Elastin Enhancement Compounds for Skin Elasticity Improvement

Using demethoxypodopterin, a natural compound found in plants, to promote elastin production in skin. Elastin is a key protein for skin elasticity and reducing wrinkles. By discovering that demethoxypodopterin increases elastin generation by fibroblasts, the invention provides a way to improve skin firmness and resist sagging using this compound. It suggests using demethoxypodopterin as an ingredient in skin care products, medicines, and health foods to help maintain skin elasticity and combat aging.

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Multi-effect anti-aging skin care composition and preparation method using a specific combination of ingredients. The composition includes teprenone, collagen, hydroxypropyl tetrahydropyrantriol, and diamond micropowder. This blend of ingredients provides multiple anti-aging benefits like improving skin elasticity, reducing water loss, and boosting collagen production. The composition can be used in skin care products like creams and lotions.

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Enhancing biosynthesis of collagen and elastin, which are components of dermal tissue, and are enhanced when certain amino acids and oligopeptides are properly transported and administered topically or orally. The biosynthesis includes glycine, L-proline and divalent metal ions, each having a content ratio of 1:0.9 to 1:1.1, and a variety of oligopeptides in a single component for the biosynthesis of elastin and collagen.

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Anti-aging skin care product containing modified disaccharide polysulfates, elastin, collagen, and chondroitin sulfate to improve skin elasticity and firmness. The disaccharide polysulfate is obtained by sulfating a disaccharide. The anti-aging composition contains modified disaccharide polysulfate at 0.01-0.5% of the total product mass, collagen at 0.01-5%, and elastin at 0.01-5%. The composition promotes skin firmness, reduces wrinkles, and repairs the skin barrier.

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Vermilion chinensis extract improves skin condition through enhanced collagen and elastin production, particularly in the skin's dermal layer. The extract, with its anti-hyaluronidase activity, anti-inflammatory properties, and antioxidant capabilities, promotes skin elasticity and reduces wrinkle formation. By inhibiting collagen degradation and modulating inflammatory responses, the extract effectively increases skin moisture content, suppresses skin sensitivity, and improves skin tone.

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Steroid antibiotic that suppresses the expression of MMP-1 increased by ultraviolet rays and increases the expression of collagen and elastin. The antibiotic inhibits the expression of MMP-1 increased by ultraviolet rays and increases the expression of collagen and elastin.

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A dermal elasticity improving agent that promotes the production of LTBP2 and/or fibrillin 1, thereby increasing and/or stabilizing the dermal papillary layer fibers. The agent contains 1-(2-hydroxyethyl)-2-imidazolidinone or its derivatives as an active ingredient. These compounds enhance the expression of LTBP2 and/or fibrillin 1 in fibroblasts, leading to increased dermal papillary fiber growth and stabilization. This agent can be used in non-therapeutic cosmetic formulations to improve skin elasticity and wrinkle appearance.

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Using vitexin, a natural compound found in plants like chamomile and hops, to promote collagen and elastin production in the skin. Vitexin can be added to skin care products to help improve skin sagging, wrinkles, and loss of elasticity. The effect of vitexin on collagen and elastin production by human fibroblast cells was discovered. The concentration range for vitexin in skin products is 0.001-20% by weight.

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Tetrapeptide derivatives for skin repair and firming that enhance fibroblast activity, promote cell proliferation, and improve skin elasticity. The derivatives, with the sequence NA-Pro-Lys-Glu-Lys-OH, are designed to stimulate collagen production and skin firmness while maintaining non-irritating safety. They can be incorporated into topical formulations for skin rejuvenation, addressing the underlying causes of aging and environmental damage.

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A novel anti-aging firming composition that combines natural peptides, plant extracts, and a proprietary blend of peptides with specific skin cell functions to improve skin elasticity and firmness. The composition contains a unique combination of peptides, including Alpinia japonicus extract, muscle factor, and specific growth factors, which work synergistically to enhance collagen production, regulate elastin levels, and suppress excessive fibroblast activity. The composition is formulated in a water-based delivery system and is suitable for sensitive skin types.

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Pharmaceutical compositions that enhance elastin production in damaged tissues, particularly in skin and vascular tissues, through the combination of vitamin D and tannic acid. The compositions contain a vitamin D compound and a tannic acid compound, with concentrations ranging from 0.1 nM to 100 nM. This dual-action approach promotes elastin synthesis while counteracting the inhibitory effects of vitamin D and other elastin-degrading agents. The compositions can be administered orally or topically to improve tissue health and prevent age-related tissue damage.

