Package testing laboratories must verify compliance across multiple regulatory frameworks, from FDA 21 CFR for pharmaceutical packaging to UN 3480 for lithium battery transport. Current systems process thousands of samples daily, with testing cycles that can span 2-4 weeks per submission and require precise environmental control (±0.5°C temperature, ±2% relative humidity) throughout the evaluation period.

The core challenge lies in maintaining testing accuracy and documentation while processing high sample volumes under strict environmental parameters and varying regulatory requirements.

This page brings together solutions from recent research—including AI-driven verification systems with multilevel checks, blockchain-integrated monitoring platforms, and modular testing architectures that adapt to different material types. These and other approaches help testing facilities maintain compliance while improving throughput and documentation accuracy.

1. Blockchain-Integrated Food Packaging System with IoT Sensor Monitoring and Smart Contract Enforcement

BHARAT RAMDAS PAWAR, 2024

A blockchain-based food packaging system that uses smart contracts, IoT sensors, and blockchain to ensure nutritional integrity and compliance during food packaging. The system involves tracking environmental factors like temperature, humidity, and light exposure during packing using sensors. Smart contracts enforce nutritional standards. Blockchain records the data for transparency and traceability. This prevents nutrient degradation and ensures compliance. It also provides an auditable chain of custody for food safety. Consumers can scan QR codes to view blockchain records confirming nutritional value and compliance.

2. Pharmacy Packaging Verification System with Multilevel Barcode Scanning, Image Recognition, and Database Integration

GLA UNIVERSITY MATHURA, 2024

Verification system for pharmacy packaging that uses multiple levels of checks to ensure medication accuracy and safety during packaging. The system uses barcode scanning, image recognition, database integration, electronic prescription verification, dosage verification, drug interaction checking, allergy alerts, expiration date verification, tamper-evident packaging detection, and user authentication. It involves steps like offline coding, line check, packaging line, printed material store, online coding, return control, return to store.

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3. Compostable Packaging Film with Micro-Perforated Structure and Adjustable Oxygen Transmission Rate

FRESHR SUSTAINABLE TECH INC, 2024

Compostable film for packaging perishable items like seafood that has adjustable oxygen transmission rate (OTR) to meet regulatory requirements. The film has a micro-perforated structure with pores connecting the food and environment sides. A barrier coating on the external side covers the pores further adjusts OTR. The internal surface can be modified and coated with antimicrobials. This provides a compostable film with customizable oxygen and antimicrobial properties for food packaging.

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4. Pressurized Plastic Bottle with Differential Thickness Distribution for Enhanced Mechanical Strength

L'Oréal, 2024

A pressurized bottle with a container made of plastic material that meets regulatory requirements for aerosol bottles containing liquefied gases and compressed gases. The container has specific thickness dimensions in different parts to provide mechanical strength for testing without cracking or deformation. The thicknesses are: - Lower part: >1.1 mm (preferably >1.4 mm) - Middle part 1: >0.65 mm (preferably >0.9 mm) and >6 mm height - Middle part 2: >0.4 mm (preferably >0.6 mm) and >8 mm height - Middle part 3: >0.4 mm (preferably >0.6 mm) and >8 mm height - Bottom part: >0.6 mm This thickness distribution prevents bottle failure during tests for venting, vacuum, drop, water immersion

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5. System for Generating Packaging Material Certification Documents with Automated Information Retrieval and Compliance Verification

PPLUS CO LTD, 2023

Generating packaging material certification documents that meet requirements and legal standards according to the producer responsibility recycling system. The document generation includes receiving, by the certification document generating system, packaging information of the packaged product from the second terminal; and generating a certification document regarding the packaging material of the packaged product based on the packaging information.

6. Plastic Aerosol Bottle with Integrated Neck and Specified Wall Thickness for Pressure Resistance

LOREAL, 2022

A plastic aerosol bottle that meets regulatory requirements for liquefied gas aerosol products. The bottle has a container made of a specific type of plastic material and a unique neck design. The container is made of a plastic like PET, PEF, PC, PGM, PMMA, SAN, PBT, PA6, PA12, PEEK, PPG, or filled polymers with thickness of at least 0.9 mm in a specific area. The neck is also made of the same plastic and is one-piece with the body, with a thickness of at least 0.9 mm in a lower section at least 8 mm high starting 10-40% from the top. This design provides the needed strength and pressure resistance for liquefied gas aerosol bottles.

