Probiotics for Mood and Anxiety Support

Using specific strains of bacteria, like Bifidobacterium bifidum, Bifidobacterium longum, and Lactobacillus paracasei, to improve mood disorders and cognitive function. The bacteria strains can be used in supplements for treating brain disorders like anxiety, depression, and dementia. The strains can also be used to improve cognitive function and prevent cognitive decline. The supplements can contain the strains alone or in combinations. The bacteria strains may be lyophilized for convenient dosing.

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Nutrient composition for improving brain health and reducing neurological disorders like anxiety, oxidative stress, memory issues, and nerve protection. The composition contains specific natural compounds like stachyose, lactobacillus plantarum, walnut peptide, cistanche deserticola, casein hydrolysate, and theanine.

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Probiotic compositions for preventing and treating stress-related conditions like impaired cognitive function, anxiety, insomnia, baby blues, postpartum depression, menopausal depression, generalized anxiety disorder, major depressive disorder, panic attacks, attention deficit disorder. The compositions contain a combination of probiotic strains, Lactobacillus reuteri PBS072 and Bifidobacterium breve BB077 or Bifidobacterium lactis BL050.

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Lactobacillus brevis KU15152 strain, isolated from kimchi, for preventing or treating neurodegenerative diseases like Alzheimer's, Parkinson's, and depression. The strain has a protective effect against nerve cell death caused by oxidative stress. The protection is due to metabolites produced when the strain interacts with intestinal cells. The strain, dead cells, and metabolites can be used in pharmaceuticals, health supplements, and probiotics to prevent/treat neurodegenerative diseases and depression.

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Preventing or treating depression containing Lactobacillus Buchneri 200793 strain (KCCM 12593P) or a culture of the strain as an active ingredient. The composition includes live or dead cells of the strain, a concentration of 10 8 to 10 11 CFU/ml, preferably at a concentration of 10 10 CFU/ml, and a human feed additive composition for preventing or improving depression.

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Probiotic composition for treating depression with diarrhea-predominant irritable bowel syndrome (IBS-D). The composition contains specific strains of Bifidobacterium lactis, Lactobacillus paracasei, Lactobacillus rhamnosus, Bifidobacterium longum, Lactobacillus plantarum, and Lactobacillus acidophilus. These strains were found to effectively relieve depressive symptoms and diarrhea in people with depression and IBS-D compared to placebo.

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An oral composition containing S-adenosyl methionine (SAMe) and probiotics for treating and preventing mood disorders like anxiety and depression. The composition can be in stable solid forms like orosoluble granulates or tablets. The composition improves patient adherence to therapy by combining the mood regulating SAMe with live probiotics that reach the gut intact.

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Compositions containing specific lactic acid bacteria strains for treating or preventing conditions related to the nervous system or body. The bacteria strains contain compounds like catechols, guaiacols, and 4-methoxyphenols that increase proliferation. This provides a natural approach to support mental development, memory, and alleviate disorders like anxiety, depression, and eating disorders. The bacteria strains are from lactic acid bacteria genera like Lactobacillus, Lacticaseibacillus, and Lactipplantibacillus.

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Composition and agents containing Lactobacillus paracasei to suppress and improve depression. Lactobacillus paracasei strain KW3110 was found to effectively suppress and improve depression when ingested. The strain can be used in a composition, agent, or method for depression relief.

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Synbiotic composition containing specific bacterial strains and dietary fibers for treating neuropsychiatric disorders like ADHD, OCD, and borderline personality disorder. The synbiotic contains two or more strains from Lactobacillus plantarum, Lactobacillus paracasei, Pediococcus pentosaceus, Leuconostoc mesenteroides, and Bifidobacterium breve. The fibers include inulin, pectin, beta-glucan, resistant starch, galacto-oligosaccharides, and isomalto-oligosaccharides. The total bacterial dose is 10^6-10^13 CFU and fiber dose is 0.1-20 g. The synbiotic aims to improve symptoms of neuropsychiatric disorders and reduce side effects of pharm

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A compound nutritional composition for relieving depression-like symptoms in mammals that combines probiotics, prebiotics, and specific nutrients. The probiotics include strains like Bifidobacterium longum, Lactobacillus casei, Lactobacillus rhamnosus, and Lactococcus lactis. The nutrients include folic acid, vitamin B12, selenium, iron, and zinc. The prebiotics are fructo-oligosaccharides and galacto-oligosaccharides.