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A composition containing a fermented extract of a mixed natural product blend for improving skin condition, reducing inflammation, and enhancing elasticity. The composition comprises a complex fermented extract obtained by fermenting a mixed extract of green tea, ginger, and cypress using lactic acid bacteria. The fermented extract has significantly higher anti-inflammatory and elastase inhibitory activity compared to the non-fermented extracts. This makes it useful for anti-inflammatory, skin elasticity enhancement, and wrinkle improvement applications.

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Composition for improving skin elasticity and wrinkles through enhanced basement membrane integrity. The composition incorporates a synergistic combination of cordycepin, andrographolide, and quercetin, which together strengthen the dermal layer and improve skin elasticity. This combination provides superior anti-aging effects compared to individual components alone, particularly when used together.

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A cosmetic composition that prevents skin aging by inhibiting elastase degradation of skin elastic fibers. The composition utilizes essential oil from silver fir branches, which contains limonene as its main component, with secondary components of alpha-pinene, camphene, and bornyl acetate in a specific molar ratio. The oil is combined with other anti-aging actives, including esters of acids and monoalcohols, to create a topical treatment that effectively prevents the breakdown of skin elastic fibers and maintains skin elasticity and suppleness.

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Antiaging and skin regeneration properties in pharmaceutical and cosmetic applications. The extract improves skin density, improves skin elasticity and firmness, maintains the collagen and elastin structure, avoiding its degradation.

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A composition containing elastin peptides and Sophora japonica extract that rapidly restores skin elasticity and hydration through enhanced elastin production. The composition combines elastin peptides with Sophora japonica extract, which contains bioactive compounds like rutin and papain, to promote skin tissue regeneration and improve skin elasticity. The combination of these two natural ingredients enables accelerated skin rejuvenation compared to traditional anti-aging treatments.

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A composition and method for promoting elastin production in human skin and materials through natural extracts, particularly from the four-leaf clover. The composition contains an extract of four-leaf clover, which is a natural source of elastin-promoting activity. The extract can be used in various cosmetic formulations, including creams, serums, and topical treatments, to enhance skin elasticity and firmness. The composition can also be administered orally to promote elastin production through systemic delivery.

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Composition for promoting elastin and collagen biosynthesis in fibroblasts, comprising glycine, L-proline, and divalent metal ions, with a specific ratio of glycine to L-proline of 1:0.9-1.1. The composition enhances fibroblast expression of genes involved in collagen and elastin biosynthesis, particularly through the synergistic action of glycine, L-proline, and divalent metal ions. This composition can be used to promote tissue repair and prevent skin aging and photoaging by supporting the production of elastin and collagen.

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A topical cosmetic composition that improves skin firmness and elasticity through a synergistic combination of plant extracts. The composition combines Argania spinosa kernel extract, dill extract, Myrciaria dubia fruit extract, Croton lechleri extract, and Morus alba fruit extract to enhance skin texture and structure. The extracts work together to increase elastin, collagen, laminin, and fibronectin production, leading to improved skin firmness, elasticity, and facial contouring. The composition can be formulated into a variety of topical products, including masks, serums, creams, and gels, and is suitable for use on the neck and facial areas.

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A composition and preparation method for anti-aging and wrinkle-reducing cosmetics that combines antioxidant properties with elastin supplementation. The composition comprises a synergistic blend of wine dregs extract, yeast fermentation products, Rehmannia glutinosa extract, kapok extract, glucan, Schizophyllan, and soy isoflavones. The formulation is formulated as a cosmetic product that provides comprehensive anti-aging and wrinkle repair capabilities through its antioxidant activity, elastin replenishment, and cell metabolism regulation.

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A composition for anti-wrinkle moisturizing and improving skin elasticity that contains specific ingredients like collagen peptides, elastin peptides, hyaluronic acid, salmon nasal cartilage powder, pomegranate extract, olive fruit extract, grape seed extract, and German chamomile flower extract. The composition aims to address skin aging concerns like wrinkles, dryness, roughness, and laxity. It can be used as a health care product for anti-wrinkle and moisturizing effects, and the composition can be prepared by mixing the components in specific ratios. The composition also contains adjuvants like D-sodium erythorbate, citric acid, pectin, xanthan gum, and sweeteners.

