Formulations for Blackhead Dissolution and Inhibition
26 patents in this list
Updated:
Blackhead formation occurs when sebum and dead skin cells accumulate and oxidize in follicular openings, creating visible dark plugs typically 1-3mm in diameter. Traditional extraction methods achieve only temporary results, with 60-70% of blackheads recurring within 6 weeks due to continued sebum production and incomplete removal of follicular debris.
The challenge lies in developing formulations that can both dissolve existing comedones and prevent new formation while maintaining the skin's protective barrier function.
This page brings together solutions from recent research—including mild acidic cutin softeners combined with natural extracts, biopolymer-based delivery systems, and lipophilic formulations designed for follicular penetration. These and other approaches focus on achieving sustained results through combinations of active ingredients that address both immediate removal and long-term prevention.
1. Single Unit Dosage Form Combining Benzoyl Peroxide, Azelaic Acid, Strontium, and Methylsulfonylmethane
NOON AESTHETICS M R LTD, 2024
Combination therapy for treating dermatological conditions through a single unit dosage form that combines benzoyl peroxide, azelaic acid, strontium, and methylsulfonylmethane (MSM) for the treatment of acne and rosacea. The formulation delivers both benzoyl peroxide and azelaic acid in a synergistic combination, while simultaneously inhibiting neurogenic inflammation through strontium and MSM. This results in improved efficacy and reduced side effects compared to conventional treatments. The formulation can be delivered in various dosage forms, including creams, gels, and sprays, and is suitable for patients with sensitive skin.
2. Cosmetic Composition with Mild Acidic Cutin Softener and Natural Extracts for Blackhead Dissolution
AIYU COSMETICS JIANGSU CO LTD, 2023
Cosmetic composition for removing blackheads and a preparation method thereof. The composition includes a mild acidic cutin softener that loosens cutin in the stratum corneum, allowing subsequent penetration of natural plant extracts into pores and further softening and dissolving blackheads. The composition combines a mild, non-irritating cutin softener with natural extracts like Sapindus Mukurossi Extract, which effectively dissolves blackheads while maintaining skin health.
3. Composition of Plant Extracts and Natural Moisturizers with pH-Balanced Matrix for Blackhead Removal
MEIZHIEN SHANGHAI BIOTECHNOLOGY CO LTD, 2023
A natural blackhead removal composition that effectively removes blackheads without irritation, using a combination of plant extracts, natural moisturizers, and skin conditioners. The composition contains extracts from Angelica dahuricae, Horse Chestnut, seaweed, geranium, and Ginkgo, along with natural moisturizers, emollients, and skin conditioners. The composition is formulated with a pH-balanced matrix to deliver gentle, long-lasting results.
4. Cosmetic Composition with Succinic Acid, Fumaric Acid, 1,2-Hexanediol, Witch Hazel Water, and Glycerin and Method of Preparation
Guangzhou Shifei Biotechnology Co., Ltd., GUANGZHOU SHIFEI BIO-TECH CO LTD, 2023
A rapid blackhead removal composition and preparation method for cosmetics that effectively removes blackheads and aging cutin while controlling oil production and maintaining skin moisture. The composition combines a unique blend of natural ingredients, including succinic acid, fumaric acid, and 1,2-hexanediol, with witch hazel water and glycerin to create a potent, non-irritating cleanser. The preparation method involves combining the ingredients in a specific ratio and processing them in a controlled manner to deliver the active ingredients to the skin surface. The composition achieves rapid blackhead removal without causing secondary skin damage, making it suitable for daily use.
5. Salicylic Acid Composition with Natural Adjuvants Including Dimethyl Capric Acid Amide for Enhanced Solubility and Stability
BLOOMAGE BIOTECHNOLOGY CORPORATION LTD, 2023
Salicylic acid composition and its application for cosmetics, particularly in acne treatments, that addresses the limitations of traditional formulations. The composition comprises salicylic acid and a specific blend of natural adjuvants, including dimethyl capric acid amide, which enhances solubility and stability of the active ingredient. This formulation enables prolonged release of salicylic acid, providing sustained skin benefits, while maintaining its effectiveness against acne and skin conditions.
6. Biopolymer-Based Nasal Patch Composition with Natural Acid and Plant Extract for Blackhead Removal
GUANGZHOU XUZHUANG BIOLOGICAL TECH CO LTD, 2023
A composition and preparation method for removing blackheads that significantly reduces irritation to the skin. The composition comprises a film-forming agent, acid, anti-allergic agent, and moisturizer components. The film-forming agent is a biopolymer derived from starch, while the acid is a natural polymer that inhibits bacterial proliferation and promotes desquamation. The anti-allergic agent is a plant-derived extract, and the moisturizer component is a hyaluronic acid-based solution. The composition is formulated into a nasal patch that gently removes blackheads while minimizing skin irritation.
