Selenium Sulfide Stabilization in Plant-Based Shampoo Formulations
Selenium sulfide presents significant stabilization challenges when formulated with plant-based surfactants. In aqueous solutions, selenium sulfide particles exhibit a tendency to agglomerate, with particle sizes increasing from 20-200nm to larger clusters within 72 hours at pH values above 5.5. This instability manifests as phase separation, color shifts from orange-red to gray-brown, and diminished antifungal efficacy against Malassezia species on the scalp.
The fundamental challenge lies in maintaining selenium sulfide's antifungal potency while achieving dispersion stability in environmentally preferable surfactant systems that lack the strong ionic characteristics of conventional synthetic detergents.
This page brings together solutions from recent research—including chitosan quaternary ammonium salt encapsulation techniques, ultrasound-extracted plant surfactant systems, electrochemically synthesized high-purity nanoparticles, and specialized cationic polysaccharide stabilizers. These and other approaches enable formulators to develop stable, effective selenium sulfide products while meeting increasing consumer and regulatory demands for plant-derived ingredients.
1. Shampoo Composition with Ultrasound-Extracted Plant Ingredients and Surfactants
SHIHUANUO GUANGDONG BIOTECHNOLOGY CO LTD, 2024
Organic plant care anti-dandruff shampoo composition, preparation method, and use that addresses the environmental and irritation concerns associated with traditional anti-dandruff products. The composition comprises plant extracts of ginger root, Platycladus orientalis leaf, Polygonum multiflorum, sesame seed, and camellia seed, combined with surfactants like cocamidopropyl betaine and sodium lauryl sulfate. The plant extracts are extracted through ultrasound-assisted extraction and then combined with the surfactants to form a shampoo. The composition meets the 4.5-5.5 pH range for optimal scalp health, while its plant-derived ingredients offer natural antimicrobial and keratin-strengthening properties. The formulation is free of harsh chemicals and synthetic fragrances, making it suitable for sensitive skin and environmentally conscious consumers.
2. Encapsulation Method of Selenium Disulfide with Chitosan Quaternary Ammonium Salt
GUANGZHOU PANYU POLYTECHNIC, 2024
A method for encapsulating selenium disulfide with chitosan quaternary ammonium salt to create a stable, water-soluble, and effective anti-dandruff ingredient for shampoo formulations. The encapsulation process involves wrapping selenium disulfide with chitosan quaternary ammonium salt, which enhances the deposition of selenium disulfide on hair and scalp while reducing its solubility issues. The encapsulated selenium disulfide formulation provides enhanced anti-dandruff efficacy through synergistic action with chitosan quaternary ammonium salt, which forms a protective film on the hair surface during shampooing.
3. Shampoo Composition with Selenium Sulfide and Alkylphenol Ether Sulfosuccinate
Shi Baolan, 2024
Anti-dandruff shampoo composition containing selenium sulfide, alkylphenol ether sulfosuccinate, sodium dodecyl ether sulfate, polyquaternium-7, guar gum hydroxypropyl trimethyl ammonium chloride, citric acid, fragrance, conditioning agent, thickener, emulsifier, and pine extract. The composition provides effective anti-dandruff properties and improved scalp health compared to traditional selenium sulfide shampoos. The specific ingredient ratios and preparation method are described to achieve high purity selenium sulfide, optimal shampoo performance, and avoid contamination issues.
4. Selenium Disulfide Shampoo with Suspension-Stable Surfactant and Cationic Polysaccharide System
OPAL COSMETICS HUIZHOU CO LTD, 2023
A selenium-based anti-dandruff shampoo formulation that combines a suspension-stable selenium disulfide with a synergistic surfactant system. The formulation comprises a selenium disulfide component, a surfactant system comprising an anionic surfactant and a nonionic surfactant, and a cationic polysaccharide component. The surfactant system provides enhanced cleansing properties, while the cationic polysaccharide component enhances the shampoo's ability to penetrate the scalp and deliver the selenium disulfide effectively. The formulation demonstrates improved suspension stability and enhanced anti-dandruff efficacy compared to conventional selenium-based shampoos.
