20 patents in this list

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Modern microneedling techniques create thousands of controlled micro-injuries in the dermis, typically penetrating between 0.5-2.5mm deep depending on the treatment area. These microscopic channels trigger the skin's natural wound healing response while providing pathways for enhanced topical product absorption—with studies showing up to a 300% increase in transdermal delivery efficacy.

The fundamental challenge lies in optimizing needle depth, density, and insertion velocity to maximize collagen induction while minimizing patient discomfort and recovery time.

This page brings together solutions from recent research—including vacuum-assisted delivery systems, retractable needle arrays, combined stimulation approaches using electrical and light energy, and precision-controlled penetration mechanisms. These and other approaches focus on improving treatment consistency and results while maintaining patient safety and comfort.

1. Skin Treatment Device with Recessed Micro-Needle Element and Pulsating Vacuum System

IONTO HEALTH & BEAUTY GMBH, 2023

A skin treatment device using micro-needling for cosmetic treatments like collagen stimulation without requiring specialized training or restrictions on intensity. The device has a handpiece with a recessed needle element that can be inserted into the skin. A pulsating vacuum is generated to draw the skin into the handpiece for treatment. The vacuum alternates between strong and light levels to prevent contamination. The recessed needle design prevents the skin from being pressed instead of pierced, especially on loose or bumpy areas.

2. Handheld Dermal Needle Array Device with Skin Penetrating Capability

SHU WANROU, 2023

A handheld device with rows of needles that stimulate the skin and pierce the outer layer to allow skin care products to be directly absorbed into the dermis. The device has a handle with a row of needles that can be pressed into the skin to puncture the top layer. This allows creams and serums to penetrate deeper into the skin when applied after using the device, bypassing the outer layer that normally prevents absorption.

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3. Handheld Device with Interchangeable Dual-Function Plates for Microdermabrasion, Micro-Needling, and Massage

SKIN AESTHETICS CO, 2023

Compact handheld device for home facial rejuvenation that combines microdermabrasion, micro-needling, and massage in a single system. It uses interchangeable dual-function plates with sections for exfoliating, needling, and massaging while supplying skincare products. A vacuum pump moves fluids and removes dead skin. Valves control operations.

4. Facial Microneedling System with Compound Infusion for Inducing Endogenous Skin Regeneration

HUBEI ZHENZHI MEDICAL BEAUTY CLINIC CO LTD, 2022

Endogenous regeneration and repair technique using facial microneedling to restore skin and combat signs of aging. The technique involves using fine needles to stimulate the skin's natural healing and regenerative processes. It involves cleaning the treatment area, numbing it, disinfecting, preparing a compound liquid of collagen, stem cells, hyaluronic acid, antioxidants, and saline, then injecting and penetrating the compound into the skin with the microneedles. This stimulates cell proliferation, contraction, and collagen production to smooth wrinkles, fill depressions, tighten skin, and promote overall rejuvenation.

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5. Micro Needling Device with Adjustable Needle Depth and Speed, Incorporating Ultrasound or RF Integration

NESBITT LESLIE, 2022

A micro needling device for skin care that uses sterile needles or natural mineral element needles to treat skin conditions like acne, scarring, hyperpigmentation, stretch marks, cellulite, and aging. The device has a digital interface with adjustable needle depth and speed settings. It can also optionally use ultrasound or RF to enhance treatment. The device is used in combination with skin care products containing ingredients like collagen, elastin, and antioxidants to address specific skin issues. The micro needling stimulates collagen production and improves product absorption. The device aims to provide more effective and customizable treatment for skin conditions compared to conventional micro needling devices.

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6. Cosmetic Skin Treatment Utilizing Microneedles for Nutrient Solution Delivery and Collagen Stimulation

SHANGHAI OUBANG MEDICAL MANAGEMENT CO LTD, 2021

A cosmetic method using small needles to resist skin aging without the need for repeated filler injections. The method involves injecting a nutrient-rich solution into specific aging areas using small needles. The needles create tiny wounds that stimulate collagen and elastin production to restore firmness. The nutrients also provide moisture to plump the skin. The repeated micro-injuries trigger self-repair and collagen production.

