Probiotics for Anti-Aging Benefits

Compositions and methods for promoting cellular repair and glutathione synthesis to treat disorders related to aging, obesity, and COVID-19 infection. The compositions include at least one NMDAR modulator to modulate metabolic activity in cells and at least one NRF2 modulator to modulate anti-oxidation defense and repair activity in cells. The composition synergistically modulates a positive-feedback signal-amplification loop between NMDAR and NRF2, which promotes cellular metabolic fitness (CMF) activities.

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Using a specific bacterial strain called Dubosiella newyorkensis to extend lifespan and improve healthspan in living organisms. The bacteria was found to prolong the lifespan of worms called Caenorhabditis elegans by up to 20%. The bacteria was also found to improve the worms' health as they aged. The bacteria achieved this by regulating metabolism, improving intestinal immunity, and promoting resistance to inflammatory diseases.

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A strain of Lactobacillus plantarum bacteria, Lactiplantibacillus plantarum CCFM1291, that can convert ellagitannins from pomegranates and other sources into the anti-aging compound urolithin A. This strain can be used to produce fermented products rich in urolithin A. The fermented products, as well as synbiotic preparations containing the bacteria and ellagitannin-rich foods, can slow aging and extend lifespan in animals. The products also improve movement ability and mitochondrial function.

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Isolating and characterizing a strain of Pediococcus pentosaceus bacteria from human feces that has multiple probiotic functions like producing hyaluronic acid and glutathione. The strain KS5 has applications in preparing antioxidant and anti-aging foods and drugs due to its ability to secrete hyaluronic acid for anti-aging and wrinkle smoothing, and glutathione for antioxidant and detoxification benefits.

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A specific strain of Lactobacillus casei bacteria that exhibits enhanced anti-aging effects. The strain is identified as Lactobacillus casei JCM5826. It has been shown to reduce inflammation and improve cognitive function in aged mice. The strain can be used in anti-aging drugs and supplements at a concentration of 58-109 colony forming units (CFU) per milliliter.

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Improves immunity, resists oxidation and resists aging. The composition contains lactobacillus rhamnosus strain, which has excellent performances in improving immunity, resisting oxidation and resisting aging.

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Anti-aging, oxidization and inflammation. The product contains bifidobacterium adolescentis BA-3, which is deposited in China general microbiological culture Collection center (CGMCC, address: north Chen West Lu No.

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A new Streptococcus infantis strain, KCCM12642P, isolated from human skin, that improves skin health and reduces signs of aging like wrinkles, dryness and loss of elasticity. The strain, lysate or culture product can be used in cosmetics, creams or lotions to moisturize, strengthen the skin barrier, enhance elasticity and reduce aging.

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A plant fermented product containing koji mold, yeast, and lactic acid bacteria fermented from grains, fruits, vegetables, seaweed, seeds, and mushrooms as an active ingredient. The fermented product is designed to improve quality of life across a wide range of factors when consumed in food or drink form. It was developed as a comprehensive QOL booster to address age-related decline and improve overall well-being.

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Lactic acid bacteria strain Lactobacillus plantarum GKM3 for promoting longevity. The bacteria strain increases expression of the Cisd2 gene, which is linked to aging. Feeding mice this strain improves muscle strength, prevents muscle atrophy, delays neurodegeneration, and enhances learning and memory. The active substance from the bacteria can be used to develop products that promote longevity by increasing Cisd2 gene expression.

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Active substance of lactic acid bacteria, like Lactobacillus paracasei GKS6, that promotes longevity by increasing expression of the Cisd2 gene. Cisd2 is a gene involved in mitochondrial function and associated with aging. Administering compositions containing the lactic acid bacteria to recipients can delay neurodegeneration, muscle atrophy, and other aging phenomena by increasing Cisd2 expression.

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Composition comprising bacteria of the genus Akkermansia or its culture or treated products for preventing, improving and/or treating mitochondrial dysfunction, muscle inflammation, muscular atrophy and aging. The Akkermansia compositions improve mitochondrial function, suppress muscle inflammation, prevent muscular atrophy and have an anti-aging effect.

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Microbial compositions and strains for treating frailty and inflammation associated with aging. The compositions contain specific bacterial species that are inversely correlated with frailty and inflammation in older people. The species include Coprococcus catus, Eubacterium rectale, Alistipes putredinis, Barnesiella intestinihominis, Roseburia hominis, and Dorea longicatena.

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An anti-aging composition and method that uses isolated lactic acid bacterial strains to prevent aging. The composition includes lactic acid bacterial strains like Bifidobacterium bifidum, Bifidobacterium breve, and Bifidobacterium longum, as well as their fermented products. These strains can scavenge free radicals, inhibit P21 gene expression, reduce protein carbonyl levels, and enhance catalase activity to prevent aging when administered to subjects.

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An anti-aging composition containing lactic acid bacterial strains like Bifidobacterium bifidum, Bifidobacterium breve, and Bifidobacterium longum to prevent aging. The strains can be administered as isolated bacteria or fermented products. They scavenge free radicals, inhibit aging genes, reduce oxidative damage, and enhance antioxidant enzymes. Administering the composition at 106-1010 CFU/kg body weight daily can prevent aging.

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A food product to boost spermidine levels in the body for health benefits like increased longevity. The product is derived from fruits, vegetables, legumes, and grains that naturally contain spermidine. It is supplemented with extra spermidine, spermine, and/or spermidine-boosting agents like probiotics or spermidine precursors.

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A strain of Lactobacillus plantarum that improves the motor ability of aging organisms by reducing oxidative stress and inflammation. The strain is isolated from yogurt and identified by gram staining and DNA sequencing. It is found to have antioxidant properties and can improve exercise endurance, muscle and liver damage, and oxidative stress in mice. The strain is preserved in a microorganism center and can be used in food or supplements to improve motor function in aging individuals.

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A composite probiotic with functions of delaying senescence and resisting oxidation. The probiotic is made by combining three strains: Lactobacillus fermentum, bacillus coagulans, and Lactobacillus gasseri. The combination improves the antioxidant capacity of the probiotic compared to using any one strain alone.

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Combination therapy using a strain of the genus Lactobacillus and herbal medicines for preventing, improving, or treating aging-related diseases. The therapy involves administering a composition containing a Lactobacillus strain like Lactobacillus sake, Lactobacillus acidophilus, or Bifidobacterium animalis lactis, along with herbal medicines like yam, adlay, red ginseng, ganoderma lucidum, and vitamins like inulin and vitamins B and C. This combination has been shown to improve muscle strength, mitigate intestinal microbiome changes, and prevent obesity in aged mice.

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Anti-aging or antioxidant composition that suppresses the symptoms of muscle weakness induced by aging or reducing the change in the intestinal microbial environment induced by aging. The composition comprises a strain of the genus Lactobacillus and herbal medicine are co-administered.

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