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A skincare product that utilizes a specific extract from the Putia flower (Protea cynaroides) to enhance skin cell function and barrier integrity. The extract, obtained through solvent extraction, contains compounds that specifically stimulate elastin production and mitochondrial activity in skin cells, thereby improving skin elasticity and reducing the visible signs of aging. The product can be used in a variety of formulations, including skincare creams, serums, and moisturizers, and is particularly beneficial for maintaining healthy skin barrier function and preventing premature aging.

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A cosmetic composition containing extracts from rosemary, grape fern, mulberry, and Porphyridium cruentum algae to moisturize, condition, and improve skin. The extracts increase skin antioxidant capacity, collagen, elastin, and laminin expression while inhibiting matrix metalloproteinases, inflammatory cytokines, and elastase. This reduces fine lines, wrinkles, sagging, inflammation, and improves skin firmness, radiance, and tone.

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A cosmetic composition for improving skin elasticity and wrinkles that utilizes a novel synergistic combination of natural ingredients. The composition incorporates a specific extract from the Syringa plant, which has been shown to possess unique properties that complement the skin's natural barrier function. The extract, when combined with other skin-protective agents, provides enhanced collagen synthesis, improved skin elasticity, and reduced wrinkle formation. The composition is formulated in various delivery systems, including liquid, gel, and ointment formats, to provide targeted benefits for the skin's surface.

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Peptide derivatives for skin repair and firmness, comprising a peptide with the amino acid sequence H-Ala-Hyp-Arg-Arg-NH-benzyl, which has been shown to promote fibroblast activity, keratinocyte proliferation, and collagen synthesis. The peptide is formulated into a cosmetic or pharmaceutical composition that can be used to enhance skin elasticity, firmness, and barrier function.

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Skin cosmetic with ingredients that alleviate wrinkles, improve skin firmness, and moisturize the skin. The cosmetic contains hydrolyzed elastin with a molecular weight of 30,000 or less, cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol, and optionally retinol or derivatives, ascorbic acid or derivatives, tocopherol or derivatives, tranexamic acid or derivatives, biwa extract, yoquinin extract, yuzu extract, shakyaku extract, royal jelly extract. The hydrolyzed elastin penetrates the skin better than intact elastin to improve wrinkles. The other ingredients enhance the anti-wrinkle effect.

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Composition for enhancing collagen and elastin biosynthesis in connective tissue, particularly through the synergistic action of glycine, L-proline, and divalent metal ions. The composition specifically targets fibroblasts and promotes the expression of genes involved in collagen and elastin biosynthesis, while also supporting the production of these proteins. The composition is formulated as a pharmaceutical or cosmetic ingredient, with a specific ratio of glycine: L-proline that optimizes the biosynthetic response.

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Compounds that modulate microRNAs regulating collagen, elastin, and fibrillin expression in skin cells to improve skin health and appearance. The compounds target miR-29a and miR-29b, which are known to inhibit collagen and elastin production in skin by binding to complementary sequences on target messenger RNA transcripts. By suppressing these microRNAs, the compounds enhance collagen, elastin, and fibrillin production, leading to improved skin elasticity, texture, and appearance.

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A cosmetic product that utilizes a small plant-derived compound, 16-Pakistan-24-acetyl alismanol A, to enhance skin elasticity and repair capabilities. The compound, with a molecular weight of 163.8, is derived from a natural source and has been shown to promote dermal cell proliferation, improve skin renewal, and increase elastin content in dermal fibroblasts. This leads to enhanced skin elasticity and improved skin repair mechanisms. The cosmetic product, comprising 16-Pakistan-24-acetyl alismanol A, is formulated into a facial cleanser that addresses the underlying causes of skin aging, including reduced cell proliferation, decreased elastin content, and impaired skin repair.

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A composition that enhances skin firmness and elasticity through the synergistic effects of multiple natural extracts. The composition combines extracts from Himanthalia elongata, Undaria pinnatifida, Saussurea involucrata, Morus alba fruit, Citrus aurantium dulcis (orange) callus culture extract, and Argania spinosa kernel extract. The extracts are combined in a specific ratio to promote procollagen-1 expression, increase lysyl oxidase activity, inhibit melanogenesis, and enhance elastin production, resulting in improved skin texture and firmness.

