Ultrasonic Methods for Dermal Matrix Restructuring
56 patents in this list
Updated:
Ultrasonic dermal treatments operate within precise acoustic parameters, delivering energy at frequencies between 10 kHz and 50 MHz to achieve tissue temperatures of 40-65°C at depths up to 3mm. These interventions must carefully balance energy delivery with tissue response, as excessive thermal elevation or mechanical stress can lead to unintended damage in surrounding structures.
The fundamental challenge lies in achieving targeted matrix restructuring while maintaining the integrity of adjacent tissue layers and managing the complex interactions between ultrasonic waves and varying dermal compositions.
This page brings together solutions from recent research—including sequential RF-ultrasound combinations, moisture-responsive intensity modulation systems, multifocal transducer arrays, and active ingredient-enhanced transmission methods. These and other approaches focus on optimizing treatment efficacy while preserving tissue safety and patient comfort.
1. Skin Treatment Device with Sequential RF Heating and Focused Ultrasound Coagulation Mechanism
LUTRONIC CORP, Lutronic Corporation, 2024
Skin treatment device using focused ultrasound and RF energy to shorten treatment time and increase recovery effect. The device uses RF energy to heat the treatment area to a temperature that increases ultrasound transmission efficiency. Then focused ultrasound is applied to coagulate the tissue. This two-step process improves ultrasound penetration and cell activity while avoiding excessive damage.
2. Method Utilizing Low-Energy Ultrasound and Cosmetic Active Medium for Skin Surface Treatment
OREAL, 2024
Less invasive method for reducing wrinkles on the skin surface using a combination of a medium containing cosmetic actives and ultrasound waves with lower energy than high intensity focused ultrasound (HIFU). The method involves applying the medium to the skin and then delivering focused or unfocused ultrasound waves through it. The ultrasound waves propagate into the skin to depths of 3 mm and produce localized temperature increases of 40-65°C for short periods. The lower energy ultrasound is more tolerable on the skin compared to HIFU. The actives in the medium improve wrinkles when combined with the ultrasound.
3. Ultrasonic Skin Treatment Device with Adjustable Energy Levels and Delivery Patterns for Targeted Tissue Modulation
JEISYS MEDICAL INC, 2023
Ultrasonic skin treatment device that selectively provides fat reduction, fat increase, or elasticity enhancement based on applied ultrasound energy levels and patterns. The device uses a specialized control unit that enables targeted fat reduction, fat increase, or elasticity enhancement by applying specific ultrasonic energy levels to the skin layers. The device can use dot or linear ultrasound delivery methods to focus energy at varying depths and move horizontally. It applies energies like 0.1-0.3J to increase fat, 0.2-0.6J to reduce fat, and 0.2-0.6J to boost elasticity. By tailoring ultrasound dosage and patterns, the device aims to avoid tissue damage and promote selective fat, elasticity, or both changes.
4. HIFU Device with Skin Moisture-Responsive Intensity Modulation and Detachable Ultrasound Cartridge
ADC CO LTD, 2023
High intensity focused ultrasound (HIFU) device for skin treatments that improves efficiency and stability by varying the ultrasound intensity based on skin moisture levels. The device has a detachable ultrasound cartridge that outputs focused ultrasound to the skin. A control module in the handpiece measures skin moisture using sensors and adjusts the ultrasound cartridge's driving power amplitude. The cartridge then changes the ultrasound intensity accordingly. This allows customized treatment intensity based on skin hydration to enhance effectiveness and minimize discomfort.
5. Ultrasound Device with Multifocal Transducer Emitting Variable Amplitude and Work Cycle for Subcutaneous Tissue Treatment
SAENZ JULIA JOSE MANUEL, 2023
Ultrasound device for selective treatment of subcutaneous tissue like adipose and connective tissue to rejuvenate and reshape the body without cell death or burns. The device has a multifocal ultrasound transducer that emits a low intensity, low frequency sound field with varying amplitude and work cycle. This focuses energy over a wider area than conventional ultrasound, reducing metabolic load and permeability to induce physiological lipolysis and tissue remodeling without saturation. The multifocal beam avoids cell death and cavitation effects. The device excites at frequencies selective to fat diameters and uses long off-times between bursts to expel heat.
6. Non-Invasive Skin Treatment Using Ultrasonic Waves with Active Ingredient-Infused Medium
OREAL, 2023
Reducing wrinkles on the skin using a non-invasive method that combines a medium containing cosmetic actives with ultrasonic waves. The method involves applying a medium with active ingredients like hyaluronic acid to the skin, then applying focused pulsed ultrasonic waves to propagate through the skin. This method aims to improve wrinkles without invasive needles or injections. The ultrasonic waves can be customized to generate local temperature rises in the skin. The medium with active ingredients enhances the effects of the ultrasound on the skin.
