12 patents in this list

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The human scalp hosts a complex microbiome of over 100 bacterial and fungal species, with population densities reaching 106 organisms per square centimeter. This delicate ecosystem can be disrupted by traditional scalp treatments that contain harsh surfactants and antimicrobial agents, leading to chronic conditions like seborrheic dermatitis, folliculitis, and compromised barrier function.

The fundamental challenge lies in developing formulations that selectively modulate problematic microorganisms while preserving beneficial species and maintaining the scalp's natural defense mechanisms.

This page brings together solutions from recent research—including plant fermentation filtrates with prebiotic properties, microbiome-modulating compounds like dihydroberberine, and synergistic botanical extract combinations with alpha-glucan oligosaccharides. These and other approaches focus on restoring scalp homeostasis through targeted interventions that work with, rather than against, the native microbiome.

1. Composition of Plant Fermentation Filtrate with Natural Extracts for Scalp Microecology Regulation

GUANGDONG YOUSHANG COSMETICS CO LTD, 2024

A composition for regulating scalp microecology and preventing hair loss that combines plant fermentation filtrate with a natural anti-hair loss extract. The composition contains a blend of Centella asiatica, Edelweiss, and anti-hair loss extract, which creates a balanced ecosystem that prevents scalp infections while maintaining healthy hair growth. The fermentation process produces a rich source of prebiotic compounds that compete with pathogenic bacteria for resources, while the anti-hair loss extract provides targeted anti-hair loss effects. This composition is safe, mild, and non-irritating, with a unique synergistic effect that addresses both scalp health and hair loss.

2. Dihydroberberine Compound for Modulating Scalp Microbiota with Anti-Inflammatory Properties

NANJING NUTRABUILDING BIO TECH CO LTD, 2024

Dihydroberberine (DHB) is a natural compound that modulates the balance of scalp microbiota, specifically inhibiting the growth of microorganisms associated with hair follicle, scalp, and hair health. DHB has been shown to regulate the microbiome, reduce inflammation, and prevent conditions such as folliculitis, seborrheic dermatitis, and alopecia. The compound's anti-inflammatory properties make it a valuable therapeutic agent for scalp health, while its ability to modulate the microbiome offers a novel approach to treating scalp conditions.

3. Composition of Botanical Extracts with Hyaluronic Acid and Capryloylglycine for Scalp Ecological Balance

GUANGZHOU WEIWOMEI COMMODITY CO LTD, 2024

Composition and method for regulating scalp ecological balance to improve scalp health and reduce issues like oiliness, inflammation, and dandruff. The composition contains extracts from camellia seeds, ginger, sea buckthorn, Vitex japonica, and spruce. It is prepared by mixing the extracts and other ingredients like hyaluronic acid, butylene glycol, and capryloylglycine. The method involves combining the extracts first and then adding the other ingredients while stirring. The composition can be used in shampoo formulations to provide scalp benefits without irritation.

4. Composition with Plant Extracts, Lactobacillus Fermentation Products, and Prebiotics for Scalp Microbiome Balance

SHANGHAI BOTONG WEIDA BIOTECHNOLOGY DEV CO LTD, 2023

A composition for improving the microecological balance of the scalp environment to address scalp problems like dandruff, itchiness, and oiliness. The composition contains extracts from ginseng, ginger, Platycladus orientalis, and Platycladus arborvitae leaves, lactobacillus fermentation products, and skin prebiotics. These ingredients promote a healthy scalp microbiome, reduce inflammation, and restore scalp barrier function. The composition can be used in cosmetics like scalp care essences to address scalp issues without relying on antibiotics or harsh chemicals.

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5. Topical Scalp Formulation with Alpha-Glucan Oligosaccharides, Botanical Extracts, and Plant-Derived Compounds

NUTRACEUTICAL WELLNESS INC, 2023

Topical formulations for scalp health that target the microbiome and promote balance through a synergistic approach of alpha-glucan oligosaccharides, botanical extracts, and plant-derived compounds. These formulations contain a combination of alpha-glucan oligosaccharides, botanical extracts like kunzea pomifera, syzygium luehmannii, tasmannia lanceolata, and pisum sativum, along with plant-derived compounds like sarcosine, to create a balanced scalp microbiome. The formulation combines these ingredients to enhance scalp health through reduced sebum buildup, improved pH balance, and increased microbial diversity.

