Under-Eye Wrinkle Elimination Strategies for Aging Skin
11 patents in this list
Updated:
The skin around the eyes presents unique challenges for wrinkle treatment, with its thickness measuring only 0.5mm compared to 2mm elsewhere on the face. This delicate area experiences up to 10,000 micro-movements daily through blinking and expression, while lacking sufficient oil glands to maintain moisture barriers—leading to premature signs of aging and wrinkle formation.
The fundamental challenge lies in delivering active ingredients deep enough into the skin structure to promote cellular renewal while maintaining the delicate moisture balance of the periorbital region.
This page brings together solutions from recent research—including microneedle delivery systems for ceramides and hyaluronic acid, multilamellar vesicle encapsulation technologies, and synergistic formulations combining retinoids with polypeptides. These and other approaches focus on both immediate wrinkle reduction and long-term dermal matrix support while respecting the unique characteristics of periorbital skin.
1. Microneedle Patch with Multilamellar Vesicle-Encapsulated Ceramide, Hyaluronic Acid, and Hydrolyzed Collagen
KOSUMEDEI SEIYAKU KK, 2023
Microneedle patches for enhancing skin moisture and reducing wrinkles. The patches have microneedles containing ceramide, hyaluronic acid or derivatives, and hydrolyzed collagen. The ceramide is encapsulated in multilamellar vesicles. The microneedles have a height of 50-300um and density of 50-2000/cm2. The composition allows active ingredients like ceramide and hyaluronic acid to penetrate the skin barrier when applied through the microneedles, increasing skin moisture and reducing wrinkles. The hydrolyzed collagen promotes fibroblast proliferation.
2. Eye Cream Composition with Vitamin E Acetate, Sodium Pyrrolidone Carboxylate, and rhFGF8a
HUAQIAO UNIVERSITY, 2021
An anti-wrinkle eye cream composition with ingredients like vitamin E acetate, sodium pyrrolidone carboxylate, and rhFGF8a to reduce wrinkles around the eyes. The cream also contains olive oil, soybean oil, emulsifiers, and water. The composition aims to improve skin texture, delay aging, reduce cell oxygen consumption, and accelerate metabolism for anti-wrinkle benefits.
3. Eye Cream Composition with Polymer Fillers and Emollients for Surface Wrinkle Concealment
Green Xinyan Biotechnology Co., Ltd., LVXINYAN BIOTECHNOLOGY CO LTD, 2020
Instant wrinkle-removing eye cream that provides a visual reduction of wrinkles without removing them from the root cause. The cream contains specific ingredients like polymer fillers, emollients, skin conditioners, and emulsifiers that fill fine lines, smooth the skin, and improve texture to give an instant wrinkle-reducing effect. The cream also avoids issues like pore clogging and slivering by using refreshing oils and solid esters for moisturization. The cream's components include polyglyceryl stearates, polyglyceryl distearates, sodium stearoyl lactylate, myristyl myristate, caryophyllin, green flower extract, panthenol, centella asiatica extract, trehalose, and acrylic polymers.
4. Vitamin E Eye Cream Composition with Condensed Resveratrol-Malate and Enhanced Transdermal Penetration Agents
GUANGZHOU ZHIMEI DAILY CHEMICAL TECH CO LTD, 2020
Vitamin E eye cream composition for anti-aging and dark circle reduction that is mild, non-irritating, and hypoallergenic for delicate eye skin. The composition condenses resveratrol and malic acid to improve water solubility and absorption. It also contains acid penetrants to help ingredients like vitamin E, anti-wrinkle activators, and volatile oil extracts pass through the skin's appendages for better transdermal absorption. The cream contains 8-12% of the condensed resveratrol-malate composition along with moisturizing ingredients like glycerin, hyaluronic acid, lecithin, and squalane.
5. Eye Cream Formulation with Retinoids, Composite Polypeptides, White Birch Extract, Steroids, and Polysaccharides
SHANGHAI LONGXI INVEST CO LTD, 2019
Anti-wrinkle eye cream formulation containing retinoids, composite polypeptides, white birch extract, steroids, solvents, antioxidants, polysaccharides, and humectants. The composition aims to improve anti-wrinkle, anti-aging, eliminate dark circles, and alleviate eye fatigue. The retinoids, polypeptides, and steroids work synergistically to enhance anti-wrinkle and anti-aging effects. The white birch extract improves collagen connectivity. The antioxidants protect eye cells. The polysaccharides and humectants moisturize the eye area. The solvents disperse the active ingredients.