7. Skin Treatment System Utilizing Cosmetic Medium with Low-Energy Ultrasound Wave Application
LOREAL, 2023
Reducing wrinkles on the skin using a combination of a cosmetic medium and low-energy ultrasound waves. The method involves applying a medium containing cosmetic actives like hyaluronic acid, peptides, and ceramides to the skin. Ultrasound waves with frequencies between 10 kHz and 50 MHz are then applied to the skin through the medium. The ultrasound waves propagate into the skin to depths up to 3 mm, generating localized temperature rises. This less-invasive approach improves wrinkles by combining cosmetic benefits from the medium with targeted skin heating from the ultrasound.
8. Hands-Free Ultrasonic System with Fixed Panels and Neural Network-Driven Depth Control for Skin and Fat Treatment
INES VERNER RASHKOVSKY, 2022
A hands-free ultrasonic skin tightening and body contouring system that provides effective treatment of both skin laxity and fat deposits in a single device. The system uses fixed treatment panels that wrap around body organs like the abdomen. Ultrasound imaging is used to determine the correct depth for treatment. The system has temperature sensors on the panels to monitor the skin and fascia during treatment. A neural network algorithm computes the depth indication. The ultrasound energy heats the subcutaneous fat and fascia while keeping the epidermis cooled below damaging temperatures. The system aims to achieve both tightening and contouring in one device with precise depth control and visualization.
9. Focused Ultrasound System with Movable Transducer Applicator and Integrated Cooling Mechanism
SOFWAVE MEDICAL LTD, 2022
A system for treating skin using focused ultrasound to reduce wrinkles and tighten skin. The system includes an applicator with multiple ultrasound transducers that can be moved across the skin to emit unfocused ultrasound energy. The applicator also has cooling capabilities to prevent thermal damage to the skin surface. The system can personalize treatment parameters like energy intensity and duration based on factors like skin composition, wrinkle depth, and pain sensitivity. The goal is to deliver safe, effective ultrasound skin treatments without damaging nerves or causing excessive pain.
10. Ultrasound System with Multiplexed Focal Area Control for Cosmetic Treatment
ULTHERA INC, 2021
A system and method for non-invasive ultrasound cosmetic treatments that can safely and effectively perform various processing and imaging procedures to induce visible and effective cosmetic results via thermal pathways. The system allows separating the ultrasound treatment beam into multiple focal areas to treat multiple cosmetic areas simultaneously or sequentially. It uses techniques like amplitude modulation, phase shift, and polarization to dynamically control the number, shape, size, and thermal state of the treatment areas over time. The system has an ultrasound probe with a transducer, switches, and a moving mechanism to guide the focal points in sequences. It can apply ultrasound therapy to tissues at multiple locations at depth of focus.
11. Portable Ultrasonic Stimulator with Alternating Low and High Frequency Output for Variable Skin Interaction
SU GUN LEE, 2021
Portable ultrasonic stimulator that provides a high skin-tightening effect by alternately outputting low-frequency ultrasonic waves with high temperature rise in skin and high-frequency ultrasonic waves to degrade skin aging materials. The device has a controller that adjusts the frequency of current output over time to alternately provide low and high frequency ultrasonic waves. This allows using a single device to provide both skin tightening effects using ultrasonic waves of different frequencies.
12. Ultrasound Skin Treatment System with Adaptive Transducer Control and Impedance Monitoring
SOFWAVE MEDICAL LTD, 2021
Ultrasound skin treatment system that improves efficiency and reliability of the applicator by monitoring and adjusting performance over time. The system has a control console and an applicator with multiple ultrasound transducers. The console can activate and deactivate the transducers separately, measure impedance on each, and detect relative changes. If changes exceed a threshold, it modifies treatment parameters like frequency, amplitude, or transducer activity. This adapts treatment to maintain effectiveness as transducer performance degrades. The applicator has features like isolated wiring, sealing fluid, and printed circuitry between transducers to prevent fluid ingress and isolate electrical circuits.
13. Skin Treatment Device with Integrated Ultrasound and High Frequency Units Featuring Replaceable Cartridges and Adjustable Ultrasound Focal Length
Ecodm Lab Co., Ltd., ECO DM LAB Co., Ltd., 2020
Skin beauty device that combines ultrasound and high frequency for more effective skin treatment. The device has replaceable cartridges for both ultrasound and high frequency units. The ultrasound unit has a contact area on the skin surface, and the high frequency unit surrounds it with contact areas. This allows applying both modalities simultaneously to the same skin region. The ultrasound cartridge can adjust the focal length by varying the distance from the skin. This maximizes the combined effects of ultrasound and high frequency for penetration and collagen regeneration.
