Peptide Nanoliposome Development for Hair Follicle

A liposomal formulation of blue copper peptide for hair growth enhancement. The formulation combines blue copper peptide encapsulated in liposomes with Platycladus orientalis extract, which enhances hair growth by promoting angiogenesis, reducing scalp Propionibacterium acnes and Malassezia, and regulating scalp oil secretion. The liposomes facilitate transdermal delivery of the extract components into the hair follicle, where they stimulate hair growth while inhibiting excessive oil production.

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Nanoliposome for hair loss prevention and strengthening that contains a blend of ingredients like diaminopyrimidine oxide, plant extracts, lecithin, emulsifiers, antioxidants, and cholesterol. The liposome has anti-hair loss and hair solidifying properties due to the synergistic effects of the ingredients. The plant extracts like Platycladus orientalis, Radix Dipsaci, Radix Ophiopogonis, Rhodiola rosea, Laminaria japonica, Artemisia capillaris, Goldenseal fruit, and green tea improve scalp health, reduce inflammation, inhibit fungal growth, enhance blood circulation, and nourish hair follicles to prevent hair loss and promote hair growth.

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Engineered nanovesicles derived from human induced pluripotent stem cells (hiPSCs) that promote hair regeneration through targeted delivery of small interfering RNA (siRNA) against specific hair growth regulatory genes. The nanovesicles, encapsulated in uniform vesicles, contain siRNA targeting TGF-β1, Lats1, and SFRP1, which inhibit key pathways involved in hair follicle growth and maintenance. These nanovesicles can be engineered to target specific hair growth stages and are administered via microneedle injection to promote hair growth in conditions like androgenetic alopecia.

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A system for delivering black galangal extract and Gotu Kola extract in the form of nanoscale particles that combine the advantages of liposomes and niosomes. The particles are engineered to retain these bioactive compounds while maintaining their structural integrity. The system enables controlled release of these extracts through cell culture systems, providing a stable and sustained delivery of bioactive compounds for various applications, including wound healing, skin care, and hair growth promotion.

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A nano-composite for preventing hair loss, promoting hair growth, and fixing black hair through synergistic action of hair growth promoters, hair-fixing peptides, and black hair peptides. The nano-composite is a combination of diaminopyridine oxide, pyrrolidinyl diaminopyridine oxide, hair-growth peptides, hair-fixing peptides, and black hair peptides, which form a lipid bilayer structure that penetrates the skin's stratum corneum, interacts with keratin, and promotes active substance penetration into the hair follicle. The nano-composite provides enhanced anti-hair loss, anti-hair growth, and anti-black hair effects compared to conventional treatments, with a low content of active ingredients.

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Hair follicle stem cell regeneration peptide nanocapsules for promoting hair growth through targeted delivery of active peptides. The nanocapsules contain a peptide complex derived from hair follicle stem cells, encapsulated in a lipid matrix that enables precise penetration through the skin barrier. The peptide complex is purified from human hair follicle stem cells and processed into nano-lipid vesicles using a proprietary method. These nanocapsules deliver the active peptide to the hair follicle, where they stimulate hair growth through self-renewal and differentiation mechanisms.

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A composite polypeptide nanovesicle formulation for hair growth and prevention of hair loss, comprising a synergistic blend of hair growth-promoting peptides, anti-inflammatory peptides, and anti-androgenic peptides encapsulated in a biocompatible nanocarrier. The formulation combines multiple anti-hair loss mechanisms into a single delivery system, achieving enhanced efficacy through controlled release and penetration into the hair follicle. The nanovesicles have been demonstrated to significantly improve hair growth and prevent hair loss through their synergistic anti-hair loss mechanisms.

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Hair loss prevention and hair growth composition containing cholangio-3,5-diene, hair growth agents, antiandrogens, biologically active peptides, white birch extract, dextran, butylene glycol, and water. The composition improves hair growth, reduces hair loss, and enhances scalp health. The active ingredients work synergistically to promote hair follicle growth, repair, and anchoring, moisturize the scalp, and inhibit hair loss factors like DHT. The composition can be applied to hair products like oil, conditioner, lotion, shampoo, mask, etc.

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A topical hair growth agent containing a hair stromal cell activator that combines potassium channel opener activity with biologically active peptides to stimulate hair follicle activity and promote hair growth. The agent balances the potassium channel opener with biologically active peptides to enhance hair growth while minimizing irritation. The formulation can be applied to various hair care products including shampoos, conditioners, and hair growth treatments.

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An active peptide for hair growth that enhances keratin expression through targeted delivery. The peptide composition includes biotin tripeptide-1, myristoyl pentapeptide-17, myristoyl hexapeptide-16, tripeptide-1 copper, and acetyl tetrapeptide-3, with a concentration range of 0.0001-5%. These peptides, when encapsulated in a nano-inclusion system, exhibit superior stability, safety, and transdermal absorption compared to conventional peptides. The peptide formulation enables controlled release of the active compounds, promoting hair growth by stimulating keratin expression and supporting hair follicle health.

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A hair growth composition and liposome preparation method that addresses the challenges of traditional treatments for hair loss. The composition combines ligustrazine, panax notoginseng saponins, tanshinone oxime, thymol, adenosine, tripeptide-1 copper, and trisodium fructose diphosphate to promote hair growth from multiple directions. The composition is formulated into liposomes through a novel supercritical CO2 method that maintains the integrity of heat-sensitive ingredients while achieving precise control over formulation parameters. This approach enables a stable, bioavailable, and clinically effective hair growth treatment.

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A hair growth promoting peptide composition that enhances hair growth through synergistic action of multiple peptides. The composition comprises a polypeptide that stimulates collagen production and promotes keratin gene expression, with specific peptides including biotin tripeptide-1, copper peptides, and acetyl tetrapeptide-3. This peptide combination provides superior hair growth outcomes compared to individual peptides alone, with enhanced synergistic effects.

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