6. Composition Comprising Fucoidan, Sodium Hyaluronate, and Witch Hazel Extract with Additional Components
RONG DING, 2019
Composition for reducing dark circles, bags under the eyes, and wrinkles under the eyes in skincare products. The composition contains biocarbohydrate-1 (fucoidan), sodium hyaluronate, North American witch hazel extract, allantoin, hesperidin methyl chalcone, chelating agent, tartaric acid, 1,2-hexanediol, preservatives, sodium polyacrylate, and glycerin. The composition provides benefits like moisturizing, soothing, anti-inflammatory, anti-aging, and antioxidant effects to diminish dark circles, bags, and wrinkles around the eyes.
7. Eye Skin Care Composition with Recombinant Hydrolysin and Hyaluronic Acid in Specified Mass Ratios
SHANDONG HUAXIHAIYU BIOLOGICAL MEDICINE CO LTD, 2019
Eye skin care composition containing recombinant hydrolysin (limpet protein) and hyaluronic acid to improve eye skin issues like dark circles, edema, bags, fine lines, dry lines, and fat particles. The composition has a mass ratio of hydrolysin to hyaluronic acid of 5:1 to 20:1, with preferred ratios of 15:1 to 10:1. The combination of hydrolysin and hyaluronic acid synergistically improves eye microcirculation to address eye skin problems.
8. Cosmetic Composition with Sodium Hyaluronate, Peptides, and Botanical Extracts
BEIJING SUNSHINE XUSHENG FINE CHEMICAL TECHNOLOGY RESEARCH INSTITUTE, 2018
Natural anti-wrinkle wrinkle composition for cosmetics that helps reduce wrinkles and signs of aging around the eyes. The composition contains ingredients like sodium hyaluronate, palm Acyl tripeptide-1, bio-sugar gum-1, purslane extract, hydrolyzed oat protein, mulberry root extract, red myrrh alcohol, ginger root extract, and vitamin E. The eye cream version adds additional ingredients like bisabolol, shea butter, and isodecyl pivalate. These ingredients work together to improve skin elasticity and reduce wrinkles without harsh chemicals or animal-derived products.
9. Eye Cream Composition with Hydrogenated Lecithin, Vitamin E, and Botanical Extracts
GUANGZHOU MISSJOY BIOTECHNOLOGY CO LTD, 2017
A nourishing anti-wrinkle eye cream that moisturizes, tightens, reduces wrinkles, increases fullness, and has anti-aging benefits. The cream contains ingredients like hydrogenated lecithin, vitamin E, safflower maple bark extract, baobab tree extract, sodium hyaluronate, white rose eggplant extract, and a lock water magnet to provide multiple skin benefits for the delicate eye area. The cream also contains oils, emollients, emulsifiers, thickeners, preservatives, fragrances, and other components to create a nourishing eye cream formula.
10. Composition of Lotus and Guava Leaf Extracts with Hyaluronic Acid and Ceramides for Eye Wrinkle Treatment
MA NANXING, 2016
A quick bounce eye wrinkles delay composition and preparation method for reducing eye wrinkles associated with aging. The composition contains ingredients like lotus extract, guava leaf extract, hyaluronic acid, ceramides, shea butter, jojoba oil, aloe vera gel, vitamin E, trehalose, lactoglobulin, gold powder, silica fume, glycerin, sorbitol, xanthan gum, PEG-60, and water. The composition ratio is adjusted for different versions with varying amounts of some ingredients. The composition is applied around the eyes to reduce wrinkles and aging signs.
11. Cosmetic Composition with Cyclomethicone, Raspberry Seed Oil, Dipalmitoyl Hydroxyproline, Chamomile Extract, Vitamins E and C, and Emollients
DORF PAULA, 2007
Cosmetic composition for reducing the appearance of facial lines and wrinkles, particularly around the eyes. The composition contains ingredients like cyclomethicone, raspberry seed oil, dipalmitoyl hydroxyproline, chamomile extract, vitamins E and C, and emollients to soften, nourish, moisturize, and simulate collagen contraction around the eyes. It also contains preservatives and antioxidants to stabilize the composition.
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