14. Skin Care Device with Ultrasonic Oscillator and Electrical Stimulation Unit
ELIMTEK CO LTD, 2020
A skin care device that combines ultrasonic waves and electrical stimulation to improve skin moisture, elasticity, regeneration, and anti-inflammation by increasing permeation. The device has a main body with an ultrasonic oscillator generating different ultrasonic wavelengths. The handpiece contacts the skin and selects the wavelengths. It also has an electrical stimulation unit with a temperature sensor, chip, and electrode pad to change the skin's electrical environment and promote cell metabolism.
15. Method for Enhancing Epidermal Drug Delivery via Ultrasound-Induced Cavitation with Specific Pressure and Duty Cycle Parameters
BIO INFRA LIFE SCIENCE INC, Bioinfra Life Science, 2020
A method to increase cell viability in the skin using ultrasound irradiation and drug delivery. The method involves applying a drug and epidermal delivery system to the skin, followed by ultrasound irradiation at specific parameters. The ultrasound pressure is 0.5-1 MPa and duty cycle is 1-5%. This promotes drug absorption into the skin without side effects. The ultrasound parameters were optimized to generate cavitation in the epidermis and enhance drug delivery. Redensyl, a hair growth drug, was used as an example. The ultrasound irradiation apparatus positions the ultrasound generator near the skin to deliver the optimized ultrasound parameters.
16. Ultrasound Irradiation Method with Specific Parameters for Enhanced Cell Survival
BIO INFRA LIFE SCIENCE INC, Bioinfra Life Science, 2020
Non-invasive, painless method to increase cell survival by irradiating ultrasound without drugs. The ultrasound parameters are critical to avoid damage: pressure 0.5-1 MPa, duty 1-5%, intensity 167-417 mW/cm2, frequency 0.5-4.6 MHz, duration <10 min. The ultrasound generator is positioned near the epidermis. It increases cell viability without side effects compared to drugs.
17. Method for Enhancing Cell Viability via Low Intensity Ultrasound with Specific Pressure and Duty Cycle Parameters
BIOINFRA LIFE SCIENCE INC, 2020
Method to increase cell survival using low intensity ultrasound irradiation for applications like wound healing. The technique involves delivering ultrasound with specific parameters to the epidermis to enhance cell viability. The ultrasound pressure is 0.5-1 MPa and duty cycle is 1-5%. The irradiation time is less than 10 minutes. This non-invasive, painless method can be used to improve cell survival without side effects in short application times. It can potentially be applied to treat wounds and promote hair growth using low intensity ultrasound.
18. Handheld Ultrasound Probe with Targeted Subcutaneous Energy Delivery and Wireless Control
GUIDED THERAPY SYSTEMS L L C, Guided Therapy Systems, LLC, 2020
Improving skin appearance using ultrasound energy to non-invasively enhance skin quality. The method involves delivering ultrasound to subcutaneous tissue beneath the skin surface to create biological effects. This improves aspects like elasticity, pore size, texture, hyperpigmentation, scars, collagen, wrinkles, and sagging. The ultrasound avoids avoiding interstitial tissue to maximize efficacy. The system is a handheld probe with an ultrasonic transducer, controller, and wireless interface for targeted treatment.
19. Ultrasound Therapy System with Digital Resonance Frequency Control and Mist Delivery Mechanism
ALLIQUA BIOMEDICAL INC, 2019
Non-contact, low-frequency, highly efficient ultrasound therapy system that delivers ultrasonic therapy treatments via a mist to a patient wound to promote wound healing. The system uses digital controls to maintain the ultrasound driver at the resonance frequency of the transducer. This allows efficient operation near the resonance point without the stability issues of analog controls. The digital frequency generator and phase detector are used to lock the frequency at resonance. This provides safe, portable, and accessible ultrasound therapy that can be used in homecare settings without specialized oversight.
20. System with Integrated Diagnostic and Therapeutic Ultrasound for Targeted Skin Treatment
ANGELSEN BJOERN A J, 2019
A system for treating wrinkles and rejuvenating skin using focused ultrasound therapy. The system uses a diagnostic ultrasound component to image the skin depth and determine optimal therapy locations. It then applies focused ultrasound foci at those locations using a therapeutic component. This allows personalized treatment based on skin thickness. The diagnostic component can also measure tissue parameters during therapy to optimize energy deposition. The system aims to provide more effective and customized ultrasound skin rejuvenation by leveraging diagnostic ultrasound for planning and monitoring.
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