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6. Scalp Microbiota-Regulating Composition with Hydrolyzed Yeast Protein, Glucan Oligosaccharides, Inulin, Lactobacillus Ferment Filtrate, and Centella Asiatica Extract

FORMULA COSMETICS TECHNOLOGY CO LTD, 2023

Composition for regulating scalp microbiota to prevent dandruff and itching without relying on traditional antifungal agents. The composition contains ingredients like hydrolyzed yeast protein, glucan oligosaccharides, inulin, lactobacillus ferment filtrate, and centella asiatica extract. These ingredients synergistically balance scalp microbiota, improve barrier function, and reduce desquamation and inflammation to prevent dandruff and itching.

7. Composition for Keratin Material Treatment Containing Antioxidant Agent, Bifidobacterium Lysate, and Yeast Extract

OREAL, 2023

Cosmetic treatment of keratin materials, in particular human keratin materials such as the scalp and the hair, using a composition that reduces irritation and itching linked to the oxidation of sebum. The treatment includes at least 0.5% by weight of antioxidant agent, a lysate of Bifidobacterium species and a yeast extract.

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8. Scalp Microecological Stabilizer with Natural Ingredients for Microbiome Balance

DONGPING JIUXIN BIOCHEMISTRY CO LTD, 2023

A scalp microecological stabilizer for hair care products that maintains the natural balance of the scalp microbiome. The stabilizer, comprising a combination of natural ingredients like panthenol, coconut oil, and oat protein, prevents excessive microbial proliferation while preserving the scalp's natural barrier function. This formulation addresses the root causes of scalp issues like dandruff and itchiness by maintaining a healthy balance of microorganisms, rather than disrupting it.

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9. Shampoo Composition with Lactobacillus/Soybean Fermentation Filtrate, Chicory Extract, and Agave Leaf Extract Combined with Sarcosinate Surfactants

Guangzhou Nichu Cosmetics Co., Ltd., Tianjin Niqu Biotechnology Co., Ltd., TIANJIN NIQU BIOTECHNOLOGY CO LTD, 2022

A shampoo composition that maintains scalp microecological balance while providing effective dandruff, oil control, and itching relief. The composition combines lactobacillus/soybean milk fermentation product filtrate, chicory extract, and Taikui agave leaf extract with potassium lauroyl sarcosinate, lauroyl sarcosine triethanolamine salt, and sodium myristoyl sarcosinate. The formulation maintains the natural balance of the scalp microbiome while addressing dandruff, oil buildup, and itching.

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10. Scalp Care Composition with Tea and Ginseng Saponins, Propylene Glycol Laurate, Phytosphingosine, and Botanical Extracts

Guangzhou Degoo Personal Care Products Co., Ltd., GUANGZHOU DEGU PERSONAL-CARE SUPPLY CO LTD, 2021

Scalp care composition that improves scalp microecological diversity to address scalp issues like dandruff, itching, and sensitivity. The composition contains tea saponin, ginseng saponins, propylene glycol laurate, phytosphingosine, lactic acid, peppermint oil, menthol, allantoin, matrine extract, sodium benzoate, and potassium sorbate. The compounds work synergistically to regulate scalp microbes, sebum, and barrier function. The composition avoids excessive bacterial killing and overuse of preservatives.

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11. Composition of Natural Extracts with Ultra-High Pressure Homogenization for Hair and Scalp Care

BIO RACE BIOTECH HANGZHOU CO LTD, 2021

Hair and scalp care composition and preparation method using natural extracts and processing to prevent and treat dandruff and hair loss. The composition contains extracts from Morinda citrifolia, grape ferment, arugula, walnut, and hydrolyzed pea protein. The extracts are combined with glycerin, butylene glycol, poloxamer, hyaluronic acid, allantoin, citric acid, EDTA, colloidal silver, and water. The composition is prepared using ultra-high pressure homogenization to reduce particle size. The small particle size enables better absorption into the scalp and hair follicles for improved effectiveness.

12. Composition Comprising Fermentation Filtrates, Ginger Extract, and Oligofructose for Scalp Flora Balance and Barrier Structure Repair

JIANGSU WEIKANG BIOTECHNOLOGY CO LTD, 2020

Composition and method for improving scalp ecology and scalp care products containing the composition. The composition balances scalp flora, repairs barrier structure, and regulates hair follicle growth by using specific fermentation filtrates from beneficial bacteria strains, ginger extract, and oligofructose.

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