Probiotic Integration in Skincare Formulations

A composition for regulating skin microecological balance that promotes healthy skin by improving skin microbiome diversity. The composition contains five ingredients: lactobacillus/soybean milk fermentation product filtrate, inulin, alpha-glucan oligosaccharides, red pine leaf extract, and lactobacillus fermentation product. The ingredients synergistically promote probiotic growth, inhibit harmful bacteria, eliminate biofilms, and reduce quorum sensing to achieve overall skin microbiome balance. The composition is useful in skin care products to enhance skin barrier, control oil, relieve irritation, and repair skin.

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Composition for improving skin elasticity, skin regeneration, and pore shrinkage through the synergistic effects of three strains of lactic acid bacteria (Lactobacillus subtilis TIMMAY, Lactobacillus rhamnosus PINKBLAC, and Leuconostoc mesenteroid ELASTIC) that exhibit enhanced skin conditions. The composition combines these strains in a complex extract to deliver a potent combination of skin elasticity enhancement, wound regeneration, and pore contraction properties.

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Lactobacillus composition for skin care products that inhibits Staphylococcus aureus adhesion and prevents skin infections. The composition contains specific strains of Lactobacillus, particularly Lactobacillus reuteri and Lactobacillus salivarius, which exhibit enhanced adhesion inhibition capabilities compared to other strains. These strains can prevent S. aureus colonization and reduce its virulence factors, including coagulase, PVL, and exfoliative toxins, thereby protecting the skin barrier and preventing skin conditions like atopic dermatitis.

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Lactobacillus plantarum TWK10 improves skin health through its anti-aging properties. The probiotic strain, which is a new taxonomy designation for Lactobacillus plantarum TWK10, has been found to prevent skin aging by reducing oxidative stress and inflammation. It achieves this through its ability to regulate skin oxidative stress, inflammatory response, and signaling pathways, particularly by inhibiting key enzymes involved in collagen degradation and cell membrane damage. The probiotic can be used in food and cosmetic formulations to prevent and treat skin aging, while also having potential applications in preventing and treating skin diseases like eczema and psoriasis.

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Combining extracts of the plant Polygonum aviculare with synbiotics (probiotics and prebiotics) in specific ratios for dermatological and cosmetic applications. The compositions provide improved skin health benefits compared to using Polygonum extracts or synbiotics alone. The ratios of Polygonum extract to synbiotics range from 10,000:1 to 1:10,000. The compositions can be formulated into creams, gels, lotions, sprays, patches, etc. for skin conditions like eczema, acne, atopy, inflammation, aging, etc. The Polygonum extract and synbiotics synergy provides benefits beyond what each component alone could achieve.

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A topical skin composition for maintaining healthy skin microbiota through direct application of beneficial bacteria. The composition comprises live Lactobacillus strains, specifically Lactobacillus plantarum with at least 97% sequence similarity in its 16S rRNA gene to 5F, which is particularly effective in restoring and maintaining a healthy skin microbiota. The composition is particularly suited for treating skin conditions associated with microbial imbalances, such as acne, athlete's foot, and fungal infections.

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A probiotic postbiotic composition that enhances skin barrier function and reduces allergic reactions through synergistic action of probiotic metabolites. The composition combines inactivated probiotic cells with their metabolites, which are rich in bioactive compounds like organic acids and short-chain fatty acids. This formulation enhances barrier repair, reduces inflammation, and promotes immune tolerance, making it particularly effective in treating skin allergies.

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Cosmetic composition containing a culture of the skin-derived lactic acid bacterium Lactobacillus plantarum HDB (Lactobacillus plantarum HDB, KCCM13182P) strain. The composition enhances skin moisture density and reduces transepidermal water loss by selectively regulating the moisture-friendly skin microbiome. The culture increases expression of proteins responsible for skin barrier and moisturization. It strengthens the skin barrier, increasing skin moisture content, and activates only moisture-friendly microbes. The composition can be used in creams, essences, lotions, and infusion waters to improve skin condition.

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A ternary probiotic factor composition for regulating skin microecological balance and its preparation method and use. The composition contains probiotics, prebiotics, and postbiotics. It aims to promote beneficial skin flora, improve skin health, and maintain a balanced microbiome. The probiotics are grown using prebiotics as nutrients. The composition can be used in cosmetics to regulate skin microbiota.

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A method and system for enhancing the skin microbiome through targeted skin contact formulations containing beneficial bacteria and other microbe components. The method involves administering a specific skin formulation containing beneficial bacteria and other microbe components to a newborn's skin, specifically within the first 6 hours of birth. This targeted approach enables the establishment of a healthy skin microbiome through early exposure to beneficial microorganisms, which is critical for immune system development and preventing skin diseases. The formulation is specifically designed to address particular skin concerns, such as acne, and can be administered through various delivery methods, including lotions, ointments, and sprays.

