while allowing for effective opening and closing, requires precise engineering and careful consideration of materials and manufacturing processes.

1. Hybrid Prosthetic Heart Valve with Expandable Stent for Easy Replacement

Edwards Lifesciences Corporation, 2023

A prosthetic heart valve configured to receive a prosthetic heart valve, such as a catheter-delivered (transcatheter) prosthetic heart valve, therein. The hybrid valve has an expandable stent structure at the inflow end to allow post-implant expansion to receive a second valve without explanting the first. The expandable stent is sized to fit normally in the annulus but can be dilated to receive a replacement valve. The expandable stent can have a flared frame or compressible struts that expand when subjected to dilation forces.

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2. Percutaneously Implantable Annular Support for Aortic Valve Repair

EDWARDS LIFESCIENCES CORPORATION, 2023

A medical device for repairing aortic insufficiency by reducing the diameter of the aortic valve annulus. It involves a percutaneously implantable annular support structure that can be expanded and positioned below the aortic valve to engage the leaflets and reduce the effective annulus diameter. This improves valve closure to prevent regurgitation. The support structure may also be overexpanded to radially constrict the annulus for long term reduction.

3. Two-Stage Prosthetic Heart Valve for Simplified Implantation and Reduced Bypass Time

Edwards Lifesciences Corporation, 2023

Prosthetic heart valve that can be implanted more quickly and easily than current valves, reducing the time needed on cardiopulmonary bypass. The valve has a two-stage design where a radially expandable base stent anchors to the heart valve annulus first, then a valve component with an expandable coupling stent connects to the base stent.

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4. Two-Stage Prosthetic Heart Valve for Quick Implantation

Edwards Lifesciences Corporation, 2022

Prosthetic heart valve designed to be implanted in less time than current devices. It uses a two stage design where a tissue anchoring member is first deployed to secure to the native valve annulus, followed by attachment of the valve member to the anchoring member. This allows for faster implantation compared to sewing in a valve. The anchoring member can be expandable to quickly anchor in place. The valve member can then be attached to the anchoring member.

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5. Minimally Invasive Mitral Valve Therapy Device with Secure Anchoring System

Caisson Interventional LLC, 2022

A mitral valve therapy device that can be deployed through minimally invasive procedure and secured to the native valve annulus. The device has an expandable frame and multiple anchors extending from the frame. Each anchor has a foot angled relative to the frame axis to contact the sub-annular collagenous tissue for secure anchoring. The foot has a shape and area that minimizes pressure on surrounding heart tissue to avoid puncture.

6. Transcatheter Prosthetic Heart Valve with Orthogonal Compression and Anchoring Tabs

VDyne, Inc., 2022

A transcatheter prosthetic heart valve that can be side delivered through a small catheter and then expand once deployed in the heart. The valve has a compressible frame with anchoring tabs and a central flow component. The frame is compressed orthogonal to the catheter axis. After release, it expands to engage the native valve annulus. The tabs anchor the valve while the central portion allows unidirectional blood flow.

7. Eversion-Based Percutaneous Transcatheter Prosthetic Valve Replacement with Tethered Securement

CorMatrix Cardiovascular, Inc., 2021

Percutaneous transcatheter valve replacement for dysfunctional heart valves like the mitral, tricuspid, and aortic valves. The method involves using a specially designed prosthetic valve that can be everted to a compressed pre-deployment configuration to fit inside a catheter, then expanded to a deployed configuration once positioned at the valve annulus. The expanded valve is secured in place with tethers that pierce the surrounding tissue. This allows precise positioning and secure attachment without sutures or adhesives.

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8. Innovative Collapsible Prosthetic Heart Valve with Enhanced Positioning and Reduced Regurgitation

St. Jude Medical, Cardiology Division, Inc., 2021

A collapsible prosthetic heart valve designed for implanting in aortic valve replacement procedures that has improved performance and reduced regurgitation compared to conventional valves. The valve has a stent with a unique cuff shape and extended landing zone that helps position the valve supra-annularly in the native aortic valve. This allows the prosthetic leaflets to fully open above the compressed native leaflets, reducing regurgitation and improving blood flow. The cuff also positions the valve stent deeper in the aortic annulus to anchor it.

9. Modular Mitral Valve Replacement System with Customizable Anatomy Fit

CARDIOVALVE LTD., 2021

A mitral valve replacement system that allows customization of the valve anatomy to fit the patient. The system has a modular design with a separate expandable support ring that can be anchored at the native valve annulus using guide wires. A collapsible prosthetic valve can then be deployed and attached to the ring at a chosen location. The ring and valve parts can be selected with appropriate sizes and shapes to match the patient's native anatomy.

10. Percutaneous Prosthetic Heart Valves with Enhanced Annular Sealing

Edwards Lifesciences Corporation, 2020

Catheter-based prosthetic heart valves that can be implanted percutaneously to replace damaged natural heart valves. The valves have structures to seal against the irregular shape of the native valve annulus for better performance. The sealing members are configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. This helps prevent blood leaking between the valve and tissue.

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