Methods for Follicular Stimulation and Hair Growth

Dual-wavelength laser system for hair loss treatment that uses lasers at two specific red wavelengths (650nm and 780nm) to stimulate hair follicles at different depths. The system has a placement seat with an operating table, laser arm, disinfectant storage box, and refrigerator. The laser device has a dual-wavelength laser diode, disinfectant nozzle, and air delivery pipes to spray iodine between treatments. It also has refrigerated air delivery to keep the treatment area cool.

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Compositions and methods for stimulating hair growth and treating hair loss using a compound called squaric acid di(trifluromethyl)propyl ester (CF3-SADBE). The compound is applied topically to hair follicles to increase hair growth and transition to the active anagen phase. It can also be used to treat hair loss beyond autoimmune alopecia conditions like alopecia areata. The compositions can include CF3-SADBE, diphenylcyclopropenone (DPCP), or a combination, along with other hair growth agents.

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Promoting hair growth and treating hair disorders like alopecia by inhibiting mitochondrial pyruvate oxidation in cells using compounds like JXL001. The compounds inhibit mitochondrial pyruvate carriers like MPC1. This enhances lactate production and LDH activity, which promotes hair growth. Administering the compounds topically or systemically can treat hair disorders.

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Composition for preventing hair loss and promoting hair growth containing specific natural compounds. The composition contains one or more of gypsogenin 3-O-β-D-glucuronopyranoside, deapioplatycodin D, congmunoside X, and chikusetsusaponin IVa as active ingredients. These compounds inhibit male hormone activity and suppress expression of a hair follicle catagen factor to transition hair growth from the shedding phase to the growth phase. The composition can be used in products like shampoo, tonic, lotion, hair oil, and functional foods to prevent hair loss and promote hair growth without side effects.

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Laser treatment to stimulate hair growth, regenerate damaged hair, prevent hair loss, and increase hair density. The method involves laser irradiation of hair follicles using a specific laser wavelength (1565 nm) to promote hair growth and improve hair quality. The laser treatment is done on areas of the scalp with thinning or missing hair to stimulate follicles and restore growth.

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Dual-mode laser hair growth device that combines focused laser acupuncture and diffused laser therapy to improve effectiveness for treating hair loss. The device has a head-worn body with separate assemblies emitting a focused laser for acupuncture and a diffused laser for scalp irradiation. This allows simultaneous targeted stimulation of acupuncture points and whole-head hair follicle activation for enhanced hair growth treatment compared to single-mode lasers.

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Modulating hair growth and activating hair follicle stem cells to treat hair loss conditions by targeting the Gas6-Tyro3/Axl/Mertk (TAM) signaling pathway. The method involves administering agents that increase Gas6 expression or activation, inhibit BMP signaling, or activate AXL to stimulate hair growth and stem cell activation. Alternatively, agents that decrease Gas6 expression, activate BMP signaling, or inhibit AXL can be used to decrease hair growth and stem cell activation. This provides a way to enhance or inhibit hair growth and stem cell activity as a therapy for hair loss conditions like telogen effluvium.

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Hair growth stimulant compound that promotes hair growth without affecting male hormone activation. The compound is represented by chemical formula 1: (R in formula 1 is hydrogen, hydroxyl, or methoxy). It promotes hair papilla cell proliferation, vascular endothelial growth factor (VEGF) production, and beta-catenin production. This compound can be used in hair growth products like cosmetics, quasi-drugs, and pharmaceuticals to promote hair growth and prevent hair loss without the side effects of hair loss drugs that suppress male hormone activation.

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Applicator for ameliorating alopecia, improving hair quality, and scalp condition using lasers. The applicator has multiple output points spaced close together to deliver laser light through hair. It splits a main laser beam into multiple partial beams using apertures or lenses. This allows targeted hairless skin treatment while avoiding excessive hair absorption. The close spacing prevents full hair coverage between points. This enables equal scalp coverage and repeatable protocols compared to spot-by-spot manual parting.

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Composition for promoting hair growth and/or improving white hair containing 2-O-ferloyl-L-malic acid. The compound is extracted from watercress and found to promote hair growth and/or reduce white hair by increasing R-spondin1 production in dermal papilla cells.