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Preventing or improving stress-related diseases like anxiety and depression using a specific strain of probiotic bacteria. The strain is Lactobacillus rhamnosus 4B15 (Lacticaseibacillus rhamnosus 4B15) and compositions containing this strain. The strain reduces symptoms of chronic stress like anxiety and depression, neurodegeneration, inflammation, and blood-brain barrier dysfunction in animal models. It does this by modulating genes and proteins related to stress response, neuroinflammation, blood-brain barrier function, and neurodegeneration.

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Composition of probiotic strains for improving anxiety caused by antibiotics. The composition includes Lactobacillus plantarum GMNL-141, Lactobacillus rhamnosus GM-020, and Lactobacillus acidophilus GMNL-185 strains. These probiotics can be used to prepare pharmaceutical compositions, foods, or supplements to mitigate anxiety associated with antibiotic use.

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Composition containing Lactobacillus paracasei (Lparacasei) to suppress and/or improve depression. The composition can be used as a dietary supplement or food ingredient to alleviate depression symptoms. The specific Lparacasei strain used is KW3110. It was found that ingesting KW3110 strain improved depression levels, particularly before workloads, suggesting it could be used to manage daily life stress.

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Compositions for promoting the neurological health, psychological health or brain health of an individual to treat behavioral or neurological disorders. The compositions contain specific bacterial metabolites, such as phenyl sulfate, pyrocatechol sulfate, 3-(3-sulfooxyphenyl)propanoic acid, and indoxyl sulfate, or bacteria that produce these metabolites. The bacterial metabolites can be formulated as dietary supplements, probiotics or pharmaceuticals to restore normal brain function and behavior in conditions like anxiety disorders.

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Probiotic composition for relieving anxiety or depression. The composition includes prebiotics, a K-KLJ probiotic combination comprising at least one of lactobacillus plantarum, lactobacillus reuteri, lactobacillus casei, lactobacillus helveticus and a functional substance.

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Probiotic formulation to reduce stress and anxiety. The formulation contains a consortium of probiotic microbes, including Bacillus coagulans, Lactobacillus rhamnosus, Bifidobacterium lactis, Lactobacillus plantarum, Bifidobacterium breve and Bifidobacterium infantis. The probiotic microbes produce neurotransmitters like GABA when metabolizing glutamine in the gut. This inhibitory neurotransmitter helps to reduce stress and anxiety when it reaches the brain.

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A lactic acid bacterium, Lactobacillus delbrueckii subspecies lactis, or a lactic acid bacterium-derived ingredient therefrom, as an active ingredient for preventing, treating or ameliorating stress disorders. This bacterial ingredient can be formulated into a composition with additional ingredients like water-soluble dietary fibers to enhance the effect.

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Composition containing lactic acid bacteria strains and their metabolites to improve brain function. The strains, like Lactobacillus salivarius and Bifidobacterium longum, and their fermentation products can elevate brain function when consumed. The composition can be used as a food or pharmaceutical to boost brain ability.

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A composition containing specific probiotic strains for preventing and treating anxiety disorders and related conditions in mammals like humans, particularly pregnant women, lactating women, and infants. The composition contains probiotics like Lactococcus lactis or a combination of Bifidobacterium longum and Lactobacillus rhamnosus to prevent and treat anxiety disorders. The probiotics are added to nutritional products like infant formula, breast milk substitutes, and baby foods. They can be administered during pregnancy, breastfeeding, or infancy to provide neurodevelopmental benefits for anxiety prevention and treatment.