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Composition containing probiotics, particularly Lactobacillus, for preventing and treating inflammatory skin diseases like atopic dermatitis through modulating the skin microbiome. The composition, which can be used in topical formulations, employs a combination of probiotic strains that exhibit immunomodulatory effects on keratinocytes, particularly those involved in inflammation. The probiotics enhance the skin's natural barrier function and promote the restoration of the skin microbiota balance, thereby mitigating disease progression.

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Enhancing the health of an individual's skin microbiome to improve skin health through the use of modified bacteria and other skin contacting formulations. The method involves administering modified bacteria with desirable characteristics to specific skin regions, like newborns within hours of birth. The bacteria may be human-specific strains modified to reduce pathogenicity or enhance beneficial functions. Prebiotics and extracts are also applied to support the modified bacteria. The goal is to balance skin microbes for better skin health and disease prevention.

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A skin care composition that promotes skin microbiome balance through growth-enhancing compounds. The composition comprises a carbon source, such as pyruvic acid, pyruvate, lactic acid, lactate, or a combination thereof, along with a nitrogen source like urea or arginine, and a lipid source like caprylic/capric triglycerides. These components are combined in a skin care formulation that supports the growth of beneficial skin microorganisms, maintaining a healthy skin microbiome balance.

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A cosmetic treatment that utilizes Lactobacillus crispatus to reduce skin and mucous membrane pigmentation and prevent hyperpigmentation. The treatment involves applying a strain of Lactobacillus crispatus, specifically CNCM 1-5579, to the affected areas of the skin and mucous membranes. This strain has been found to inhibit melanin synthesis and prevent excessive melanin deposition, thereby reducing the appearance of hyperpigmentation and preventing its progression. The treatment can be applied topically in various forms, including powders, sticks, and lip balms, and can be used to treat phototype IV to VI skin.

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A probiotic composition comprising Lactobacillus plantarum, Lactobacillus rhamnosus, and Lactobacillus reuteri, which is effective in preventing and treating inflammatory, autoimmune, and allergic skin diseases. The composition combines these three probiotic strains in a synergistic manner, with Lactobacillus plantarum providing a broad-spectrum probiotic effect, Lactobacillus rhamnosus enhancing immune modulation, and Lactobacillus reuteri addressing specific skin barrier and immune system challenges. The composition is particularly beneficial for conditions like atopic dermatitis and acne, where these strains have been shown to exhibit potent anti-inflammatory and antimicrobial effects.

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Compositions containing probiotics for preventing and treating skin disorders like atopic dermatitis. The compositions contain specific strains of lactic acid bacteria like Lactobacillus paracasei and Lactobacillus acidophilus. These probiotics have anti-inflammatory and immunomodulatory effects on skin cells. The compositions can also contain amino acids, vitamins, minerals, enzymes, and prebiotics to support skin health.

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A probiotic composition that selectively targets and inhibits pathogenic bacteria while promoting beneficial microbial growth, enhancing skin barrier function, and regulating inflammation. The composition contains a specific strain of Lactobacillus plantarum and Lactobacillus fermentum, which exhibit enhanced antimicrobial activity against Staphylococcus aureus and Propionibacterium acnes compared to their single bacterial counterparts. The composition also exhibits potent antioxidant activity, up-regulates barrier repair genes, and modulates inflammatory responses.

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A composition comprising a lactic acid bacteria complex strain as an active ingredient, and more specifically, Bacillus (Bacillus sp.) pfbarrier 01 (KCTC 14628BP), Lactobacillus Pentosus (Lactobacillus pentosus) pfbio035 (KCTC 14684BP) and Lactobacillus sake (Lactobacillus sakei subsp.sakei) It relates to a composition comprising three complex strains of pfbio005 (KCTC 14130BP), a culture thereof, or a complex extract thereof as an active ingredient, and showing skin wrinkle improvement, moisturizing, skin barrier strengthening, and skin wound regeneration activity.

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Antioxidant, anti-inflammatory and whitening cosmetic composition that can be used for the production of functional cosmetics and functional foods. The composition includes lactic acid bacteria derived from human skin having antioxidant, anti-inflammatory or whitening activities.

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A skin care composition that promotes the development of a healthy skin microbiome through targeted application of growth-enhancing compounds that support the growth of beneficial microorganisms in the skin microbiome. The composition contains a carbon source, such as glucose, fructose, or pyruvic acid, and a nitrogen source, such as arginine, that are metabolized by microorganisms in the skin microbiome, thereby supporting their growth. The composition also contains a lipid source, such as caprylic/capric triglycerides, to support the growth of microorganisms. The composition maintains a low osmolality of 4000 mOsm/kg of water or less, which is crucial for bacterial metabolism and viability.

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