Anti-Glycation Agent Formulations for Skin Anti-Aging

A cosmetic composition and facial mask for anti-aging skin that targets protein non-enzymatic glycation reaction (NEG) through a dual-action approach. The composition incorporates natural products like Mullein glycosides, salvianolic acid B, and a second natural product, which together inhibit AGE formation and enhance antioxidant activity. The composition protects skin from UV damage while promoting cellular antioxidant defenses, resulting in improved skin elasticity and reduced wrinkle appearance.

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A dual-target repair and anti-aging composition that generates hyaluronic acid and reduces skin collagen loss through synergistic action of tetradecylaminobutyrylvalinamidobutyric acid (TBAV) and hydroxypropyl tetrahydropyrantriol. The composition combines TBAV, a potent activator of TGF-β receptors, with hydroxypropyl tetrahydropyrantriol, which improves glycosaminoglycan expression and skin barrier function. This dual-action approach enables sustained hyaluronic acid production while simultaneously repairing skin collagen and elastin. The composition is formulated as a gentle, non-irritating cosmetic product that promotes skin firmness, elasticity, and hydration while addressing skin aging and inflammation.

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Decursinol, a natural compound derived from the Angelica gigas plant, exhibits potent anti-glycation, skin pore reduction, and skin exfoliation effects. This compound, which has been isolated from Angelica gigas, demonstrates superior efficacy compared to conventional anti-glycation agents like aminoguanidine. Decursinol's anti-glycation activity is comparable to aminoguanidine, while its skin pore-reducing and exfoliating properties surpass those of commercial products. Its safety profile is also comparable to aminoguanidine, making it a promising candidate for anti-aging formulations.

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A natural anti-aging skin care composition containing extracts of Centella asiatica, ginseng root, Inonotus obliquus, Tremella fuciformis, magnolia flower, and burdock root in specific amounts for sustained and effective anti-aging effects. The composition can be prepared by extracting the plant materials and combining them in the specified proportions.

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A skin care composition containing Boseine and recombinant type III human collagen in specific weight ratios to target and enhance collagen production in the skin. The composition can be used in skin repair and anti-aging products. The Boseine to collagen weight ratio is 1:0.001 to 1:0.2, with Boseine at 0.5-1.2% concentration. It promotes expression of collagen genes to counter UV-induced collagen degradation and aging effects.

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Anti-aging composition that can repair skin injury, promote proliferation and differentiation of epidermal cells, remove oxygen free radicals, delay skin aging, promote regeneration of elastin, promote repair of elastic fibers, up-regulate antioxidant enzyme activity, play a good role in moisturizing, resisting oxidation, resists aging and removing wrinkles, and have wide application prospects. The composition includes 10-30% of hyaluronic acid, 0.1g of nipagin methyl ester, 0.5g of D-panthenol, 0.2g of oat B-glucan, 0.1g of HPS, 0.1g of perfume, 0.1g of MTI, 1g of centella asiatica extract, 0.1g of snake venom peptide, 80.1g of hexapeptide, 120.1g of decapeptide, 0.1g of oligopeptide-3 (Lumixyil), mi Shengtai, and purslane extract.

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A composition to inhibit skin glycation, the non-enzymatic reaction between sugars and proteins that causes skin aging and stiffness. The composition contains extracts like Phellodendron amurense bark, Schisandra fruit, and Notoginseng root, which have been shown to inhibit skin glycation, collagen glycation, intracellular glycation, advanced glycation product (AGE) generation, and AGE-induced inflammation. The composition can be used in pharmaceuticals, cosmetics, and foods to prevent skin glycation and aging.

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Topical composition containing ergothioneine, an analog, derivative, or salt thereof, for preventing or improving skin aging, particularly premature aging from UV exposure. Ergothioneine is an amino acid derivative found in fungi and some bacteria that is also produced by the human body. The composition can be applied to skin to alleviate signs of premature aging like wrinkles, improve elasticity, firmness, radiance, and texture, without causing irritation.

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An anti-aging cosmetic composition that improves skin health and appearance. The composition contains a combination of three ingredients: methylsilanol mannuronate, hydroxypropyl tetrahydropyran triol, and rhamnose. These ingredients work together to improve skin elasticity, reduce inflammation, and promote collagen production. The composition can be used in creams, lotions, and other cosmetic products.

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Skin care composition containing extract of Dianthus dianthus (ground dianthus) for anti-aging benefits. The composition helps prevent skin wrinkles, improve skin tone, reduce pore size, and inhibit skin glycation. The ground dianthus extract has antioxidant, anti-glycation, and anti-inflammatory properties. It can be used in lotions, creams, gels, and other skin care products.

