15 patents in this list

Updated:

This page presents various solutions and advancements in the field of prosthetic heart valves, specifically focusing on the transvascular delivery method.

The transvascular delivery method is a minimally invasive technique for implanting prosthetic heart valves. It involves inserting the valve through the blood vessels rather than open-heart surgery. This method has revolutionized the treatment of heart valve diseases as it reduces risks, hospital stays, recovery time, and overall patient discomfort. The transvascular delivery method has enabled many patients who were not suitable candidates for traditional open-heart surgery to receive life-saving valve replacements.

The transvascular delivery method presents unique technological challenges. The prosthetic heart valves need to be designed to be compact and flexible, allowing them to be inserted through narrow blood vessels. They should be able to navigate complex anatomical structures while maintaining their functionality and structural integrity. Precision and accuracy are crucial during the deployment process to ensure proper placement and functionality of the valve. Additionally, the transvascular delivery method requires specialized imaging technologies and catheter-based delivery systems, which call for continuous advancements in medical device technology.

1. Percutaneous Delivery System for Prosthetic Heart Valves with Inverting Sleeve Mechanism

Edwards Lifesciences Corporation, 2023

A prosthetic heart valve that can be delivered through less invasive percutaneous techniques by compressing or folding the valve during delivery then transitioning it to an expanded operating configuration once in place. The valve has a stent, leaflets, and a flexible sleeve connecting them. The valve can transform from a delivery configuration with the leaflets outside the stent to an operating configuration with the leaflets inside the stent by pushing the leaflets into the stent as the sleeve inverts. This allows a smaller delivery profile. The valve can be anchored by outward force on the native valve annulus when expanded.

2. Transcatheter Delivery System for Prosthetic Heart Valves with Enhanced Anchoring Stability

VDyne, Inc., 2023

Prosthetic heart valve that can be compressed and expanded for transcatheter delivery. The valve has distal, proximal, and septal subannular anchoring elements to secure it in a native valve annulus. The septal element extends below the annulus to stabilize the valve against rotation. This anchoring configuration allows the valve to be side-loaded into a catheter for delivery, instead of fully compressing it radially. It is released from the catheter to expand and anchor in the annulus. The septal element pinning the native leaflet prevents dislodgement.

US20230157816A1-patent-drawing

3. Supra-Annular Deployment Method for Prosthetic Heart Valves

MEDTRONIC, INC., 2023

A method for loading and deploying prosthetic heart valves in a way that allows for delivery even if the ventricle volume is insufficient to accommodate the valve during unsheathing. The method involves using a specialized delivery device that compresses the valve in a way that allows it to be unsheathed supra-annularly. This means the valve can be unsheathed from the top side of the annulus rather than going through it. This avoids the need for ventricle access during unsheathing.

4. Catheter System with Retractable Mechanism for Transvascular Prosthetic Heart Valve Implantation

JenaValve Technology, Inc., 2023

Catheter system for transvascular implantation of prosthetic heart valves with self-expanding anchoring systems that can be implanted with minimal invasion and reduced risk to the patient. The catheter has a flexible, bendable distal section to navigate through the aorta without damaging the vessel walls. It also has a mechanism to retract the valve into the catheter if it is improperly positioned for repositioning rather than attempting to remove it.

US20230100094A1-patent-drawing

5. Minimally Invasive Percutaneous Delivery System for Prosthetic Heart Valves

Medtronic, Inc., 2023

Percutaneously implantable prosthetic heart valves that can be deployed through minimally invasive procedures. The valves use collapsible stents with docking structures that allow percutaneous delivery and expansion in the heart. The stents have flexible wires and posts that can be compressed for delivery on catheters, then expanded and rotated into position. Valves are attached to the stents with features to distribute stress for durability. The delivery systems allow retrieval and repositioning of partially deployed valves.

US11607311B2-patent-drawing

6. Side-Delivery Transcatheter Prosthetic Heart Valve with Anchoring Tabs for Minimally Invasive Deployment

VDyne, Inc., 2022

A transcatheter prosthetic heart valve that can be side delivered through a small catheter and then expand once deployed in the heart. The valve has a compressible frame with anchoring tabs and a central flow component. The frame is compressed orthogonal to the catheter axis. After release, it expands to engage the native valve annulus. The tabs anchor the valve while the central portion allows unidirectional blood flow.