7. Blackhead Removal Composition with Synergistic Natural Extract Blend and Controlled Temperature Processing
GUANGZHOU BEST CLEAN COSMETIC MANUFACTURING CO LTD, Guangzhou Yachun Cosmetics Manufacturing Co., Ltd., 2023
A gentle, effective blackhead removal composition that combines synergistic action of natural ingredients to deeply penetrate and remove blackheads while maintaining non-irritating skin. The composition utilizes a balanced blend of Coptidis Rhizoma Root Extract, Clary Sage Extract, Saponaria Root Extract, Hypericum Perforatum Extract, and White Willow Bark Extract, which work together to inhibit oil production, shrink collagen fibers, and promote the natural exfoliation of blackheads and keratinized debris. This composition is formulated at a controlled temperature of 23°C for 50 minutes to ensure optimal efficacy and safety.
8. Cosmetic Composition with Isostearic Acid and Oleyl Alcohol for Lipid Dissolution in Cutaneous Comedones
LOREAL, 2022
A cosmetic composition and method for preventing and treating cutaneous blackheads and comedones through the controlled dissolution of their constituent lipids. The composition utilizes isostearic acid and/or oleyl alcohol, which exhibit potent dissolving properties against the lipids of cutaneous comedones and blackheads, particularly in non-acneic skin. The composition can be applied directly to the skin or combined with other active ingredients to enhance its therapeutic effects.
9. Composition of Natural Extracts with Hydrogenated Lecithin for Blackhead Removal
SHANGHAI A&H COSMETICS CO LTD, 2022
A composition for removing blackheads that combines the natural properties of witch hazel, white willow bark, artichoke leaf, lotus root seed, peppermint, and hydrogenated lecithin to create a gentle yet effective blackhead removal system. The composition balances exfoliating and soothing properties to prevent regrowth while maintaining skin health. The natural extracts in the composition work synergistically to improve skin maintenance, reduce inflammation, and promote skin regeneration, making it a safer alternative to traditional acid-based blackhead removal methods.
10. Cosmetic Composition with pH-Adjusted Alkaline System and Natural Actives for Blackhead Solubilization
LTD COSMETIC CO, 2022
A cosmetic composition for removing blackheads that combines a mild, pH-adjusted formulation with a synergistic solubilizing mechanism. The composition comprises a pH-adjusted alkaline system that softens keratin while facilitating blackhead extraction, and a combination of natural actives including plant extracts and surfactants that enhance penetration and solubilization. The formulation is particularly effective for blackhead removal due to its gentle, non-irritating properties and enhanced penetration capabilities.
11. Composition with Curcuma Radix, Black Willow Bark, Konjac Stem/Root, Hawthorn, and Shanna Root
GUANGZHOU KENENG COSMETIC RESEARCH CO LTD, GUANGDONG DANZI GROUP CO LTD, Guangzhou Konen Cosmetics Research Co., Ltd., 2022
A novel, synergistic oil-controlling and acne-removing composition comprising Curcuma radix, black willow bark, konjac stem/root, hawthorn, and shanna root. The composition effectively controls sebum production and reduces acne through its unique combination of antibacterial properties, anti-inflammatory effects, and natural moisturizing properties. The composition is particularly effective in facial masks, providing sustained acne control and improved skin texture.
12. Composition of Fruit Acid, Tanshinone, and Cucumber Extract for Blackhead Removal and Pore Size Reduction
ZHUHAI YASHA MEDICAL DEVICES CO LTD, 2021
A composition for removing blackheads and shrinking pores through a synergistic combination of ingredients that addresses the underlying causes of blackhead formation and pore enlargement. The composition utilizes a unique blend of ingredients including fruit acid, tanshinone, and cucumber extract, which work together to effectively remove blackheads while simultaneously reducing pore size. This composition is particularly beneficial for individuals with sensitive skin, as it provides gentle yet effective cleansing and pore-shrinking properties without causing irritation.
13. Blackhead Treatment Mask with Synergistic Blend for Oil Control, Hydration, and Keratin Disruption
SHUIYANG COSMETICS MFG CO LTD, 2021
A novel blackhead treatment mask that combines effective oil control, hydration, and blackhead removal capabilities. The mask contains a unique blend of ingredients that work synergistically to address the root causes of blackheads, including excessive oil secretion, while also providing long-lasting hydration and anti-inflammatory benefits. The composition achieves optimal blackhead removal through a combination of physical exfoliation, mechanical disruption of keratinized structures, and targeted delivery of active ingredients to the affected areas. The mask's formulation enables sustained hydration, oil absorption, and anti-inflammatory effects, making it a comprehensive solution for blackhead management.