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Using bacterial compositions to modulate serotonin levels in the gut to treat serotonin-related disorders. Some bacteria can produce serotonin or compounds that increase serotonin production. These bacteria, when ingested or administered, colonize the gut and increase serotonin levels. The compositions can include live bacteria species that produce serotonin, as well as dead bacteria, bacterial cell pellets, conditioned medium, or purified bacterial metabolites and proteins that modulate serotonin.

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Probiotic composition containing specific strains of lactobacillus, bifidobacterium, and paracasei bacteria that can prevent the formation of depression and anxiety behaviors. The composition includes lactobacillus plantarum Lp3a, lactobacillus paracasei LPC45, and bifidobacterium breve BB033 in specific ratios. The bacteria strains have beneficial properties like acid and bile resistance, production of neurotransmitters, and vitamin K synthesis that can improve gut health and prevent depression and anxiety.

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Using human milk oligosaccharides to treat mood and emotion disorders like anxiety and depression by altering the gut microbiota to reduce inflammation and improve gut barrier function. The method involves using specific neutral human milk oligosaccharides that can increase bifidobacteria abundance to influence neurotransmission regions involved in emotions.

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Composition containing probiotics and folic acid for alleviating mood swings. The composition contains probiotics like Lactobacillus rhamnosus, Bifidobacterium longum, Bacteroides fragilis, and Lactobacillus acidophilus along with folic acid. It also includes adjuvants like maltitol, maltodextrin, water-soluble dietary fibers, and stevioside. The composition is used to regulate mood swings by altering gut bacteria and vitamin levels.

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Increasing vigour in humans by administering strains of Lactobacillus plantarum, such as DSM 9843 (299v). Vigour is enhanced by at least 3.5 points on the Profile of Mood States (POMS) scale after 12 weeks of supplementation with the Lactobacillus strain.

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The use of specific strains of Lactobacillus bacteria to reduce and/or prevent deleterious effects of acute psychosocial stress in humans. Administering the Lactobacillus strains via food or supplements reduces stress-induced inflammation and physiological responses compared to untreated individuals.

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Fermented milk containing specific Lactobacillus species for improving autonomic nervous system function. The fermented milk is made using Lactobacillus species like L. delbrueckii, bulgaricus, gasseri, rhamnosus, or acidophilus. Ingesting this fermented milk with the specific Lactobacillus strains reduces the relative sympathetic nerve activity index, improving autonomic nervous system function. This can benefit health and wellbeing.

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Mood-regulating probiotic composition containing a co-fermentation of Lactobacillus rhamnosus and Lactobacillus fermentum. The composition is made by jointly fermenting these two strains under anaerobic conditions. It has benefits like acid resistance, bile salt resistance, and intestinal colonization ability. This probiotic composition can be used to make products like foods, beverages, supplements, or medications to regulate mood and alleviate anxiety and depression.

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A composition for treating anxiety and mood disorders like depression. The composition contains glutamine, curcuma extract and Lactobacillus rhamnosus in specific proportions. The composition is used as a food supplement, nutraceutical or drug to prevent or treat anxiety and mood disorders. The specific combination of these three ingredients is found to have synergistic effects on mental well-being greater than each ingredient alone.

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Using a specific strain of probiotic bacteria, Lactobacillus rhamnosus CNCM I-3690, to prevent and treat anxiety and psychological stress. Administering an effective amount of the bacteria in a composition like a dairy product. The bacteria is consumed in doses of at least 10^8 to 10^14 colony forming units per day for at least a week to reduce stress levels.

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Using Lacticaseibacillus paracasei (formerly known as Lacticaseibacillus paracasei) bacteria to prevent and treat mental health symptoms and promote overall well-being in mammals. The bacteria can reduce the psychological and physiological effects of stress and prevent/treat mental health symptoms when administered to mammals.

