Probiotics for Weight Control
105 patents in this list
Updated:
Recent clinical studies have demonstrated that gut microbiota play a critical role in weight regulation, with specific bacterial strains showing measurable effects on lipid metabolism, glucose homeostasis, and appetite signaling. When introduced in controlled doses of 10⁸-10¹⁰ CFU per day, certain probiotic strains have been shown to reduce body fat percentage by 3-5% over 12-week intervention periods.
The fundamental challenge lies in identifying and maintaining viable probiotic strains that can effectively modulate metabolic pathways while surviving the harsh conditions of the gastrointestinal tract.
This page brings together solutions from recent research—including stress-adapted probiotic strains with enhanced lipid metabolism capabilities, novel Lactobacillus and Bifidobacterium species with demonstrated weight management effects, and engineered bacterial combinations that show synergistic metabolic benefits. These and other approaches focus on practical supplementation strategies that can be integrated into clinical weight management protocols.
1. Composition Containing Lactobacillus Gasseri MHS-Lga-12 and Prebiotics
Zhejiang Miaohuoshi Biotechnology Co., Ltd., 2024
Composition for reducing body fat content and body weight by regulating intestinal flora using a specific strain of lactobacillus gasseri (MHS-Lga-12) in combination with prebiotics. The composition contains the MHS-Lga-12 strain along with prebiotics like xylitol and skim milk powder. It aims to improve intestinal health and reduce body fat levels by modulating the gut microbiome.
2. Probiotic Composition with Non-Histamine Producing Bacterial Strains from Lactobacillus, Enterococcus, and Bifidobacterium Genera
INST ALLERGOSAN PHARMAZEUTISCHE PRODUKTE FORSCHUNGS U, INSTITUT ALLERGOSAN PHARMAZEUTISCHE PRODUKTE FORSCHUNGS- U, WINCLOVE HOLDING B V, 2024
A probiotic composition for treating weight loss conditions like cachexia and wasting syndromes. The composition contains a combination of multiple different bacteria species from genera like Lactobacillus, Enterococcus, and Bifidobacterium. Administering this probiotic mixture allows increased accumulation of white adipose tissue in subjects with weight loss conditions. The specific bacterial strains selected aim to avoid histamine production to mitigate potential negative effects.
3. Probiotic and Prebiotic Composition with Specific Carbohydrate and Bacterial Strain Ratios
Shandong New Era Pharmaceutical Co., Ltd., SHANDONG NEW TIME PHARMACEUTICAL CO LTD, 2024
A composition of probiotics and prebiotics that can enhance weight loss when used in conjunction with the weight loss drug orlistat. The composition contains specific amounts of resistant dextrin, inulin, corn starch, maltodextrin, and stachyose along with lactic acid bacteria strains like Lactobacillus plantarum, Lactobacillus acidophilus, Bifidobacterium bifidum, and Lactobacillus paracasei.
4. Composition of Fiber and Probiotics with Variable Resilience-Enhancing Properties for Microbiome Stability
SOC DES PRODUITS NESTLE S A, Nestlé Products Company SA, 2023
Enhancing microbiome resilience to improve gut health by administering a combination of fiber and probiotics, especially during times of microbiome stress like a high-fat diet. The fiber and probiotic mixture improves microbiome resilience, intestinal transit, and gut barrier function after a stress like a high-fat, low-fiber diet. Administering this fiber-probiotic blend to subjects undergoing microbiome stressors can prevent or mitigate negative impacts on gut health.
5. Lactic Acid Bacteria Composition with Lactobacillus plantarum PL-02, Lactobacillus acidophilus TYCA06, and Lactobacillus casei CS-773
GLAC BIOTECH CO., LTD, 2023
Composition of lactic acid bacteria strains that can reduce body fat, enhance muscle performance and endurance, and reduce fatigue. The strains are Lactobacillus plantarum PL-02, Lactobacillus acidophilus TYCA06, and Lactobacillus casei CS-773. Administering these strains can decrease body weight, promote exercise performance, and enhance body composition.
6. Probiotic Composition Containing Pediococcus pentosaceus LN-PT16 with Auxiliary Agents
GUANGDONG YIKEWEI BIOTECHNOLOGY CO LTD, 2023
Probiotic composition with fat-reducing and hypoglycemic properties for preventing and treating obesity and blood sugar issues. The composition contains strains like Pediococcus pentosaceus LN-PT16 along with other probiotics and auxiliary agents. It aims to reduce fat, lower cholesterol, decrease insulin, lower blood sugar, improve glucose tolerance, and reduce weight. The composition can be used in functional foods, supplements, and medications.