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Using electromagnetic fields to activate dermal papilla cells and promote hair growth, preventing or improving hair loss. The method involves treating hair follicles with an electromagnetic field having a frequency of 70 Hz and intensity of 10 G for 1 hour. This activates dermal papilla cells and promotes hair growth without apoptosis, preventing alopecia. The specific electromagnetic field parameters of 70 Hz frequency and 10 G intensity for 1 hour were found to increase dermal papilla cell activity and hair follicle growth.

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A composition for preventing hair loss and promoting hair growth containing specific plant-derived compounds. The composition includes at least one of Momordin Ic, Praticodin D2, Polygalacin D, Asiaticoside B, Bacopaside I, Notoginsenoside R2, Picfeltarraenin IB, Pseudoginsenoside RT5, Raddeanin A, Vina-ginsenoside R4, and Lipoglycoside II. These compounds enhance dermal papilla cell activity, promote mitochondrial activity, amplify Wnt/beta-catenin signaling, and inhibit male hormone action.

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A portable, compact, and easy-to-use device for home use of low-level laser therapy to treat hair loss. The device has a compact form factor and can be easily carried around. It provides convenient and accessible laser hair growth treatment for individuals with hair loss. The device is designed to deliver low-level laser therapy to stimulate hair growth. It uses LED diodes emitting light in the near-infrared spectrum to penetrate the scalp and promote cell metabolism, blood circulation, and collagen synthesis. The device is FDA-approved for hair loss treatment and provides an effective alternative to invasive hair transplants or medications. The device aims to improve hair growth and density by delivering targeted laser therapy in the comfort of one's home.

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A helmet for preventing hair loss using low-level laser therapy (LLLT) to stimulate hair growth. The helmet has LEDs arranged in a specific pattern on the inner skin to irradiate the scalp. The LEDs generate multiple wavelengths within 610-900nm. The LED arrangement forms hexagonal modules with a central LED surrounded by 6 peripheral LEDs. This configuration maximizes hair growth effects by increasing blood flow to the follicles, stimulating micronerves, muscles, and follicles, and penetrating laser light to multiple follicles.

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Promoting hair growth using compounds derived from papaya fermentation. The compounds, isopropyl 2,5-dihydroxybenzoate and related derivatives, are found in papaya fermented products. They promote hair growth when applied to the skin. The compounds can also be used as antioxidants. The papaya fermentation process involves steps like crushing papaya, adding sugar, aging, and fermenting.

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A light source device for hair growth that improves the efficiency and uniformity of low-level laser therapy for hair regrowth compared to existing devices. The device has a light source in a sleeve with a shaping element inside to shape the emitted light. This element has a wedge-shaped groove that gradually narrows towards the center. The shaping element focuses and directs the light from the source towards the scalp in a more concentrated and uniform pattern. It reduces scattering and blocking by surrounding hair, improving laser utilization and efficacy.

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Accelerating hair growth by targeting hair follicle stem cells (HFSCs) using a specific lactate dehydrogenase (LDH) isoform. The compound is a LDH inhibitor that selectively blocks LDH activity in HFSCs. Administering this compound to mice accelerates hair growth, improves hair thickness, and prevents hair loss. It does this by activating HFSCs and promoting their entry into the hair cycle. The compound selectively inhibits LDH in HFSCs without affecting LDH in other cells. This selectivity is achieved by targeting a specific LDH isoform (LDHA) expressed in HFSCs.

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Phototherapy device for promoting hair growth using pulsed light to activate hair follicle stem cells and induce hair follicle differentiation. The device is a light patch attached to the scalp that emits specific wavelengths of light in a fixed mode to stimulate hair growth. The patch has LEDs with wavelengths of 590-680nm arranged in a pattern on a flexible circuit. A control module regulates the LED brightness and timing.

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Promoting hair growth using compounds found in papaya fermented products. The compounds, isopropyl 2,5-dihydroxybenzoate and related derivatives, have an effect of promoting hair growth when applied to the skin. The compounds can be isolated from papaya fermented products, or the fermented products themselves can be used. They can also be used to make antioxidant compositions or functional foods for hair growth.

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A laser hair growth device using curved illuminating fibers to more uniformly irradiate the scalp with low-power lasers for hair growth promotion. The device has a laser source, curved illuminating fibers arranged in a special pattern, and a helmet-like structure to hold the fibers against the scalp. The curved fibers emit laser light from the scalp surface to stimulate hair growth. The fiber curvature conforms to the head shape for even coverage. The device aims to provide more consistent and effective laser hair growth compared to direct-mounted lasers on helmets or combs.

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