5. Underwear Soap Composition with Selenium Disulfide and Natural Extracts
DAYOU PHARMACEUTICAL YANGZHOU CO LTD, 2023
Antifungal underwear soap that combines the benefits of selenium disulfide for antifungal activity with the enhanced cleaning and skin protection properties of natural ingredients. The soap contains a synergistic blend of tea saponin, selenium disulfide, acaricide, antibacterial agents, menthol, lavender essence, tea polyphenols, stearic acid, propylene glycol, lauric acid, lard, coconut oil, Sophora flavescens extract, green tea extract, surfactant, and alkaline protease. This composition provides both antifungal protection and skin care benefits, with the selenium disulfide enhancing the antifungal properties while the natural ingredients deliver moisturizing and soothing effects.
6. Selenium Disulfide Composition with Integrated Surfactant and Moisturizing System
SHENZHEN XICHUAN SKIN MEDICAL TECH CO LTD, 2023
A synergistic selenium disulfide composition for anti-dandruff shampoo formulations that combines the potent antifungal properties of selenium disulfide with the surfactant and moisturizing capabilities of a surfactant system. The composition enhances the efficacy of selenium disulfide through controlled synergistic interactions with surfactants and moisturizers, particularly in anti-dandruff shampoos. The formulation maintains stability and performance characteristics of selenium disulfide while providing a balanced surfactant system.
7. Shampoo Formulation with Selenium Disulfide and Surfactant System for Enhanced Stability and Suspension Properties
WUXI ZHIYAN BIOLOGICAL TECH CO LTD, 2022
A selenium disulfide shampoo formulation that addresses common issues associated with selenium disulfide in shampoos. The formulation combines a selenium disulfide system with a surfactant system to create a stable and effective shampoo. The surfactant system enhances the suspension properties of the selenium disulfide, while the surfactant system also helps maintain the selenium disulfide's stability under various conditions. The formulation maintains a consistent suspension and maintains the selenium disulfide's color and efficacy.
8. Selenium Sulfide Shampoo Composition with Electrochemically Synthesized High-Purity Nano-Particles and Stabilizing Surfactant-Emulsifier System
LIANG XIAOLONG, 2022
A selenium sulfide shampoo composition that addresses dandruff through a novel combination of surfactants and anti-fungal agents. The composition comprises a selenium sulfide formulation with a nano-particle size of 20-200nm, which is stabilized by a combination of surfactants and emulsifiers. The selenium sulfide is prepared through an electrochemical process that produces a high-purity product with a purity greater than 99.99%. The formulation also includes additional ingredients such as surfactants, emulsifiers, and thickeners to enhance its performance. The selenium sulfide is specifically designed to provide effective anti-dandruff properties while maintaining its cleansing and moisturizing capabilities.
9. Shampoo Composition with High-Purity Selenium Sulfide and Ionization-Enhanced Surfactant System
LIANG XIAOLONG, 2022
A shampoo composition that provides effective anti-dandruff treatment while maintaining a non-sticky hair texture. The composition comprises a surfactant system with high-purity selenium sulfide as the primary active ingredient, along with specialized surfactants and thickeners. The selenium sulfide is formulated with a unique ionization mechanism that enhances its antifungal efficacy while maintaining its cleaning properties. The surfactant system is combined with polyquaternium-7, guar hydroxypropyl trimethyl ammonium chloride, and other ingredients to create a balanced formulation that addresses multiple aspects of dandruff management.