7. Lactobacillus rhamnosus Strain CHCC15871 for High Diacetyl Production in Dairy Fermentation
Chr. Hansen A/S, 2023
Composition for producing dairy products with enhanced creamy flavor using a Lactobacillus rhamnosus strain that produces high levels of diacetyl without affecting rheology. The composition can be added to milk to make yogurt, cheese, etc. The strain is obtained from a deposit called CHCC15871. The strain can be used alone or in combination with other lactic acid bacteria to ferment the milk. The resulting products have increased diacetyl for a creamy flavor.
8. Method for Modulating Lipid Absorption via Lactobacillus Content Regulation in Mammalian Digestive Tract
SHANGHAI INST OF NUTRITION AND HEALTH CHINESE ACADEMY OF SCIENCES, SHANGHAI INSTITUTE OF NUTRITION AND HEALTH CHINESE ACADEMY OF SCIENCES, 2023
Modifying lipid absorption or body weight in normal body weight or obese mammals. The modulation includes reducing the content of lactobacillus in the digestive tract, thereby increasing lipid absorption or body weight; or regulating the content of lactobacillus in the digestive tract (including stomach or intestinal tract).
9. Dietary Composition Containing Chitosan, Bifidobacterium Longum, Lactobacillus Rhamnosus, Sodium Alginate, and Fruit-Vegetable Compound
HANGZHOU ZHILING BIOLOGICAL TECH CO LTD, HANGZHOU ZHILING BIOLOGICAL TECHNOLOGY CO LTD, 2023
Dietary composition that can reduce blood fat and lose weight. The composition comprises chitosan, bifidobacterium longum metaplasia, lactobacillus rhamnosus metazoan, sodium alginate and fruit and vegetable compound.
10. Probiotic Composition of Lacticaseibacillus paracasei S38 and Bacillus coagulans BC198
Syngen Biotech Co., Ltd, 2023
A combination of two strains of probiotics, Lacticaseibacillus paracasei S38 and Bacillus coagulans BC198, that has been demonstrated to effectively improve body composition and aid in weight loss. The combination of these specific strains shows additive effects compared to administration of each strain alone.
11. Probiotic Composition of Lacticaseibacillus paracasei S38 and Bacillus coagulans BC198 with Synergistic Strain Interaction
Syngen Biotech Co., Ltd, 2023
A combination of two probiotic strains, Lacticaseibacillus paracasei S38 and Bacillus coagulans BC198, that effectively improve body compositions by aiding weight loss and reducing body fat. The strains, isolated from human feces and green malt, respectively, have synergistic effects when administered together at lower doses compared to individually. This combination helps inhibit lipogenesis, reduce appetite, increase butyric acid production, and promote beneficial gut bacteria like Akkermansia muciniphila and Ruminococcaceae. It can be used as a probiotic supplement, food, or medication to aid weight loss and body composition improvement.
12. Probiotic Composition with Lab4P Strains and Fiber-Prebiotic Matrix
ALAND NUTRIMENT TAIZHOU CO LTD, 2023
Probiotic composition and preparation methods for synergistic weight management. The composition contains two specific strains of probiotics, Lab4P, along with dietary fiber, prebiotics, and sweeteners. The probiotics are Lactobacillus acidophilus CUL21, Bifidobacterium animalis subsp. lactis CUL34, Bifidobacterium bifidum CUL20, and Lactobacillus plantarum CUL66. The composition can be formulated into powders, tablets, capsules, and beverages for weight management applications. The strains are combined with fiber, prebiotics, and sweeteners to provide multiple weight management benefits like appetite suppression, cholesterol reduction, and improved gut health.
13. Probiotic Composition with Specific Lactobacillus and Bifidobacterium Strains and Nutrient Excipients
Jiangsu Xin Shen'ao Biotechnology Co., Ltd., JIANGSU NEW-BIO TECH CO LTD, 2023
Probiotic composition to alleviate adverse reactions caused by excessive exercise. The composition contains a specific blend of lactobacillus and bifidobacterium strains, along with excipients like whey protein, resistant dextrin, fructooligosaccharides, erythritol, lactitol, and glucosyl stevia. The probiotic strains are lactobacillus plantarum, lactobacillus rhamnosus, lactobacillus acidophilus, lactobacillus fermentum, lactobacillus reuteri, bifidobacterium lactis, and bifidobacillus breve. The composition aims to mitigate weight loss and other adverse effects from intense exercise by promoting intestinal health.