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7. Skin Treatment Needle with Wrinkled Conductive Surface for Uniform Electric Field Distribution

AGNES MEDICAL CO LTD, 2021

A skin treatment needle with uniform energy distribution to minimize damage to the epidermis and supply energy to various depths within the skin for faster healing. The needle has a conductive portion with wrinkles on its outer surface to form a differentiated electric field compared to the rest of the needle. This focused field avoids excessive concentration of energy in the epidermis. The wrinkles distribute the electric field more uniformly as the needle penetrates the skin. The wrinkled conductive portion is etched into the needle body by micromachining. An insulating coating covers the non-conductive parts of the needle. This allows targeted energy delivery at different depths without damaging the epidermis.

8. Skin Treatment Device with Polymeric Microneedles of Variable Dimensions and Integrated Vacuum Suction Mechanism

ALLERGAN INC, 2020

Skin treatment device with polymeric microneedles that more effectively deliver beneficial agents to skin compared to prior art microneedles. The microneedles are made of biocompatible, biodegradable polymers like hyaluronic acid. They have varying lengths and widths to better penetrate different facial areas with thicker or thinner dermis. The microneedles can also contain additives like vitamins for enhanced skin treatment. The device uses vacuum suction to draw skin into the array of microneedles.

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9. Skin Treatment Device with Biodegradable Polymer Microneedles and Variable Length Arrays

ALLERGAN INC, 2020

Skin treatment device with microneedles made of biodegradable polymers like hyaluronic acid for more effective delivery of beneficial agents into skin. The microneedles are customized for different skin areas based on dermal thickness. The device can have regions with microneedles of varying lengths to penetrate optimally in specific facial zones. It also provides a method of using suction to draw skin towards the microneedle array for easier penetration. The device can have detachable patches with customized microneedle arrays for personalized treatments.

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10. Cosmetic Device with Adjustable Nano-Penetration and Mobility Features

JIANGSU XUYIN BIOLOGICAL TECH CO LTD, 2019

A cosmetic device and method for skin care that provides deeper and more effective results compared to manual methods. The device has a body, handle, foot pedal, panel, and pen tip. It also has wheels to move around. The pen tip can accurately introduce nutrients into the skin layers using nano-penetrating pores. The device allows adjustable force and speed control via the pedal and handle. The pen tip can repair red blood cell genes for skin benefits like thickening, whitening, and de-yellowing. The wheels allow mobility for treatment versatility. The device aims to improve skin texture, pores, wrinkles, firmness, whitening, rejuvenation, and nutrient absorption compared to manual methods.

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11. Device and Method for Wrinkle Reduction via Multi-Outlet Needle Injection with Angled Subcutaneous Channel Formation

HANGZHOU LAIWEI MEDICAL BEAUTY CLINIC CO LTD, 2018

A method for removing wrinkles using a special device that injects liquid into the skin to stimulate collagen growth. The device has a needle with multiple outlets at different depths. It is inserted into the skin at an angle to open channels. A piston pushes the liquid out of the needle to peel off layers of skin. This creates subcutaneous wounds that promote collagen regeneration. The liquid can be saline, collagen, or hyaluronic acid.

12. Handheld Skin Treatment Device with X-Shaped Needle Tip and Epidermis-Dermis Junction Detection Sensors

BELLUS MEDICAL LLC, 2018

A device and method for collagen remodeling in the skin to improve conditions like scars and wrinkles without visible scarring. The device is a handheld tool that has a single-use needle module with a unique X-shaped tip. The X shape reduces the cross-sectional area of the needle at a given depth. The device also has sensors to detect the epidermis-dermis junction and a microprocessor to modulate the needle's depth, frequency, and power during operation. The X-shaped needle and depth sensing allow precise controlled microinjury to stimulate collagen remodeling in the dermis without scarring.

13. Microneedle Roller Device with Integrated Drug-Coated Needles and Reservoir Dispenser

PICOBIO CO LTD, 2018

A microneedle roller device for skin stimulation that allows drugs to be applied and injected into the dermis in a single step. The device has a roller with needles coated with drug. When the roller is rolled over the skin, the needles puncture the epidermis and the drug is injected into the dermis. A drug reservoir and dispenser attaches to the roller. It holds the drug and dispenses a precise amount when the roller is rolled. This ensures consistent drug delivery with each use. The roller and reservoir are removable for cleaning and refilling.