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7. Phase Change Composite Material with Recyclable Thermoplastic Polymer and Open-Pored Powder for Enhanced Dimensional Stability

BUSCH RAINER, 2022

A new type of phase change composite material (PCM-V) for packaging applications that can be recycled multiple times without losing performance. The PCM-V contains a phase change material (PCM) like calcium carbonate, along with other materials like open-pored powder and thermoplastic polymer. The composite has improved dimensional stability and leak-proofness compared to PCM alone. This allows recycling the PCM-V multiple times up to 80°C thermal stimulation without degradation. The composite is also recyclable as part of packaging waste, meeting the new European Packaging Directive requirements. The composite can be used in packaging applications like food containers, where the PCM provides temperature control, and the composite allows multiple recycling cycles.

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8. Blow-Fill-Seal Aseptic Packaging System for Low Acid Foods with Sterile Air Management and Surface Presterilization

MJN US HOLDINGS LLC, 2021

Aseptic packaging of low acid foods using blow-fill-seal technology that meets FDA requirements. The method involves forming and maintaining an aseptic work zone that allows blow-fill-seal machines to process low acid foods without an enclosed environment. The key steps are: 1) presterilizing critical surfaces like the parison and fill nozzle, 2) maintaining sterility with continuous HEPA-filtered air in the aseptic zone, 3) displacing sterile air from containers with the product to prevent contamination, and 4) continuously passing sterile gas through the parison to keep the open end sterile. This enables blow-fill-seal aseptic packaging of low acid foods in a non-enclosed machine.

9. Method for Determining Migration Potential of Printed Food Packaging Inks via Solvent Extraction and Spectroscopic Analysis

HUBERGROUP DEUTSCHLAND GMBH, 2021

Easy, time-efficient, and cost-efficient method to determine the migration potential of printed food packaging inks and varnishes to ensure compliance with legal limits. The method involves extracting migratable low molecular weight compounds from the printed packaging into a solvent, quantitatively measuring a spectroscopic characteristic like absorbance or transmittance of the extract, and comparing the measurement to a calibration curve correlating migration to spectroscopic values for the specific ink/varnish-substrate system. This allows precise and reliable migration determination without the risk of falsification from other ink components absorbing at the measurement wavelength. The spectroscopic characteristic measurement is at a wavelength where the value is at least 50% of the peak maximum.

10. Pressurized Aerosol Bottle with Variable Wall Thickness for Structural Integrity

OREAL, 2021

Pressurized plastic aerosol bottle design that meets regulatory requirements for containers holding liquefied or compressed gases. The bottle has a thicker base and sides compared to typical aerosol bottles. The container has a minimum thickness of 0.65mm in a lower section, 1.1mm at the base, and 0.6mm in upper sections. This provides the strength needed to pass testing without cracking. The thicker base prevents sagging and deformation during tests. The thicker walls also prevent inversion or deformation during hot and cold tests.

11. Food Packaging Standards for Plastics with Material Selection and Safety Specifications

RAHUL JAIN, 2020

The role of standards in food packaging, especially with regard to plastics, is to provide guidance on selecting suitable materials for food contact applications. It ensures that the plastics used are safe and do not pose any harm to human health or the environment. Standards also provide specifications for testing and evaluating the safety and suitability of plastics for food packaging. By adhering to these standards, food packagers can ensure that their packaging materials are safe for food contact and meet regulatory requirements.

12. Packaging System with Integrated Sealing, Printing, Weighing, and Inspection Devices for Post-Sealing Verification of Printed Product Information

MULTIVAC MARKING & INSPECTION GMBH & CO KG, 2020

Packaging system and method for verifying product information printed on packaging after sealing to ensure accuracy and compliance with guidelines for calibrated weighing and approved price labeling. The system has a sealing station, printing device, front weighing device, and inspection device downstream. The controller links the printing to the weighing so the printed info is based on the product weight. An inspection device reads the printed info to check for accuracy against the known weight.

13. Plastic Aerosol Bottle with Reinforced Neck Structure for High-Pressure Liquefied Gas Containment

OREAL, 2020

A plastic aerosol bottle that meets safety and regulatory requirements for storing liquefied gases like refrigerants in plastic containers. The bottle has a thickened neck region with a height of at least 8 mm, starting at 10-40% of the container's total height. This thickened neck section has a minimum thickness of 0.9 mm, providing increased strength to prevent container failure when subjected to the high pressures used for liquefied gases.

