Probiotics for Dental Health

Probiotic composition for oral health. The composition includes a strain of Streptococcus salivarius bacteria, isolated from the oral cavity, that has antimicrobial activity against caries-causing Streptococcus mutans. The strain produces a novel lantibiotic bacteriocin called SalE4. The composition also includes the isolated lantibiotic peptides, individually or as a multi-peptide protein.

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Using bacteria to treat periodontal disease. The bacteria Lactobacillus delbrueckii has been found to inhibit growth of the periodontal pathogen Porphyromonas gingivalis. The inhibitory effect is due to an enzyme called pyruvate oxidase that produces hydrogen peroxide. This specific L. delbrueckii strain or its pyruvate oxidase could be used as a probiotic to prevent or treat periodontal disease.

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Probiotic strain Lactobacillus helveticus K6 and compositions containing it for improving oral health. The strain inhibits oral pathogens like Streptococcus mutans and Porphyromonas gingivalis, prevents dental caries and gum disease, improves oral hygiene, and reduces bad breath. The strain can be used alone or in combination with other probiotics to make oral care products like mouthwashes, toothpastes, supplements, and foods. The strain can also be fermented with traditional Chinese medicines to create oral health products. The fermentation process involves inoculating the strain into a Chinese herbal extract, culturing it anaerobically, and harvesting the resulting probiotic ferment.

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Saliva combined lactobacillus strain, Ligilactobacillus salivarius Lsali-3, and applications for improving oral health. The strain is isolated from saliva and shown to have benefits like inhibiting oral pathogens, reducing inflammation, and preventing oral diseases like caries, periodontitis, and halitosis. The strain can be used in oral health products like foods, supplements, and mouthwashes to promote oral health. The strain's ability to coaggregate with oral pathogens suggests it could also be used as a probiotic therapy to displace pathogens and restore oral microbiome balance.

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Lactobacillus johnsonii strain for improving oral health. The strain, designated Ljohn-2, has beneficial properties for preventing and treating oral diseases like dental caries, periodontal disease, and bad breath. Ljohn-2 inhibits oral pathogens like Streptococcus mutans, Fusobacterium nucleatum, and Porphyromonas gingivalis. It also co-aggregates with these bacteria and has anti-inflammatory effects. The strain can be used in oral care products like mouthwashes, toothpastes, and chewing gum to prevent and treat oral diseases.

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Compound probiotic formula for reducing gingivitis that contains Lactobacillus plantarum N13, Lactobacillus acidophilus LA85, and Lactobacillus paracasei LC86 strains. These inactivated probiotics synergize to significantly reduce gingival redness and swelling as well as gingival sulcus depth. Using all three strains together provides a better effect than any single strain for alleviating gingivitis. This compound probiotic formulation can be applied in products like toothpaste to prevent or treat gingivitis.

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Lactobacillus pentosus NK357 and Bifidobacterium bifidum NK391 strains isolated from kimchi and human feces that have beneficial effects on preventing and treating inflammatory diseases like periodontitis and neuroinflammation caused by periodontitis. They also improve cognitive function. The strains can be used as active ingredients in pharmaceuticals to prevent or treat inflammatory diseases and cognitive impairment, as well as in functional foods to prevent or improve periodontitis and cognitive dysfunction.

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Oral hygiene composition containing probiotics and prebiotics to promote oral health and overall well-being. The composition can be in the form of toothpaste, mouthwash, chewing gum, spray, or frozen formulation. It contains strains like Bifidobacterium, Lactobacillus, and Streptococcus probiotics, along with prebiotics like fructo-oligosaccharides and galacto-oligosaccharides. Applying the composition to the oral cavity exposes the oral mucosa to the beneficial bacteria and prebiotic fibers to promote a healthy oral flora and fauna.

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Compositions containing specific strains of oral probiotics for improving oral hygiene, preventing cavities, and treating gum diseases. The compositions contain probiotics like Lactobacillus helveticus, Lactobacillus reticulatus, and Bifidobacterium longum that have synergistic antagonistic effects against oral pathogens like Streptococcus mutans. The probiotics can be used to prevent cavities, treat gum diseases, and improve oral hygiene when administered orally.

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Lactobacillus paracasei strain Probio-01 for preparing probiotic oral preparations that regulate oral flora balance and alleviate gum inflammation. The strain, inactivated forms, and metabolites can be used in oral preparations like toothpaste to inhibit pathogenic oral bacteria, increase beneficial bacteria, and improve oral health. The strain's ability to modulate oral flora and combat gum inflammation was demonstrated in mice and clinical trials.