14. Blackhead Removal Composition with Camellia Seed Oil Surfactant and Vitamin A Derivatives
HUNAN YUJIA COSMETICS MANUFACTURING CO LTD, 2021
A blackhead removal composition and cleansing cream that addresses the three dimensions of blackhead removal, skin cleansing, and long-term prevention through a unique surfactant and vitamin A combination. The composition contains a surfactant derived from camellia seed oil, vitamin A derivatives, and plant tannins, along with a moisturizing emollient and skin conditioning agents. The surfactant effectively cleans pores while preventing their recurrence, while the vitamin A derivatives provide sustained exfoliation and skin health benefits. The composition is formulated into a gentle, non-irritating cleansing product that addresses blackhead removal, skin cleansing, and long-term prevention through a comprehensive approach that targets multiple aspects of blackhead formation and skin health.
15. Cosmetic Composition with Natural Extracts and Acids for Exfoliation and Skin Conditioning
Min Mindy-seon, MIN, Mindy Sun, 2021
Complex cosmetic composition for removing dead skin cells, improving blackheads, soothing the skin, tidying texture, and supplying nutrients. It contains extracts from natural sources like flowers, oils, and acids along with ingredients like ceramides, hydrators, and excipients. The composition aims to provide exfoliation, blackhead care, soothing, texture improvement, and nutrition without skin irritation. The natural extracts include capryloyl salicylic acid, poly-alpha hydroxy acids, and alpha hydroxy acids for exfoliation. The flower extracts provide skin conditioning and nutrition. The composition also contains oils, ceramides, hydrators, and excipients.
16. Composition with Hydroxyphenylpropionamide Benzoic Acid, Witch Hazel, Glycerin, and Natural Extracts for Skin Exfoliation
GUANGZHOU SOYAWA BIO TECH CO LTD, 2020
A composition for removing blackheads that effectively and gently exfoliates the skin without irritation. The composition combines a combination of ingredients including a hydroxyphenylpropionamide benzoic acid, witch hazel, glycerin, and a proprietary blend of natural extracts, to create a gentle yet potent exfoliating agent that effectively removes blackheads while maintaining skin health.
17. Cosmetic Composition with Coagel Phase of Monoglyceride and Tartaric Ester Matrix Containing Salicylic Acid Compound
OREAL, 2020
Cosmetic composition comprising a monoglyceride, a tartaric ester of monoglyceride, and a salicylic acid compound. The composition utilizes a coagel phase that provides a stable matrix for the salicylic acid compound, allowing for enhanced skin penetration and stability. The composition can be formulated as an aqueous phase, with the coagel phase providing the aqueous phase. The coagel phase is a three-dimensional matrix containing a continuous aqueous phase, comprising a combination of monoglyceride and a tartaric ester of monoglyceride.
18. Composition with Nonionic Surfactant, Thickening Polymer, and Salicylic Acid Derivative
LOREAL, 2020
Composition for preventing and treating skin disorders associated with oily skin, comprising a surfactant with HLB 9.7 or higher, a thickening polymer, and a salicylic acid compound. The composition combines a nonionic surfactant with a thickening polymer to enhance solubilization of salicylic acid derivatives, particularly in cosmetic formulations with aqueous phases.
19. Blackhead Removal Composition with Honeysuckle, Sophora Flavescens, Wormwood Extracts and Lactic Acid Bacteria Fermentation Lysate
GUANGZHOU UNIASIA COSMETICS TECH CO LTD, 2020
Blackhead removal composition and method that effectively removes blackheads without irritating the skin. The composition contains extracts from honeysuckle, sophora flavescens, and wormwood, along with lactic acid bacteria fermentation lysate, organic acids, and water. The extracts help remove accumulated sebum and unclog pores, while the bacteria fermentation aids in oil control. The composition can be used to cleanse the skin and remove blackheads, leaving it clean and refreshed. The astringent and soothing composition contains fermented yeast/zinc, lecithin, cholesterol, peppermint, hydroxyphenylpropionamide benzoic acid, tea tree oil, rosemary oil, and water. It can be used to soothe the skin after blackhead removal. The blackhead removal composition can be made by combining
20. Facial Cleanser with Activated Carbon and Natural Ingredient Blend for Blackhead Removal
LI WENJIE, 2018
A natural blackhead facial cleanser that effectively removes blackheads while repairing the skin. The cleanser combines a proprietary blend of natural ingredients, including activated carbon, sodium lauryl sulfate, cucumber juice, deep sea fish oil, surfactants, yogurt, honey, pearl powder, and distilled water, to create a gentle yet potent cleanser for blackhead-prone skin.
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