5 patents in this list

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Seborrheic dermatitis affects up to 5% of the population, triggering inflammatory responses that lead to scaling, redness, and persistent itching. Clinical studies show that affected areas exhibit elevated levels of inflammatory cytokines, altered microbiome composition, and compromised skin barrier function, with symptoms often cycling between remission and flare-ups.

The challenge lies in developing formulations that can simultaneously address multiple pathogenic factors—inflammation, microbial imbalance, and barrier dysfunction—while maintaining long-term scalp health.

This page brings together solutions from recent research—including novel applications of fermentation filtrates, terpenoid-based CBR activators, botanical extract blends, and microbiome-regulating compounds. These and other approaches focus on creating gentle yet effective treatments that can prevent symptom recurrence while supporting the scalp's natural protective mechanisms.

1. Scalp Care Composition with Salmonella Sinensis Seed Extract for Inflammatory Cytokine Suppression

IKEDA BUSSAN CO LTD, 2024

Scalp care product that improves itch and dandruff by using an extract from the seeds of Salmonella sinensis. The extract suppresses inflammatory cytokine production to normalize the scalp environment and prevent dandruff and itching. The product can be used as a hair care or skin care product. The extract can be contained in an amount of 0.01-95% by mass.

2. Hair Product Composition with Green Pepper, White Willow Bark, Artemisia Annua, Cranberry, Jujube Bark, and Gentian Extracts

GUANGZHOU GOTDYA FINE CHEMICAL ENGINEERING CO LTD, 2023

Anti-dandruff and antipruritic composition for hair products like shampoo that contains extracts of green pepper, white willow bark, Artemisia annua, cranberry, jujube bark, and gentian. The composition aims to alleviate scalp sensitivity and discomfort, reduce dandruff, and soothe itching. The extracts have benefits like anti-inflammation, antioxidants, and antimicrobials. The composition can be added to hair products like shampoo at 2-10% by mass.

3. Scalp Microecology Regulating Composition with Lactobacillus/Soy Milk Fermentation Filtrate, Chicory Extract, and Agave Leaf Extract

TIANJIN NIQU BIOTECHNOLOGY CO LTD, 2020

Composition for regulating scalp microecology to improve dandruff, oil control, and itchiness. The composition contains lactobacillus/soy milk fermentation filtrate, chicory extract, and agave leaf extract. It also has surfactants, thickeners, pH regulators, conditioning agents, chelating agents, and anti-dandruff agents.

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4. Hair and Scalp Care Compositions with Terpenoid-Based CBR Activators

UNILEVER NV, 2010

Hair and scalp care compositions containing selected terpenoid compounds that can be used to treat and prevent inflammatory skin conditions like dandruff by rapidly reducing scalp itch. The terpenoids act as chemical signals called CBR activators that improve skin barrier function and reduce inflammation. Examples of effective terpenoids include 16-hydroxysumatrol, isophasellin, and silandrin. The compositions can be shampoos, conditioners, oils, or lotions applied to the hair and scalp. The terpenoids are added along with other hair care ingredients to provide dandruff relief.

5. Scalp Treatment Liquid with Acidic pH and Riboflavin for Indicating Application

WEI ZHANG, 1996

A liquid to fix itching and prevent dandruff by balancing skin pH. The liquid contains acid, citric acid, lactic acid, and riboflavin. It is applied to the scalp to relieve itching caused by seborrheic dermatitis and dandruff. The acidic pH helps maintain a healthy scalp environment and prevents fungal growth. The riboflavin provides a yellow color to indicate proper application. The liquid can be used as a scalp treatment instead of harsh chemicals.

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