10. Selenium Disulfide Foaming Agent with Surfactant-Stabilized Ultrafine Particle Dispersion
NEW PRIMITIVE BEIJING MEDICAL SCIENCE AND TECH LIMITED CO, 2022
Selenium disulfide foaming agent for shampooing that addresses common issues with conventional selenium disulfide products. The agent combines a fine, ultrafine selenium disulfide powder with a surfactant system that stabilizes the selenium particles, enabling precise control over their dispersion and stability. The surfactant system also enhances penetration and distribution of the selenium disulfide, allowing it to deliver its therapeutic effects more effectively. The agent's unique surfactant composition prevents oxidation and discoloration, while maintaining the necessary penetration properties for effective treatment of scalp conditions.
11. Selenium Disulfide Lotion with Ultrafine Particle Size Distribution for Uniform Dispersion in Water-Based Emulsions
DAYOU PHARMACEUTICAL YANGZHOU CO LTD, 2022
A selenium disulfide lotion composition that provides stable and effective antifungal activity through a novel ultrafine particle formulation. The composition comprises selenium disulfide as the active ingredient, with a particle size distribution between 1.0 and 15.0 μm, and a water-based formulation containing up to 3% selenium disulfide. The ultrafine particles enable uniform dispersion in water-in-oil emulsions, ensuring consistent selenium disulfide concentrations and improved skin penetration.
12. Shampoo Composition with Selenium Sulfide-Loaded Carbon Spheres via Electrochemical and Gas-Phase Processes
XIAOQING ZHENG, 2021
Anti-dandruff and anti-itch shampoo composition containing selenium sulfide in a stable and effective form. The selenium sulfide is loaded onto carbon spheres prepared by hydrothermal synthesis. The carbon spheres provide a carrier for the selenium sulfide and improve its dispersion and stability in the shampoo. The selenium sulfide is also prepared by electrochemical reduction and gas-phase reaction. This allows controlled loading of selenium sulfide onto the carbon spheres. The resulting selenium sulfide composite powder is used in the shampoo composition along with other surfactants, preservatives, etc. The composition provides improved anti-dandruff and anti-itch efficacy compared to free selenium sulfide.
13. Selenium Sulfide Composite Powder with Nano-Sized Carbon Spheres for Uniform Distribution
XIAOQING ZHENG, 2021
A selenium sulfide composite powder for shampoo that provides enhanced anti-dandruff and scalp health benefits through a novel, water-soluble formulation. The powder is prepared by creating nano-sized carbon spheres through a process that incorporates selenium sulfide into the carbon matrix. The selenium sulfide is uniformly distributed on the surface of the carbon spheres, creating a stable, water-soluble product that can be easily incorporated into shampoos. This formulation addresses the traditional challenges of selenium sulfide delivery, including its high solubility and poor stability in water-based systems.
14. Shampoo Composition with Selenium Sulfide, Panthenol, Dichlorobenzyl Alcohol, Acorus Calamus Extract, Cnidium Monnieri Extract, and Polydimethylsiloxane
HUIZHOU JIYUAN BIOTECHNOLOGY CO LTD, 2021
Mild, low-irritating shampoo that effectively removes dandruff, relieves itching, and controls mites without harsh ingredients. The shampoo contains selenium sulfide for anti-dandruff and anti-mite properties, panthenol to moisturize and repair the scalp, dichlorobenzyl alcohol for antibacterial and anti-inflammatory benefits, Acorus calamus extract for antioxidant and metabolism improvement, Cnidium monnieri extract to regulate oil secretion, and Polydimethylsiloxane for cleansing and non-sticky feel. The formula avoids harsh surfactants and detergents to minimize scalp irritation.
15. Shampoo Soap with Selenium Disulfide and Camellia Seed Extract in Stable Heat-Formed Dispersion
WANG JIANGONG, 2021
Shampoo soap containing selenium disulfide plant extract that provides effective cleansing, moisturizing, and anti-dandruff properties. The soap contains selenium disulfide, a natural ingredient that inhibits sebaceous gland secretion, and camellia seed extract, which enhances skin barrier function. The selenium disulfide is dispersed in a stable, heat-formed system within the soap base, ensuring consistent performance and preventing irritation. The formulation achieves strong cleansing, moisturizing, and anti-dandruff benefits without the need for chemical preservatives or irritating surfactants.