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A composition and product system that effectively inhibits the formation of advanced glycosylation end-products (AGEs) in the skin, preventing wrinkles, firming, and brightening. The composition contains a synergistic blend of natural extracts, including Himemoin yeast extract, Pin jujube extract, spirulina extract, soybean alfalfa extract, carnosine, and Momordica grosvenori extract, which work together to modulate collagen and elastin degradation pathways. The composition is formulated with a balance of humectants, emollients, and skin conditioners, with a specific ratio of 8:8:10:0.03:0.4:5:5:5:5:0.03, and is combined with a solvent to achieve the desired formulation.

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A synergistic skin anti-aging composition that combines multiple bioactive ingredients to deliver comprehensive skin rejuvenation. The composition comprises a balanced blend of carbohydrate isomers, Sphingomonas fermentation product extract, ceramide, hydroxy pinacolone retinoate, phytosphingosine, and gentian root extract. This combination provides potent anti-aging benefits, including improved skin texture, reduced fine lines, enhanced hydration, and enhanced skin elasticity, while also addressing skin aging concerns through its ability to reduce water loss and improve skin brightness.

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Composition for improving skin conditions, particularly addressing skin aging, wrinkles, and skin elasticity, through inhibition of glycation and elastase activity. The composition comprises a compound that selectively inhibits glycation and elastase activity, thereby preventing the formation of advanced glycosylation end-products and elastase degradation products that contribute to skin aging and wrinkle formation.

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Composition for anti-glycation, anti-oxidation, anti-wrinkle, and moisturizing properties that contains seaweed extract from Irish moss, coral powder, and a peptide called acetyl hexapeptide-8. The composition improves skin health by inhibiting glycation, reducing oxidative stress, preventing wrinkles, and enhancing skin hydration. The combination of these three components provides superior benefits compared to using each ingredient individually.

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An anti-aging cosmetic composition that improves skin elasticity, reduces wrinkles, and evens skin tone. The composition contains collagen-promoting, signal-blocking, uniform skin color, cutin-regulating, and antioxidant components. The collagen-promoting component promotes collagen synthesis, the signal-blocking component relaxes muscles, the uniform skin color component evens skin tone, the cutin-regulating component regulates skin barrier function, and the antioxidant component protects against oxidative damage.

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Wasabi leaf extract inhibits skin aging and acne through mechanisms that prevent glycation, regulate inflammation, and modulate skin barrier function. The extract, derived from the Japanese wasabi plant, contains compounds that target key pathways involved in the formation of advanced glycosylation end-products (AGEs) and inflammatory responses, thereby slowing skin aging and reducing acne development.

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A dermocosmetic formulation that combines the benefits of antioxidants, immunomodulators, and cell growth regulators to combat photoaging. The formulation specifically targets collagen, elastin, and glycosaminoglycans (GAG) synthesis, as well as the activity of the superoxide dismutase enzyme (SOD) and cell proliferation. It achieves this through a combination of amino acids, botanical extracts, esters, and glycols that work synergistically to protect the skin from UV damage while promoting the production of these essential skin components.

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Composition and formulation for anti-aging skin care products that targets multiple pathways of skin aging, including free radical scavenging, collagen synthesis, and DNA repair. The composition combines natural extracts like ginseng and seaweed with resveratrol, vitamin C, and other antioxidants to enhance skin's natural barrier function and collagen production. The formulation is designed to penetrate the skin effectively, providing sustained anti-aging benefits through multiple mechanisms of action.

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A skin care composition that prevents and treats skin aging, wrinkles, and skin discoloration through the inhibition of glycation and cross-linking in the skin. The composition utilizes chickpea extract, specifically the stem and root extracts, which contain compounds that prevent the formation of advanced glycosylation end products (AGEs) and collagen cross-links. These compounds inhibit the activity of enzymes involved in glycation and collagen degradation, thereby maintaining skin elasticity and firmness. The composition can be formulated into a topical treatment that provides long-lasting anti-aging benefits for the face, scalp, and body.

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Anti-aging skin care composition containing extract of pheasant's rice (Luzula capitate) as an active ingredient. The pheasant's rice extract inhibits skin collagen glycation and advanced glycation end products (AGEs) formation. It also has antioxidant properties. The composition can prevent skin wrinkles, improve skin tone, reduce pore size, and provide anti-aging benefits. The pheasant's rice extract can be combined with other ingredients like glycerin, butylene glycol, propylene glycol, etc. to make lotions, gels, creams, etc. for external skin application.

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