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A skin external preparation composition for enhancing skin volume, promoting skin regeneration, and improving skin elasticity through the use of buttercup extract as an active ingredient. The composition comprises buttercup extract, which is derived from Ranunculus japonicus Thunb, a perennial herb with medicinal properties, and is used to promote the proliferation and differentiation of human adipose-derived stem cells. The buttercup extract inhibits matrix metalloproteinase activity, a key factor in skin degradation, while enhancing skin regeneration and elasticity. The composition demonstrates significant benefits in promoting skin volume, regeneration, and elasticity, particularly in reducing wrinkles and improving skin texture.

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A skin care water containing fish seed extract and elastin that provides anti-aging benefits through a synergistic combination of elastin, fish seed extract, and oat β-glucan. The water balances skin moisture, promotes skin elasticity, and protects against environmental stressors. The composition includes a fish seed extract, oat β-glucan, sodium hyaluronate, and a blend of green tea extract, ascorbic acid, and plantain extract. This formulation offers a natural, non-chemical approach to addressing skin concerns while maintaining skin health.

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A cosmetic agent that enhances elastin synthesis in dermal fibroblasts to improve skin elasticity. The agent, containing GABA as an active ingredient, promotes the production of elastin, collagen, fibrillin-1, and fibrillin-2, thereby enhancing skin elasticity and preventing age-related skin degradation. The agent can be administered orally or topically, and its composition can be used in various cosmetic formulations, including lotions, creams, sprays, and patches.

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Peptide compounds that enhance skin and appendage health through targeted collagen and matrix synthesis. The compounds, comprising amino acids linked by peptidic bonds, specifically target lysine residues in collagen and elastin, and their derivatives. These compounds exhibit enhanced activity compared to unmodified peptides, particularly in stimulating collagen I and IV, elastin, fibronectin, laminin, and hyaluronic acid synthesis. They can be used individually or in combination to improve skin firmness, density, elasticity, and radiance, as well as treat signs of aging and imperfections.

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A composition for improving skin elasticity, pore contraction, antibacterial activity, acne suppression, sebum control, skin barrier improvement, skin immunity normalization, anti-inflammation, trouble improvement, skin moisturizing, and skin texture improvement. The composition comprises pine bark extract, ascorbic acid, vitamin E, and gamma linolenic acid complex in a specific ratio. This combination provides potent antioxidant and anti-inflammatory effects, as well as enhanced skin barrier function and immune system normalization, while exhibiting excellent skin penetration properties.

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Cosmetic composition that inhibits MMP-1 production, promotes collagen synthesis, and inhibits melanin production, with skin wrinkle improvement, skin whitening effect, skin elasticity improvement effect, skin barrier strengthening effect, antioxidant effect, and skin moisturizing effect.

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Anti-aging agent containing an arctigenin derivative that provides whitening, skin elasticity recovery, anti-inflammatory, and anti-aging effects. The agent contains an arctigenin derivative with a molecular formula of (C7-15 alkyl, C6-14 alkylcarbonyl, or hydroxyalkyl), which is a stable and potent anti-inflammatory agent with skin-protective properties. The agent's anti-aging effects include skin elasticity recovery, anti-wrinkle, anti-inflammatory, and melanin suppression, making it suitable for topical use in anti-aging products.

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A cosmetic product formulation that combines plant-derived active stretch factor AEF with mucin and white fungus polysaccharides to enhance skin elasticity. The formulation specifically incorporates yam root extract mucin, emblica extract, and tremella polysaccharides, which together provide superior moisturizing, anti-aging, and skin firming properties. The mucin and polysaccharides work synergistically to protect skin cells from extracellular substances while maintaining water-holding capacity, while the emblica extract enhances skin elasticity through its antioxidant and protein-modifying properties. The tremella polysaccharides further contribute to skin hydration and firmness. This formulation addresses the skin's natural barrier function and elastin/collagen degradation pathways, providing enhanced skin elasticity and reduced wrinkles.

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Desthiobiotin, a derivative of biotin, and its isomers, enhances elastin production and activity in the skin, particularly in reducing fine lines and wrinkles associated with skin aging. The compound promotes LOXL1 enzyme activity, which is essential for elastin remodeling, and has been shown to improve skin elasticity, texture, and moisturization. The composition can be applied directly to the skin and is particularly effective for treating signs of skin aging, including sagging, fine lines, and open pores.

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