16. Shampoo Formulation with EDTA, Dichlorobenzyl Alcohol, Phellinus Linteus, Cnidium Monnieri, Neem, and Selenium Sulfide
Huizhou Guangda Cosmetics Co., Ltd., 2021
Mild, stable, and effective anti-dandruff shampoo formulation that provides good scalp hydration, oil control, anti-dandruff, anti-inflammation, and anti-itch relief. The shampoo contains components like EDTA, dichlorobenzyl alcohol, Phellinus linteus extract, Cnidium monnieri seed extract, Neem extract, and Selenium sulfide. The formulation aims to load active ingredients onto the scalp for better deposition, absorption, and utilization. The shampoo also uses thickeners, conditioners, and humectants to maintain stability and moisturization.
17. Shampoo Formulation with Magnolia Bark, Sophora Flavescens, and Aloe Vera Extracts Incorporating Natural Surfactants and Humectants
GUANGZHOU AOTING BIOTECHNOLOGY CO LTD, 2020
A plant-based anti-dandruff shampoo that effectively combats scalp conditions while providing gentle cleansing and moisturizing properties. The formulation combines natural ingredients like Magnolia bark extract, Sophora flavescens root extract, and Aloe vera extract to address both dandruff and scalp issues. The unique blend of surfactants, humectants, and moisturizers creates a balanced cleansing and moisturizing effect, while the plant extracts provide anti-inflammatory and soothing properties. The formulation is free of harsh chemicals and synthetic fragrances, making it suitable for sensitive skin and scalp.
18. Shampoo Composition with Zanthoxylum Bungeanum Extract, Crocodile Oil, Pyridone Ethanolamine Salt, and Selenium Sulfide
MANZHEN IND GUANGZHOU CO LTD, 2020
An anti-dandruff shampoo that effectively treats dandruff, scalp itching, and inflammation without irritating the scalp. The shampoo contains ingredients like Zanthoxylum bungeanum extract, crocodile oil, pyridone ethanolamine salt, and selenium sulfide. The extract has antibacterial, antifungal, anti-inflammatory, and antipruritic properties to kill scalp fungi and prevent dandruff. Crocodile oil moisturizes and repairs the scalp, prevents dryness and itching. Pyridone ethanolamine salt and selenium sulfide are milder anti-dandruff agents. The shampoo also contains conditioners like allantoin and salicylic acid. The preparation method involves adding ingredients in specific order and controlling temperature to ensure sol
19. Shampoo Composition with Plant-Derived Additive and Surfactants for Keratinocyte Hyperplasia
GUANGDONG DANZI GROUP CO LTD, 2018
A shampoo composition and preparation method for reducing scalp irritation and dandruff, particularly for individuals with excessive keratinocyte hyperplasia. The composition contains a plant-derived de-shoulder additive that, when combined with surfactants and preservatives, effectively reduces scalp irritation and dandruff while maintaining gentle cleansing properties. The additive is derived from plant sources, is safe, and has no known irritation potential, making it suitable for sensitive scalp conditions.
20. Composition of Plant Extracts from Camellia Sinensis, Biota Orientalis, Ginseng, Ginger, and Angelica Sinensis
QIANCAOWANMU TECHNOLOGY CO LTD, 2016
Plant extract composition and its application in cosmetics, specifically shampoo. The composition contains extracts from Camellia sinensis, Biota orientalis, ginseng, ginger, and Angelica sinensis. The extracts are used in cosmetics, like shampoo, at a total weight of 1-50% as an active ingredient. The extracts reduce dandruff, oiliness, itching, promote hair growth, and prevent greying. The composition is mixed with other shampoo ingredients like surfactants, emollients, and preservatives to make the final product.
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