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Preventing and treating cognitive dysfunction and depression using a specific strain of lactic acid bacteria, Lactobacillus casei HY2782. The composition contains the bacteria strain as an active ingredient. It increases brain nerve cell proliferation and reduces cell death, especially from stress hormones. This suggests the composition could improve conditions like dementia and depression by protecting brain cells. The composition can be delivered as pharmaceuticals, foods, or beverages.

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Using a specific strain of lactic acid bacteria, Lactobacillus plantarum HY7715, to prevent or treat cognitive dysfunction like dementia and depression. The bacteria increases brain cell proliferation, reduces apoptosis, and boosts neurotrophic factors like BDNF. This suggests it can improve brain health and potentially prevent or mitigate conditions like dementia and depression. The bacteria can be formulated into pharmaceuticals or foods for prevention/treatment.

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Using a Lactobacillus sakei strain, WIKIM31, for preventing and treating depression and anxiety. The strain is derived from kimchi and can alleviate depression and anxiety symptoms in mice. Administering the strain to mice increased movement and exploration compared to control groups.

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A composition of bacterial strains for use in treating mood disorders such as depression. The mixture contains specific strains of probiotic bacteria, vitamins, minerals, and other nutrients. It aims to improve mood, reduce anxiety, and optimize emotional state. The bacterial strains are S. thermophilus, L. plantarum, and B. breve. The composition also includes vitamins B, D, E, minerals magnesium, selenium, zinc, and antioxidants N-acetylcysteine, CoQ10, and acetyl-L-carnitine.

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Dysbiosis of the gut microbiome is associated with a range of disorders including CNS conditions like mood disorders, anxiety, autism and mental health disorders. The invention proposes treating these conditions by delivering bacteria or their products to correct the dysbiosis. Specifically, it involves using a targeted approach where specific heirloom bacterial strains are administered to restore missing or deficient functions in dysbiotic individuals. For example, providing bacteria that produce queuine to address queuine deficiency linked to CNS disorders.

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Composition containing Lactobacillus paracasei HP7 strain for preventing and treating cognitive dysfunction and depression. The composition can be a pharmaceutical or a food. The Lactobacillus paracasei HP7 strain increases brain cell proliferation and reduces apoptosis through BDNF expression. It also inhibits brain cell death by stress hormones. This composition is useful for improving cognitive function and depression.

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Composition containing Bifidobacterium animalis subspecies lactis strain HY8002 for preventing and treating cognitive dysfunction and depression. The composition can be in pharmaceutical or food form. The Bifidobacterium strain increases brain nerve cell activation gene BDNF and cell survival gene RELA expression to reduce brain cell death caused by stress hormones. This composition can be used to improve cognitive function and depression by mitigating brain cell proliferation and death.

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Probiotic bacteria Pediococcus acidilactici CCFM6432 for preventing and alleviating depression. The probiotic strain is able to regulate neurotransmitter levels in the brain and promote biosynthesis of neurotransmitter precursors. In animal studies, the probiotic reduced depression-like behaviors in stressed mice. Pediococcus acidilactici CCFM6432 is ingested as a probiotic or used as a drug to prevent or alleviate depression.

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Probiotic composition containing specific strains of Lactobacillus bacteria, as well as compounds like GABA, inulin, and Theanine, to improve mental stress relief and sleep. The probiotic strains are Lactobacillus brevis, Lactobacillus casei, Lacticaseibacillus paracasei, and Lactobacillus acidophilus. The composition aims to provide a synergistic blend of probiotics and compounds that can enhance the probiotic effects of relieving mental stress and improving sleep.

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Using the probiotic strain Lacticaseibacillus paracasei to alleviate psychological and physiological responses to stress, prevent/treat symptoms of mental health issues, and promote overall mental and physical well-being in mammals. The strain can be administered as a food supplement, dietary supplement, or pharmaceutical composition. It reduces stress-related physiological responses like increased heart rate, cortisol production, and blood pressure, as well as perceived fatigue. It also improves perceived health, productivity, and sleep quality during stressful periods.