14. Skin Surface Area Reduction via Controlled Tensile and Compressive Stress Application on Micro-Perforated Tissue

VZE DZHENERAL KHOSPITAL KORPOREJSHN, THE GEN HOSPITAL CORP, General Hospital Corporation, 2018

Reducing skin surface area, like wrinkles, by forming a plurality of small holes in the skin and then applying tensile or compressive stresses during healing. The small holes, measuring around 0.2-0.7mm, are formed using coronoid biopsy needles. Applying stresses in a specific direction enhances the overall reduction of the treated area and provides a directed displacement of the contraction. The stresses are maintained until the holes close to prevent scarring. This method allows directed skin tightening without large scars compared to traditional surgery.

15. Mechanical Apparatus with Hollow Needles for Fractional Tissue Removal via Simultaneous Insertion and Withdrawal

THE GENERAL HOSPITAL CORP, 2017

Mechanical device and method for generating fractional tissue damage in skin to improve cosmetic appearance without thermal damage. The device has multiple hollow needles fixed on a block that can be inserted and removed simultaneously to create multiple small holes in the skin. The hollow needles remove tissue when inserted and withdrawn. This provides fractional tissue damage that promotes skin rejuvenation without scarring or infection compared to lasers. The device can have different needle sizes and shapes. A low pressure suction can assist needle insertion.

16. Soluble Microneedles Comprising Arbutin with Dissolvable Matrix for Enhanced Dermal Delivery

LG HOUSEHOLD & HEALTH CARE LTD, 2016

Soluble microneedles containing arbutin that effectively deliver the skin whitening agent into the skin while reducing irritation compared to traditional microneedles. The microneedles are made by dissolving arbutin in a skin-dissolving material like hyaluronic acid, sodium carboxymethylcellulose, or sugars. When applied to the skin, the microneedles dissolve or collapse, releasing arbutin into the skin. This allows arbutin to penetrate deeper compared to regular microneedles. The soluble microneedles also have lower skin irritation compared to solid microneedles.

17. Micro-Needle Roller with Fine, Short Needles for Transdermal Micro-Channel Creation

Shanghai Baihua Biotechnology Co., Ltd., SHANGHAI BAIHUA BIOLOGICAL TECHNOLOGY CO LTD, 2016

A painless, transdermal administration device for drugs and beauty products that allows rapid, efficient absorption into the skin without needles or injections. The device uses a micro-needle roller with very fine, short needles that penetrate the skin to create multiple micro-channels. This allows active ingredients in drugs and beauty products to be directly absorbed into the skin deeper layers, bypassing the outer layer. The roller is rolled over the skin to stimulate penetration. The roller design and material are optimized for painless use. The micro-needles are thin, short, and tightly spaced to minimize discomfort. The roller is also made of a special material that prevents bacteria from entering the needles. The roller can be used for painless drug delivery, wound healing, scar reduction, stretch mark removal, acne treatment, whitening, and anti-aging.

18. Method for Sequential Dermal and Epidermal Lesion Formation Using Laser-Induced Breakdown

KONINKLIJKE PHILIPS NV, 2015

Combined dermal and epidermal treatments to improve skin rejuvenation outcomes while reducing side effects like pain, downtime, and risks of complications. The method involves causing dermal lesions in the skin without epidermal damage, followed by separate epidermal lesions. This accelerates healing and remodeling of the dermis and skin as a whole compared to just dermal or epidermal treatments alone. It uses techniques like laser-induced breakdown to avoid damaging the epidermis while creating dermal lesions.

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19. Skin Stimulator with Detachable Multi-Needle Tip Featuring Variable Needle Dimensions and Configurations

???, 2012

Skin stimulator for improving skin conditions like acne scars, stretch marks, and pore size by increasing collagen and elastin production. The stimulator has a handle with a detachable tip containing multiple fine needles. The tip attaches to the handle via a base with predefined needle positions. The needles have different diameters and lengths to target different skin layers. The stimulator is used by pressing the tip into the skin to create micro injuries that promote collagen and elastin synthesis. The detachable tip allows customization of needle configuration.

20. Device for Skin Perforation with Reciprocating Needle Array and Integrated Drug Delivery System

???, MCURE CO LTD, 2009

Skin reproduction device using a multi-hole technique for minimally invasive drug delivery and skin treatment. The device quickly creates multiple fine holes in the skin using a reciprocating needle array. Drugs are then delivered into the holes using a pressurized syringe or spray gun. The device aims to reduce pain, increase drug absorption, and enable rapid treatment of areas like the face and scalp. A cart with control components manages the device's linear motion and air pressure. The device also has features to limit needle depth and replace worn needles.

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