Probiotic Support for Brain Health

A nano-armored single cell product for treating Parkinson's disease that encapsulates probiotic bacteria producing gamma-aminobutyric acid (GABA) inside liposomes. The liposome coating protects the bacteria from stomach acid and enzymes during oral ingestion. Once in the intestines, the liposomes break down and release the bacteria to produce GABA that can be absorbed into the bloodstream and cross the blood-brain barrier to potentially alleviate Parkinson's symptoms.

Source

Treatment of amyloidosis such as Alzheimer's disease with probiotic bacteria preferably in combination with cannabinoids and/or curcuminoids. The probiotic bacteria alone show therapeutic activity.

Source

Using a specific strain of lactobacillus bacteria, Lactobacillus mucilaginosus DACN8320, to prevent and treat neurodegenerative diseases like cognitive impairment from sleep deprivation. The strain has properties like acid resistance, bile tolerance, antioxidant activity, and intestinal barrier improvement. Supplementing the strain in mice with sleep deprivation improved cognitive function, intestinal health, reduced inflammation, and protected the blood-brain barrier.

Source

Compositions, systems, and methods for treating or preventing brain disorders like neuroinflammation, neurological disorders, neuropsychiatric disorders, and behavioral disorders by targeting the gut microbiota. The treatment involves administering a composition containing a prebiotic like green banana flour and psychobiotics like Lactobacillus reuteri and Lactobacillus plantarum. This aims to modulate the gut microbiota to protect against brain disorders by providing the bacteria with a food source and improving gut health.

Source

Using specific strains of bacteria, like Bifidobacterium bifidum, Bifidobacterium longum, and Lactobacillus paracasei, to improve mood disorders and cognitive function. The bacteria strains can be used in supplements for treating brain disorders like anxiety, depression, and dementia. The strains can also be used to improve cognitive function and prevent cognitive decline. The supplements can contain the strains alone or in combinations. The bacteria strains may be lyophilized for convenient dosing.

Source

Composition containing Lactobacillus fermentum strain SRK414 (accession number KCTC13687BP) for preventing, improving or treating cognitive dysfunction and Alzheimer's disease. The composition can be a pharmaceutical or food product. The SRK414 strain inhibits brain amyloid beta and tau protein production. It also alters gut microbiota composition compared to controls, with increases in Eubacterium xylanophilum, Ruminococcaceae, Alloprevotella, and decreases in Peptococcaceae, Lachnospiraceae NK4A136 group, Clostridia, Staphylococcus.

Source

Using Bifidobacterium longum subspecies i772 to improve cognitive function. The invention involves applying Bifidobacterium longum subspecies i772 to improve cognitive function. The strain has been found to significantly improve cognitive function in zebrafish models. The strain can be used to prepare cognitive-enhancing products like milk powder and yogurt. It provides a new application of Bifidobacterium longum to broaden its use beyond digestive health.

Source

Using the PS128 probiotic strain to treat Aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency causes problems in coordinating movements, hypotonia, and muscle stiffness due to inadequate neurotransmitter production. Administering PS128 to AADC deficient subjects increases neurotransmitter levels and improves motor activity, neuron branching, and AADC symptoms like sweating, dystonia, irritability and sleep disturbance.

Source

Using the probiotic bacteria Lacticaseibacillus paracasei to prevent or treat cognitive impairments induced by sleep deprivation. The bacteria can be used alone or in mixtures to provide cognitive benefits in subjects with sleep deprivation-related impairments.

Source

Alzheimer's disease prevention or treatment composition containing Lactobacillus sakei Probio-65 to alleviate Alzheimer's disease through changes in the profile of intestinal microorganisms and intestinal metabolome composition without side effects.

Source

Probiotic composition for improving memory and learning ability. The composition includes two microbial strains of Lactobacillus acidophilus, one of which is rhamnosus, and the other is a gram-positive bacilli, and a component that contains the compounds doxycycline, linomycin, and nitric acid.

Source

Composition for preventing, ameliorating or treating a brain disease, which contains Pediococcus inopinatus or a culture, a lysate, an extract or a fermented product thereof; or extracellular vesicles derived from the Pediococcus inopinatus, a culture or the lysate, extract or fermented product thereof; as an active ingredient. The composition can inhibit neuroinflammation, reduce cell death caused by oxidative stress and Aβ accumulation or inhibit the activity of acetylcholinesterase.

Source

Probiotic composition of Lactobacillus acidophilus GMNL-185 and Lactobacillus rhamnosus GMNL-680 that improve memory and learning ability. The ratio of GMNL-185 to GMNL-680 is 1:1. These specific strains were screened for their efficacy in enhancing fruit fly learning and memory, and provide a probiotic solution for improving cognitive function.

Source

Compositions comprising bacterial strains for treating neurodegenerative diseases. The strains are isolated from the mammalian digestive tract and include Megasphaera species like Megasphaera massiliensis. The compositions can prevent or delay onset and progression of neurodegenerative disorders like Parkinson’s, Alzheimer’s, and multiple sclerosis. The bacterial strains reduce inflammation, oxidative stress, and cell death, while promoting neurogenesis, neuritogenesis, and myelination. The strains can be administered as probiotics, food products, vaccines, or therapeutic compositions.

Source

Probiotic composition for improving the behavior of mother and offspring autism depression. The composition comprises a number of bifidobacterium animalis, a lactobacillus rhamnosus, 5-15 parts of stachyose, 10-40 parts of fructo-oligosaccharide, 1-5 parts of bacillus coagulans, 10-25 parts of acetylated distarch adipate and polydextrose.

Source

Probiotic Bifidobacterium strain for reducing stress and improving coping skills, vitality, and mental well-being in humans. The Bifidobacterium longum strain NCIMB 41676 showed efficacy in counter-regulating social stress and improving mental resilience.

Source

Genetically engineering Bacteroides ovatus and Lactobacillus plantarum to reduce the production of 4-ethylphenol and 4-ethylphenyl sulfate in the gut. These bacterial metabolites have been linked to anxiety and autism symptoms. By lowering their levels, the composition could alleviate or prevent anxiety and ASD in subjects. The genetically modified bacteria can be administered as probiotics along with polyphenols like quercetin or curcumin.

Source

A composition for preventing, treating, or improving neurological disorders, mental disorders, and senescence. The composition contains vesicles derived from Lactobacillus paracasei bacteria. The vesicles are isolated from cultures or fermented foods of Lactobacillus paracasei and can be formulated into pharmaceuticals, foods, inhalables, etc.

Source

Probiotic supplement to alleviate autism depression that contains specific strains of probiotics, prebiotics, and vitamins. The probiotics include Bifidobacterium adolescentis, Bacillus coagulans, Bifidobacterium breve, Bifidobacterium infantis, Bifidobacterium longum, Lactobacillus casei, Lactobacillus helveticus, Lactobacillus paracasei, Lactobacillus plantarum, Lactobacillus rhamnosus, and Lactobacillus salivarius. The prebiotics are fructo-oligosaccharide, lactitol, and arabinose. The vitamins are B6 and B9. The supplement provides high live bacterial count (10 billion

Source

Adjusting gut microbiota composition to treat neurodegenerative disorders like Parkinson's disease. This is done by administering antibiotics or microbial inhibitors to optimize the gut bacteria. This can improve motor function and reduce α-synuclein aggregation and neuroinflammation. The method exploits the gut-brain axis via the microbiota's influence on neurodevelopment and immune function. The goal is to restore gut microbial balance to alleviate neurodegeneration.

Source