7. Two-Part Expandable Prosthetic Mitral Valve for Transcatheter Delivery

Caisson Interventional, LLC, 2022

Transcatheter delivery of a two-part prosthetic mitral valve for implantation within the native mitral valve. The valve has an anchor assembly and a nested valve assembly that expand separately. The anchor engages the native annulus while the valve seals with the leaflets. The two-part design enables smaller delivery size through catheters. The valve parts are deployed in stages, first expanding the anchor then the valve inside it.

US20220096231A1-patent-drawing

8. Percutaneous Transcatheter Deployment System for Prosthetic Mitral Valves

Caisson Interventional, LLC, 2022

A percutaneous, transcatheter deployment system for mitral valves. The system has multiple catheters that can engage each other and releasably couple to the prosthetic mitral valve components. A deployment frame with clamps allows simultaneous movement of the catheters to position and release the valve components.

US20220079757A1-patent-drawing

9. Invertible Frame Design for Transvascular Prosthetic Heart Valve Delivery

Tendyne Holdings, Inc., 2022

Prosthetic heart valve that can be moved to an inverted configuration for delivery of the prosthetic valve to within a patient's heart. The prosthetic valve includes an outer frame that can be inverted relative to an inner frame when the prosthetic valve is in a biased expanded configuration. This allows the valve to be collapsed for delivery in a sheath, then expanded in the heart.

US20220000617A1-patent-drawing

10. Anchoring Tether Coupling for Transcatheter Prosthetic Heart Valve Delivery and Placement

Tendyne Holdings, Inc., 2021

Prosthetic heart valve that can be used for transcatheter delivery and placement to replace damaged mitral valves. The prosthetic valve has features to aid delivery and positioning. It includes an anchoring tether coupling portion to secure a tether that attaches the valve to the heart wall. The tether maintains valve position. The coupling portion can also engage with a positioning device to help position the valve during delivery.

US11191639B2-patent-drawing

11. Catheter-Based System for Retrieval and Repositioning of Transcatheter Prosthetic Heart Valves

Tendyne Holdings, Inc., 2021

A catheter-based system for retrieving and repositioning transcatheter prosthetic mitral valves from inside the heart. The system involves using a specialized catheter assembly to capture, collapse, and remove a previously implanted mitral valve through a transseptal approach. This enables percutaneous retrieval and repositioning of the mitral valve without open heart surgery. The catheter assembly has multiple catheters and a snare to invert and collapse the valve for retrieval through the catheter lumen.

US20210267757A1-patent-drawing

12. Innovative Percutaneous Prosthetic Mitral Valve with Independent Anchor Deployment

Caisson Interventional, LLC, 2021

Percutaneously implantable prosthetic mitral valve designed for secure fixation in the native mitral valve anatomy, ease of deployment and ability to be repositioned. The valve has separate anchor and valve components that can be deployed independently. The anchor expands to engage sub-annular tissue and stabilize the valve, while the valve attaches to the anchor and replaces the native valve function. The valve and anchor can be separately mounted to a delivery catheter system.

13. Transcatheter Heart Valve Deployment System with Crimping Tool

Epygon, 2020

Transcatheter delivery system for heart valve prosthesis implantation with a crimping tool to compress the valve for loading into a delivery catheter. The system allows transcatheter deployment of self-expanding heart valve prostheses via minimally invasive techniques. The crimping tool reduces the valve diameter so it can be loaded into the catheter. Once deployed at the implant site, the valve self-expands to its functional size.

14. Re-Collapsible Prosthetic Heart Valve Delivery System with Reinforced Catheter

Symetis SA, 2019

Delivery system for transfemoral delivery of collapsible prosthetic heart valves that can be re-collapsed if necessary. The delivery system has a flexible catheter with a reinforced tubular member made of helically wound metal strands. The strands are joined together and/or coated with polymer to prevent sliding and maintain dimensional stability under load. This allows safe transmission of high forces to re-collapse the valve if needed. The re-expandable valve can be partially collapsed if repositioning or removal is required.

15. Real-Time 3D Mapping and Imaging Enhancement for Transcatheter Heart Valve Procedures

Edwards Lifesciences Corporation, 2019

Enhanced cardiac imaging and navigation for transcatheter heart valve procedures. The technique involves using a small electrophysiological 3D mapping catheter to create a detailed 3D map of the heart. This map is displayed in real-time during the procedure along with other imaging modalities like echocardiography or fluoroscopy. The combined imaging provides enhanced visualization for accurate positioning and deployment of transcatheter heart valves.

Request the PDF report with complete details of all 15 patents for offline reading.