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A strain of Lactobacillus sakei isolated from kimchi that has prophylactic, alleviating or therapeutic effects on depression and anxiety disorders. The strain is a Gram-positive, rod-shaped bacterium that can improve symptoms of depression and anxiety in mice models. Administering the strain to mice with induced depression or Parkinson's disease increased movement and reduced standstill time compared to controls. This suggests the strain can prevent or treat depression and anxiety disorders. The strain could be used in food or pharmaceutical compositions to prevent or treat depression and anxiety disorders.

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A probiotic composition for treating depression in people with comorbid constipation. The composition contains specific strains of bacteria: Bifidobacterium animalis subsp. lactis U9, Lactobacillus paracasei L55, Lactobacillus rhamnosus LL23, Bifidobacterium adolescentis BQ23, and Lactococcus acidophilus RA15. Administering this probiotic blend to depressed individuals with constipation improves their depression symptoms more effectively than a placebo. The composition can be used in drugs, food, or health supplements for treating comorbid depression and constipation.

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Using the probiotic Lactobacillus plantarum PS128 to prevent or treat abnormal emotions and behaviors in animals such as fears, phobias, anxieties, and aggression. Administering the probiotic to animals like dogs and cats to reduce abnormal behaviors and improve emotional well-being.

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Methods and compositions for treating depression, anxiety, and related disorders using orotic acid and probiotics. The methods involve administering effective amounts of orotic acid or a salt thereof and one or more probiotic microorganisms to a subject in need thereof. The compositions comprise orotic acid orotate and probiotics for treating and preventing depression, anxiety and depressive and anxiety-related disorders.

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Composition containing dead cells of specific Lactobacillus strains, Lactobacillus fermentum and Lactobacillus delbrueckii, for treating stress and anxiety disorders. The dead cells have neurosuppressive and neurostimulatory effects. They can be used to protect against stress-related conditions like depression, autism, PTSD, social dysfunction, fibromyalgia, compulsive behaviors, and irritable bowel syndrome. The cells modify intestinal microbiota and reduce harmful bacteria like Alistipes and Odoribacter.

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Using a specific strain of Lactobacillus brevis bacteria, Lactobacillus brevis TCI988, and its metabolites to develop compositions for neurological health, sleep aid and antidepressant, fat reduction applications. Lactobacillus brevis TCI988 has unique properties like producing GABA, promoting mitochondrial activity, enhancing melatonin synthesis genes, and reducing fat accumulation. These functions make TCI988 useful for compositions to address neurological issues, sleep disorders, and obesity.

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Probiotic composition to help reduce symptoms of depression and improve antidepressant efficacy while mitigating side effects. The composition contains specific strains of bacteria like Bifidobacterium longum, Lactobacillus helveticus, Lactobacillus rhamnosus, Lactobacillus acidophilus, Lactobacillus reuteri, and Clostridium butyricum. The ratios of these strains in the composition are optimized to provide therapeutic benefits for depression. The composition can be used as a supplement to antidepressant medication to enhance treatment outcomes and reduce side effects.

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Novel lactic acid bacteria strains, Lactobacillus mucose (NK41) and Bifidobacterium longum (NK46), that can prevent and treat memory disorders, learning disorders, and mental disorders. The bacteria inhibit expression of aging factor p16 protein and inflammatory factors. They also improve memory, anxiety, and depression in animal models. The lactic acid bacteria can be used to prevent and treat memory disorders, learning disorders, and mental disorders, as well as inflammatory diseases, due to their anti-aging, anti-inflammatory, and neuroprotective effects.

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Anti-stress composition containing Lactobacillus herbeticus bacteria to prevent, reduce, or suppress stress. The composition can be used as a pharmaceutical drug, food or drink supplement to treat anxiety, social phobia, social decline or adjustment disorders caused by stress. The Lactobacillus herbeticus strain is preferably NITE BP-01671. The bacteria can be cultured in a milk medium, dried and mixed with prebiotics to make anti-stress milk powder. Alternatively, prebiotics, bacteria and milk components are combined to make anti-stress supplements.

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