14. Probiotic Bacteria with Stress-Induced Metabolic Pathways for Lipid Metabolism
University of Pittsburgh—of the Commonwealth System of Higher Education, 2023
Modifying the metabolism of probiotic bacteria to reduce lipid absorption and thus regulate body weight. The probiotics are subjected to stress-based directed evolution to develop strains that actively metabolize lipids before being absorbed by the host. The modified probiotics are then administered to overweight or obese subjects to decrease lipid absorption and help manage their weight.
15. Probiotic Composition with Lactobacillus Strains for Modulating Gut Permeability and Ethanolamine Metabolism
University of South Florida, 2023
Using human-derived probiotics like Lactobacillus to treat increased gut permeability and metabolic disorders like obesity and diabetes. The disclosure provides methods to reduce intestinal leakiness and inflammation by administering probiotics like Lactobacillus to patients. It also describes increasing ethanolamine metabolism in obese/diabetic patients using probiotics like Lactobacillus rhamnosus strain HL-200. The probiotics can be combined with antidiabetic drugs or weight management drugs.
16. Fruit and Vegetable Fermentation Formula with Dietary Fiber and Plant Extract Integration
GUANGDONG GNPP BIOSCIENCES INC, 2023
Fruit and vegetable fermentation and dietary fiber and plant extract combined formula that has the effects of rich nutrition, appetite suppression, satiety enhancement, bowel relaxing and carbohydrate and fat absorption blocking. The formula includes fruits, dietary fiber and plant extract, and has the effects of rich nutrition, appetite suppression, enhancing satiety, loosening bowel to relieve constipation, blocking absorption of carbohydrates and fat, and controlling weight.
17. Bifidobacterium pseudocatenulatum Strains with Genomic Variations in Carbohydrate Metabolism
PERFECT (CHINA) CO., LTD., 2023
Novel Bifidobacterium pseudocatenulatum strains PERFECT-2017-0001 and PERFECT-2017-0002, and compositions containing them, for treating obesity, metabolic syndrome, and related conditions. These strains were isolated from a genetically obese child who lost weight and improved clinical markers after consuming a diet enriched with non-digestible carbohydrates. The strains have specific genomic variations related to carbohydrate metabolism that likely contributed their competitive advantage in the changed dietary environment.
18. Probiotic and Nutritional Composition with Specific Bacterial Strains and Prebiotic Integration
WUHAN MIHUAN HEALTH IND DEVELOPMENT CO LTD, WUHAN MIHUAN HEALTH INDUSTRY DEVELOPMENT CO LTD, 2023
A probiotic composition and nutritional composition that can regulate metabolism and improve health. The probiotic composition contains specific strains of bacteria that promote a healthy gut microbiome. The composition includes bifidobacteria, lactobacilli, and other strains. The nutritional composition contains the probiotic composition and other ingredients like prebiotics and proteins. The combination of the probiotic and other ingredients can improve metabolism, reduce body weight, and improve skin health.
19. Bile Acid Composite Bacterial Agent Comprising Parabacteroides Distasonis Suspension
Shandong Longchang Animal Health Product Co., Ltd., 2023
Using a Parabacteroides distasonis bacterial suspension and bile acid to create a feed additive that can be given to mutton sheep to improve their quality. The bile acid composite bacterial agent is prepared by combining a bile acid with a bacterial suspension of Parabacteroides distasonis.
20. Lactobacillus rhamnosus Strain LM1019 with Inhibition of Adipocyte Differentiation and Lipid Accumulation
Genome and Company, 2023
Strain of Lactobacillus rhamnosus bacteria that can prevent and treat obesity and diabetes. The strain, called LM1019, inhibits fat cell differentiation and accumulation, reduces appetite, regulates lipid metabolism, and improves glucose metabolism. Administering LM1019 reduced weight gain, body fat, liver fat, blood glucose, insulin, cholesterol, and markers of obesity and diabetes in animal tests.
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