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14. Blow-Fill-Seal System for Aseptic Packaging of Low-Acid Foods with Pre-Sterilized Components and Continuous Sterile Gas Flow

MEAD JOHNSON NUTRITION CO, 2020

Aseptically packaging low-acid foods using blow-fill-seal technology in compliance with FDA regulations. The method involves pre-sterilizing critical components like fill nozzles and maintaining sterility during blow-fill cycles using HEPA-filtered air. This allows open areas like the shroud to be pre-sterilized with gas instead of being enclosed. Continuous sterile gas flow prevents contamination. The parison interior is sterilized with ballooning gas before cooling. Sterile air displaces product to maintain container sterility. This allows aseptic packaging without enclosed environments.

15. Laminate Medical Packaging Film with Potassium Ionomer Antistatic Layer

AICELLO CORP, 2020

A medical packaging film that can package and transport drugs without contamination. The film has a laminate of thermoplastic resin layers with a potassium ionomer layer in contact with the contents. The potassium ionomer layer provides antistatic properties while maintaining a low acid titer and ignition residue. The film can be used for large weight packaging of drugs and conforms to regulations for medical containers.

16. Inflatable Life Raft Enclosure with Multi-Layer Film Comprising Heat-Sealable and Fire-Retardant Layers

GOODRICH AEROSPACE SERVICES PRIVATE LTD, 2019

Packaged inflatable life raft for aircraft that reduces weight while meeting regulatory requirements for stowage and flammability. The life raft is enclosed in an enclosure with a specialized multi-layer film. The innermost layer closest to the life raft is heat-sealable polymer like PE, PP, or halogenated polymer. Outer layers have metal foil, vapor barrier, or fire retardant polymer like polyester/polyamide. This layer combination provides containment, flammability resistance, and weight savings compared to traditional enclosures.

17. Multi-Layer Medical Packaging Film with Potassium Ionomer-Containing Inner Layers for Antistatic Properties

AICELLO CORP, 2019

Medical packaging film with antistatic properties that meets regulatory requirements for packaging drugs and medicines. The film has a multi-layer structure where the innermost layer in contact with the contents and optionally an intermediate layer also contain a potassium ionomer. The outer layers don't contain the ionomer. This configuration maintains antistatic performance while avoiding excessive alkali content. The ionomer layers prevent dust explosion and reduce elutable alkali. The film meets alkali limits in European Pharmacopeia and has low ignition residue.

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18. Multilayer Barrier Laminate with Cyclic Olefin Resin Outer Layer and Low Melting Point Intermediate Layer

DIC CORP, 2019

Barrier laminate and packaging material that effectively suppresses elution of mineral oil, printing ink, and adhesive components into packaged foods. The laminate has a multilayer film structure with specific layers. The innermost layer seals the contents, an intermediate layer has lower melting point resin, and an outer layer has higher melting point cyclic olefin resin. A coating layer, adhesive, printing, or mineral oil layer is applied on top. This configuration allows thin films with good barrier properties, sealing strength, and mechanical integrity while suppressing elution of regulated substances like mineral oil, printing inks, and adhesives below safety limits.

19. Inflatable Life Raft Packaging with Multi-Layered Flammability-Resistant Film

GOODRICH CORP, 2018

Packaging for inflatable life rafts that meets flammability requirements and reduces weight compared to traditional life raft enclosures. The packaging uses a specialized film with layers of materials like heat-sealable polymer, vapor barriers, fire retardants, and metal foil to meet regulatory flammability standards. This allows a lightweight enclosure around the non-inflated life raft that provides protection and compliance without adding excessive weight.

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20. Blister Package with Integrated Wrap Featuring Human-Readable and Machine-Readable UDI Panels

CooperVision International Holding Company, LP, 2018

Packaging for individually wrapped contact lenses that provides both human-readable and machine-readable unique device identifiers (UDIs) on the package. The contact lens is sealed in a blister package with a printed UDI on the sealing member. A separate wrap with panels is attached to the sealed package. One panel has a UDI with human-readable and machine-readable parts. This provides a compact package with UDI compliance for regulated contact lenses. The wrap prevents accidental separation of the sealed package.

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21. Multilayer Pharmaceutical Packaging Film with Antistatic Properties and Potassium Ionomer-Infused Inner Layer

22. Multilayer Thermoplastic Packaging Film with Potassium Ionomer Antistatic Inner Layer

23. Blow-Fill-Seal Aseptic Packaging System with Continuous Sterilant Flow for Low-Acid Foods

24. Automated Pharmaceutical Packaging with Stepwise Compliance Verification and Error Detection

25. Laser Marking System with Authorization Verification and Smartphone-Based Quarantine Management for Packaging

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