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Composition and health functional food containing the Bifidobacterium breve IDCC 4401 strain, which has the ability to prevent gum disease and inhibit bad breath production. The composition can be used in foods, beverages, supplements, and pharmaceuticals. Bifidobacterium breve IDCC 4401 strain, isolated from breastfed infant stool, has properties like preventing oral pathogen adhesion, suppressing volatile sulfur compound production, and antioxidant activity. Adding this strain to oral care products, foods, or supplements can help prevent cavities, gingivitis, and bad breath.

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Composition for improving oral health containing live and dead lactic acid bacteria as active ingredients. The composition contains both live and dead lactic acid bacteria strains like Lactobacillus rhamnosus, Lactobacillus sakei, and Lactobacillus gasseri. The dead bacteria cells suppress harmful oral bacteria and the live bacteria further enhance oral health by increasing beneficial bacteria. This balanced combination of live and dead bacteria provides a more effective oral health improvement compared to using live bacteria alone.

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A strain of Lactobacillus sakei named MS103 with antioxidant effects and potential cavity probiotic functions. It can inhibit the pathogenic bacteria Porphyromonas gingivalis, which causes periodontitis. The MS103 strain can also interact with P. gingivalis, inhibit its biofilm formation, and potentially prevent periodontal diseases. The strain can be used to develop oral care products, health supplements, medications, and foods that combat P. gingivalis.

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Mouthwash containing inactivated probiotic strains to improve oral health. The mouthwash includes powdered inactivated strains of Lactobacillus johnsonii, Lactobacillus salivarius, Lactobacillus acidophilus, and Lactobacillus plantarum in specific ratios. It also contains functional additives, anti-inflammatory agents, foaming agents, sweeteners, menthol, and water. The inactivated probiotics provide oral health benefits without requiring live bacteria. The mouthwash can be made by combining the inactivated powdered strains with other ingredients in specific amounts.

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A novel oral probiotic strain, Lactobacillus reuteri TSB-R7, that is resistant to high concentrations of propolis. This strain has potential for use in oral care products containing propolis, as it can survive and establish in the oral cavity when used in oral care products using propolis. The strain also has antibacterial activity against cavity-causing bacteria like Streptococcus mutans. The combination of propolis and Lactobacillus reuteri TSB-R7 has synergistic antibacterial effects against Streptococcus mutans.

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Composite probiotic metazoan composition for preventing or treating dental calculus and application thereof. The composition comprises lactobacillus casei Zhang (Lactobacillus casei Zhang), bifidobacterium animalis subspecies V9 (Bifidobacterium animalis subsp.lactis V9) are preserved in the China general microbiological culture Collection center (CGMCC) with the preservation number of CGMCC No.5469; and lactobacillus plantarum P-8 (Lactobacillus plantarum P-8) which is preserved in China general microbiological culture Collection center with a preservation number of CGMCC No.6312.

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Bacillus subtilis strain ID-A05 for preventing and treating cavities, periodontal diseases, and halitosis. The strain ID-A05 can be used in compositions like toothpaste, mouthwash, and gargle to prevent and improve oral health.

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Lactobacillus anhydrous dental tablet containing live bacteria that can survive and activate in the dry oral environment. The tablet contains lactobacillus strains, nutrients, acids, binder, lubricant, flavor, and sweeteners in specific proportions. The anhydrous system allows the live bacteria to remain dormant until they encounter moisture in the mouth. This prevents loss of efficacy when brushing with water. The lactobacillus strains inhibit oral pathogens and restore oral microbiome balance for deodorizing and fresh breath.

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Novel Bacillus velezensis strains and their use as oral care products to treat cavities, periodontal diseases, and halitosis. The strains are cultured to produce a supernatant that can be used in toothpaste, mouthwash, or food products. The strains and supernatant inhibit growth of bacteria causing oral diseases like cavities and gum inflammation, while also reducing halitosis.

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Probiotics and biological preparations containing the strain Lactobacillus reuteri LR-G100 for alleviating traumatic oral lesions caused by orthodontic appliances. The probiotics can reduce pain and speed healing of oral wounds from brackets and wires. The LR-G100 strain is effective in benefiting oral health during orthodontic treatment.

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